The global pupillometer market size was valued at USD 332.4 million in 2021 and is projected to expand at a compound annual growth rate (CAGR) of 7.7% from 2022 to 2030. Pupillometry is extensively used to measure pupil dilation for understanding underlying conditions. Various imaging modalities such as MRI and CT have identified that changes in brain activity have a direct impact on pupil dilation. Thus, measuring pupil dilation helps in understanding cognitive processes at a deeper level.
On the other hand, individuals with depression, anxiety, Parkinson’s disease, and autism spectrum disorder have also shown abnormal pupillometry responses toward stimuli. Therefore, pupillometry helps in understanding the normal eye functionality of an individual along with the brain activity impacted by a disease.
Pupil dilation can help in offering clues to understanding the lives of people with neurological disorders. Pupillometry results help in determining the physiological treatment. Usage of pupillometers can be an effective option to understand the best possible treatment for an individual. This, in turn, is expected to improve diagnostic outcomes, thus increasing recovery rates.
Furthermore, pupillometry can also be used with other systems or processes to enhance the diagnosis of neurological diseases. Brain-computer-interaction (BCI) can be enhanced using pupil dilation study, as it will act as an additional signal to understand the neurological signals.
The COVID-19 pandemic had a negative impact on the pupillometer industry. Factors such as global lockdowns and restrictions laid down by governments, increased focus on COVID-19 infected patients, and postponement of patient visits to medical facilities to curb the spread of the virus resulted in a drop in sales of pupillometer in 2020.
However, the market began to recover in 2021 and gained significant sales, although a complete recovery will only be observed by the end of 2022, making it reach the pre-COVID growth rate. Additionally, the launch of new products will further boost the growth of the market during the forecast period. For instance, in June 2022, NeuroOptics launched its NPi-300 automated pupillometer in 15 countries. The NPi-300 pupillometer augments pupillary assessment to assist in identifying cerebral insult, managing treatment, and reporting prognosis for clinicians and their patients.
Advantages associated with pupillometry are resulting in its increasing adoption. Various critical care units such as neurocritical care, surgical intensive care, cardiac intensive care, medical intensive care, pediatric intensive care, trauma, and emergency departments are adopting pupillometers. Frequent pupil evaluation is now becoming the protocol in critical care units. Pupil size and pupillary light reflex (PLR) are being used as prognostic indicators and clinical parameters by various associations and centers.
The Brain Trauma Foundation and the American Association of Neurological Surgeons recommend the usage of pupillary light reflex for each eye as a prognostic parameter. Usage of this on patients with neurological injuries helps in facilitating the measurement of pupil dynamics of the patients provided with prescribed medications such as sedatives, analgesics, and anesthetic agents.
Various nursing associations provide training and knowledge regarding pupillometry as it is becoming the key assessment for neurological examination. The American Association of Critical-Care Nurses (AACN) has featured a new section on pupillometry, to guide nurses regarding automated pupillometers in its Procedure Manual for High Acuity, Progressive and Critical Care.
The table-top pupillometer segment held a higher market share of 54.4% of the global revenue in 2021. A large number of pupillometers come in combination with other devices such as keratometers, pachymeters, wavefront aberrometers, corneal topographers, and others. These combined pupillometers, mainly table-top pupillometers, are installed in various facilities such as hospitals.
Market players like HAAG-STREIT GROUP, Johnson & Johnson Vision, and SCHWIND eye-tech solutions are developing combined table-top pupillometer devices. In November 2017, Johnson & Johnson Vision announced the launch of a series of products in various portfolios at the American Academy of Ophthalmology 2017 Meeting. The company introduced the iDESIGN system, which received approval from the FDA for expanded indications. The system gathers readings such as information regarding wavefront refraction, corneal topography, wavefront aberrometry, pupillometry, and keratometry.
Similarly, SCHWIND eye-tech solutions have also developed the SCHWIND Combi Wavefront Analyzer. This analyzer combines the capabilities of SCHWIND PERAMIS and SCHWIND SIRIUS into a 3-in-1 solution. An integrated pupillometry function of the system helps in capturing the pupil diameter either statically or dynamically. On the basis of mobility, the pupillometer market is segmented into table-top and hand-held.
The hand-held pupillometers segment is expected to expand at the fastest growth rate during the forecast period. A hand-held pupillometer allows the user to efficiently and accurately obtain the pupil image, which can be helpful in diagnosing various neurological diseases such as Alzheimer's. Moreover, the easy mobility of the hand-held pupillometer has led to its increasing development and adoption. NeurOptics is one of the leading players in the market that develops hand-held pupillometer for critical care as well as applied research.
Additionally, companies such as Adaptica have come up with a combined hand-held device called 2WIN, which includes pupillometry as a feature. The dynamic pupillometry (DP-App), which is an additional feature of the product, helps in detecting pupillary changes, pupil distance, and pupil size. The development of advanced hand-held pupillometers is expected to propel the overall segment growth during the forecast period.
The video pupillometer segment held the largest revenue share of 56.5% in 2021 and is expected to advance at a significant rate during the forecast period. Video pupillometer helps in capturing the entire activity of pupil dilation, which helps in understanding the changes and reason for the same.
NeurOptics is a company that deals in the science of pupillometry by developing innovative technologies to help clinicians in providing better patient care. The company has come up with various video pupillometers for critical care as well as applied research. NPi-200 pupillometer is a video pupillometer developed by NeurOptics for critical care. This product is equipped with an infrared camera, processor, high-precision optics, and LED light source. The video feature of this product helps in capturing the changes in pupil size and its reactivity over time.
VIP-300 pupillometer, PLR-3000 pupillometer, and DP-2000 are also video pupillometers by NeurOptics that are used for applied research. Some of these video pupillometers are hand-held, whereas some are tabletop. These devices store data of the pupil measurement which can later be played or recalled on a screen. This, in turn, helps in increasing the efficiency of clinicians while capturing pupil movement, pupil size, and other changes in the pupil due to medication or disease.
Additionally, the integrated systems by various market players such as Essilor and HAAG-STREIT also include video pupillometry in their products. LENSTAR LS 900 and APS by HAAG-STREIT and Wave Analyzer Medica (WAM) 700 by Essilor are a few of the combined devices with video pupillometer. Based on type, the global pupillometer industry is fragmented into video and digital segments.
The digital pupillometer segment is expected to experience the fastest growth rate during the forecast period. The product helps in an accurate and rapid assessment of pupil size. This device captures several frames in a second and averages the measurements to determine pupil dilation. A digital pupillometer helps in capturing all the fluctuations happening in the pupillary response, which in turn enhances the detection of neurological diseases. Market players such as Essilor, Luneau Technology Group, and Reichert Technologies have developed digital pupillometers for proper diagnosis.
The ophthalmology segment held the largest revenue share of 49.4% in 2021, owing to the rising usage of pupillometry for checking pupil dilation, which, in turn, helps in assessing retinal diseases. Pupillary light reflex helps in assessing visual system functionality. Pupillometry identifies differences in the response of melanopsin and cone/rod photoreceptors to understand the damage to the outer and inner retina.
Additionally, the measurement of pupil size helps refractive surgeons in understanding the after-effects of LASIK surgery. Patients measured for large pupils are likely to have increased post-LASIK visual disturbances in scotopic conditions. This increases the adoption of pupillometry in ophthalmic diagnostics, which is expected to enhance the overall segment growth. On the basis of application, the market is segmented into ophthalmology, neurology, oncology, and others.
Neurology held a significant share and is expected to expand at the fastest growth rate during the forecast period. Various studies are being conducted regarding the usage of pupillometry in diagnosing neurological disorders. The examination of pupillary light reflex (PLR) is helpful in neurological assessment. PLR assessment helps in examining the functional status of the optical nerve and oculomotor nerve. Impaired PLR is the risk indicator of the horizontal shift of the intracranial tissues or central brain herniation.
Usage of a non-invasive tool like a pupillometer helps in monitoring the neurological conditions of patients in the ICU. A pupillometer helps in measuring pupil constriction, pupil size, dilation velocities, and latency. Growing usage of pupillometer in the field of neurology is driving its development by market players. NeurOptics NPi-200 is a critical care pupillometer by NeurOptics, which is used in neurological care units to assess neurological procedures.
Usage of pupillometry in the field of oncology is gradually increasing. Clinical trial studies are being conducted to understand the effectiveness and efficiency of pupillometry in oncology. Pupillometry for brain tumors is in practice across various settings, whereas studies are being conducted to understand the depth of anesthesia using a pupillometer for health conditions such as breast cancer, thyroid tumor, and stroke.
Determination of pupil size, pupillary response, pupillary unrest, and other pupillary characteristics can be an indication of conditions such as head trauma, brain tumor, or stroke. Therefore, a growing number of studies regarding pupillometry in oncology is expected to contribute to the segment growth during the forecast period.
The hospitals segment held the largest revenue share of 49.7% in 2021 in terms of end-use, owing to the increasing adoption of pupillometers in this setting. Pupillometer developed by NeurOptics has been adopted by 400 hospitals around the U.S., thus contributing to the growth of the segment. Additionally, the growing usage of pupillometers in critical care units is also expected to contribute to the segment growth. NeurOptics pupillometer is used in various critical care units such as neurocritical care, medical intensive care, emergency department, and cardiac intensive care.
The eye clinic segment is expected to advance at the fastest rate during the forecast period. Various eye clinic diagnostic departments have included pupillometry as one of the major diagnostic procedures. Ophthalmic clinics have involved pupillometry in their diagnostic examinations and prevention control departments. Pupillometry is used as a pre-operative measure along with wavefront technology in the clinic before refractive surgery, to avoid post-surgery vision problems.
London Vision Clinic Partners Ltd. also used pupillometry as an assessment test before ophthalmic surgeries. Pupillometry results help in determining the type of laser treatment required for the eye. Therefore, the growing adoption of pupillometry by various eye clinics is expected to enhance the segment growth during the forecast period.
The other segment includes research institutions, research centers, and education centers/associations. Research institutions and centers are conducting research to understand the efficiency and effectiveness of pupillometry in other applications such as oncology. On the other hand, since the adoption of pupillometry is increasing in the field of neurology, this is driving education centers or associations to include it as one of the segments.
The new Core Curriculum for Neuroscience Nursing by the American Association of Neuroscience Nurses (AANN) has included a section on automated pupillary assessment. This section talks about the usage of pupillometers to understand pupillary reactivity in an objective, consistent, and quantifiable way.
North America dominated the market and accounted for around 26.3% share of global revenue in 2021, owing to the increasing prevalence of vision-related problems and neurological disorders in the regional population. Additionally, the adoption and installation of a pupillometer across various settings in the U.S. are expected to drive the overall market growth.
Major market players such as NeurOptics are headquartered in the U.S. and developing advanced pupillometers for enhanced diagnosis in the country. Moreover, the company is also researching the usage of pupillometers in various critical care fields to increase its product reach for different health conditions.
The Asia Pacific region is expected to expand at the fastest rate during the forecast period. The growing availability of pupillometer in the region through various online platforms and suppliers is expected to contribute to the segment growth. Additionally, global market players such as NeurOptics, Johnson & Johnson Vision, and Konan Medical are providing a pupillometer through their subsidiaries.
NeurOptics is providing its pupillometer through its distributors Hansraj Nayyar Medical India, IMI Co., and Neuroplus, in India, Japan, and South Korea respectively. Furthermore, the presence of global players such as NIDEK has also increased the availability and accessibility of pupillometer in the region.
Europe is also expected to progress at a considerable rate during the forecast period. Major market players such as SCHWIND eye-tech-solutions, Luneau Technology Group, and HAAG-STREIT GROUP are located in the region and are developing advanced digital as well as video pupillometers. Additionally, these market players are incorporating pupillometry in various other ophthalmic diagnostic devices, and hence are offering integrated products. These products are expected to replace traditional products, thus boosting the market growth.
The key players that dominated the global market in 2021 were NeurOptics, Inc., Essilor Instruments USA, HAAG-STREIT GROUP, and SCHWIND eye-tech-solutions. These companies are developing digital and integrated pupillometers with advanced features to be used for various clinical applications in critical care units. Additionally, companies such as bright lamp, Inc. are focusing on integrating advanced technology into pupillometry to provide easily accessible pupillometry through mobile devices. Some prominent players in the global pupillometer market include:
Essilor Instruments USA
Johnson & Johnson Vision
Luneau Technology Group
NIDEK CO., LTD.
Market size value in 2022
USD 372.6 million
Revenue forecast in 2030
USD 674.0 million
CAGR of 7.7% from 2022 to 2030
Base year for estimation
2017 - 2021
2022 - 2030
Revenue in USD million and CAGR from 2022 to 2030
Revenue forecast, company ranking, competitive landscape, growth factors, and trends
Mobility, type, end-use, application, region
North America; Europe; Asia Pacific; Latin America; MEA
U.S.; Canada; U.K.; Germany; France; Italy; Spain; Russia; Netherlands; Switzerland; Turkey; Poland; China; India; Japan; Thailand; South Korea; Indonesia; Taiwan; Hong Kong; Philippines; Malaysia; Mexico; Brazil; Colombia; Argentina; Chile; South Africa; Saudi Arabia; UAE; Kuwait; Qatar
Key companies profiled
NeurOptics, Inc.; Adaptica; Essilor Instruments USA; HAAG-STREIT GROUP; Johnson & Johnson Vision; Luneau Technology Group; NIDEK CO., LTD.; Reichert Technologies; SCHWIND eye-tech-solutions; US Ophthalmic; Konan Medical; Brightlamp, Inc.
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This report forecasts revenue growth at global, regional, and country levels and provides an analysis of the latest industry trends in each of the sub-segments from 2017 to 2030. For the purpose of this study, Grand View Research has segmented the global pupillometer market report based on mobility, type, end-use, application, and region:
Mobility Outlook (Revenue, USD Million, 2017 - 2030)
Type Outlook (Revenue, USD Million, 2017 - 2030)
End-use Outlook (Revenue, USD Million, 2017 - 2030)
Application Outlook (Revenue, USD Million, 2017 - 2030)
Regional Outlook (Revenue, USD Million, 2017 - 2030)
Middle East & Africa
b. The global pupillometer market size was estimated at USD 332.41 million in 2021 and is expected to reach USD 372.6 million in 2022.
b. The global pupillometer market is expected to grow at a compound annual growth rate of 7.7% from 2022 to 2030 to reach USD 674.0 million by 2030.
b. North America dominated the pupillometer market with a share of 26.2% in 2021. This is attributable to the increasing prevalence of vision-related problems, neurological disorders, and the growing installation of pupillometer in hospitals in the U.S.
b. Some key players operating in the pupillometer market include NeurOptics, Inc., Adaptica, Essilor Instruments USA, HAAG-STREIT GROUP, Johnson & Johnson Vision, Luneau Technology Group, NIDEK CO., LTD., Reichert Technologies, SCHWIND eye-tech-solutions, US Ophthalmic, Konan Medical, and brightlamp, Inc.
b. Key factors that are driving the pupillometer market growth include an increasing number of neurological disorders, an increasing number of vision-related issues, and a growing number of product launches.
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