GVR Report cover Protein A Resins Market Size, Share & Trends Report

Protein A Resins Market Size, Share & Trends Analysis Report By Type (Natural Protein A, Recombinant Protein A), By Product, By Application, By End-user, By Region, And Segment Forecast, 2022 To 2030

  • Report ID: GVR453493
  • Number of Pages: 0
  • Format: Electronic (PDF)

Protein A resins are the most frequently used resins in affinity chromatography mediums in bio-manufacturing. They are designed to achieve easy, one-step purification of fragments, sub-classes, and classes of immunoglobulins from cell culture media and biological fluids. It can also be used for the immunoprecipitation of antigens, proteins, and protein complexes. Rising focus on drug development by pharmaceutical and biotechnology companies and increasing investments in synthetic biology are expected to accelerate industrial growth. Protein-engineered products are widely used in biopharmaceutical industries in their research activities to develop drugs. Due to the high affinity and selectivity of protein A resins 99% purity can be gained in the utmost generic form.

Monoclonal antibodies have proven to be efficient, effective, and better tolerated in treating various diseases including cancer. Many strategic initiatives are being taken by several companies to develop monoclonal antibodies to treat COVID-19. For instance, in May 2022, RQ biotechnology received funding of $157 million from a licensing deal with AstraZeneca to focus on the development of early stage monoclonal antibodies against COVID-19 infection. In addition, in May 2022, Roche pharma launched a drug for breast cancer using two monoclonal antibodies Perjeta (pertuzumab) and Herceptin(trastuzumab) which can be administered by single injection and reduces the treatment time by 90%. Since protein A resins are required in the purification of antibodies, increase in monoclonal antibodies to treat various diseases is expected to boost the protein A market growth during the forecast period.

Increasing demand for disposable pre-packed columns owing to their benefits such as operational flexibility with rapid changeovers and quicker set up are increasing their adoption in the manufacturing process. Furthermore, these columns eliminate the work involved in sterilization, packing and cleaning, reduce labor-time including column testing, validation, and documentation, and allow for more runs. The protein A resins are packed in the disposable pre-packed columns, therefore a growing demand for disposable pre-packed columns significantly fuels the protein A market.

Furthermore, the development of novel resins from several players in the market to address the key requirements in the industry is anticipated to drive the market. For instance, in October 2021, Purolite reported the commercialization of two protein A resins Praesto Jetted (dT)18-DVB and Praesto Jetted A50 HipH designed for the purification of antibodies. Similarly, in March 2020, Avantor launched a novel protein a resin PROchievA to improve the downstream purification for monoclonal antibodies production in bioprocessing industry.

The market is segmented by type, product, application, end-user and region. The type segment is based on natural protein A and recombinant protein A. The product segment is based on agarose- based protein A, glass/silica based protein A, and organic polymer based protein A. The application segment is based on antibody purification and immunoprecipitation. The end-user segment is based on pharmaceutical and biopharmaceutical companies, academic research institutes and others.




  • Natural Protein A
  • Recombinant Protein A


  • Agarose-based Protein A
  • Glass/Silica-based Protein A
  • Organic Polymer-based Protein A


  • Antibody Purification
  • Immunoprecipitation


  • Pharmaceutical & Biopharmaceutical Companies
  • Academic Research Institutes
  • Others


  • North America
  • Europe
  • Asia Pacific
  • Latin America
  • Middle East & Africa


Key players in the global Protein A Resins Market include GE Healthcare, Merck Millipore, PerkinElmer, GenScript Biotech Corporation, Agilent Technologies, Repligen Corporation, Thermo Fisher Scientific, Bio-Rad Laboratories, Abcam, and Novasep Holding SAS, among others.

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