Protein expression forms an integral part of proteomic research which is in high growth phase. Decline in productivity of research & development in pharmaceuticals, increasing intensity of research, rise of biologics market, sales drop resulting by upcoming patient cliffs are the vital drivers for this market. The protein expression system is segmented into Eukaryotic expression system & Prokaryotic expression system. The prokaryotic expression system is having the highest market share of protein expression market followed by eukaryotic expression system which is expected to grow at CAGR owing to increasing demands of therapeutic proteins used for human treatment.
The market for prokaryotic expression system has been divided into four segments globally which are products, applications, end-users, host types. Host types market is sub-segmented into archaea, B.subtilis, C.glutamicum, E.coli systems & P.alcaligenes. Product market includes amino acids, biopolymers, ascorbic acids, pigments, & enzymes. Application of prokaryotic expression system includes research applications, therapeutic proteins & industrial proteins. Academic research, biotechnological companies, pharmaceuticals & contract research organizations are the end users for prokaryotic expression system. E.coli is one of the most used artificial expression host. Production of protein through E.coli is quick & cost effective method. Physiology & genomic sequence of E.coli facilitates the gene cloning procedure making it the most popular host. The techniques for over expression are well developed in E.coli. They work by increasing the binding strength of the promoter region 7 hence assist in the process of transcription. Manufacturing commercial proteins & using them in pharmaceuticals & biotechnology is an important application of prokaryotic expression.
The prokaryotic expression system market is globally classified in North America, Europe, Asia-Pacific & RoW. North America is expected to hold the maximum market share in this market. The developing economies in Middle East & Asia Pacific are expected to have a relevant growth in this market owing to huge untapped potential & increased expenditure in research & development. Key players of the prokaryotic expression systems market are Thermo Fisher Scientific, Life Technologies Corporation, Takara Bio Inc., Bio Rad Technologies, Promega Corporation, Agilent Technologies, Merck Millipore, Sigma Aldrich Corporation & Qiagen.
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