Neurometabolic Disorders Market Report

Neurometabolic Disorders Market Analysis, Market Size, Application Analysis, Regional Outlook, Competitive Strategies, And Segment Forecasts, 2015 To 2022

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  • Report ID: GVR1934
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Global neurometabolic disorders market is expected to grow at lucrative rate during the forecast period owing to the increasing incidence of various neurometabolic disorders. The growing demand of rapid diagnostic techniques over current techniques due to factors such as long turnaround time, supportive government funding, increased awareness amongst patients & the physicians is expected to be high impact rendering drivers for the market growth. On the contrary presences of limited patient population to find the optimal dosage for the cure of the disease coupled with the high expenditure in the bioinformatics based research tends to restrain the market growth as the development of novel drugs is hindered.

The neurometabolic disorders market is categorized on the basis of type and route of administration. The types segment includes gaucher’s disease, fabry disease, pompe disease; mucopolysaccharidosis VI and niemann-pick type c disease. Out of the above enlisted disorders the gaucher’s disease held the substantial position in the market in 2014. High prevalence of this disorder as compared to the other aforementioned disease has led to the increased demand for treatment of the disease and has contributed to the growth of the segment. Fabry disease is expected to be the fastest growing segment over the forecast period owing to an increase in regulatory assistance and patient awareness. There are various pipeline products at different stages of development ranging from pre-registration till discovery and are to be developed over the forecast period. These are the drugs involved in the treatment of fabry disease, with the comparative analysis involving the therapeutics assessment by drug target, route of administration, mechanism of action and the type of molecule. One of the underlying reason for the growth in the market of the fabry disease is the special provisions for the orphan drugs. On the basis of route of administration the neurometabolic disorders are categorized into oral and parenteral. The oral route of administration held the largest share in 2014 pertaining to the ease it provides to the patients. Parenteral route of administration is however less preferred by the patients owing to the pain at the site of delivery.

Geographically, the neurometabolic market is segmented into North America, Europe, Asia Pacific, Latin America and MEA. North America held substantial market share in 2014 owing to numerous research in the field of bioinformatics and transcriptomics to incorporate the gene level study of the disease. The major factors attributing towards the high share of the region include genomics based biopharmaceutical research, drug design, increasing awareness for the diagnosis and treatment in the adolescent section of the population. Presences of various economic leverages by the U.S. FDA are also expected to boost the market growth. The leverages include exemption from prescription drug fees for the orphan drugs, tax credits for qualified clinical testing, and market exclusivity for seven years for diagnostics and the drug manufacturing companies that are into orphan drug manufacturing. Moreover, presences of many institutional bodies that are involved in orphan disease research are expected to boost the market growth positively. These organizations are employing the novel techniques such as gene targeting to sort out the frequent gene mutations and prepare the new drug moieties for better treatment of the disorder. Asia Pacific region is expected to exhibit substantial growth over the forecast period on account of rapidly improving healthcare infrastructure in this region.

Key companies in neurometabolic disorders market include Amicus Therapeutics, ISU Abxis, JCR Pharmaceuticals, Biosidus., Greenovation Biotech, UAB Proforma, Dong-A Socio Group, ExSAR Corporation, Lixte Biotechnology Holdings, Inc, Neuraltus Pharmaceuticals, Protalix, Pharming Group N.V., Protalix BioTherapeutics, Amicus, Biomarin, Genzyme, Shire, Greencross. Launch of novel drugs is the major strategy adopted by the market players to capture significant share. The key market players are adopting competitive marketing strategies to maintain their market share such as the introduction of combination therapies like fabrazyme and replagal with less immunogenicity reactions by Amicus Therapeutics. Special incentives from the government in the form of guiding, funding and market exclusivity make it convincing opportunity for vendors to conduct research and develop versatile therapies.


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