Single-use Mixers Market Size, Share & Trends Analysis Report By Product (Mixing Systems, Consumables & Accessories), By Application, By End-user, By Region, And Segment Forecasts, 2023 - 2030

Single-use Mixers Market Size & Trends

The global single-use mixers market size was valued at USD 1.21 billion in 2022 and is expected to grow at a CAGR of over 8.42% during the forecast period. The growing demand for biopharmaceuticals, the increasing concern for the environment, and the rising menace of cross-contamination are the major factors responsible for the growth of the single-use mixers industry. In addition, the increasing adoption of single-use technology, and huge cost benefits in terms of construction and operation are other drivers which are expected to fuel the market growth of single-use mixers (SUM).

According to an article published by WHO, in November 2022, nearly 16 billion vaccine doses, worth USD 141 billion, were supplied in the year 2021, which is approximately thrice the market volume of 2019 (that is 5.8 billion) and about three-and-a-half times the market value of 2019 (USD 38 billion). The primary driver to increase the industry growth of SUM is the production of vaccines. The COVID-19 vaccines were principally responsible for the rise, demonstrating the great potential for scaling up vaccine production in response to medical requirements. In addition, despite an expansion in manufacturing capacity worldwide, it is still very concentrated, 70% of vaccination doses are supplied by ten manufacturers alone (excluding COVID-19). Due to the urgent need for vaccines and therapeutics to combat the pandemic, the development and manufacturing of vaccines and therapeutics require the use of single-use technologies such as SUM, which helped to ensure the products are safe and free from contamination. Thus, increasing the demand for the production of vaccines is anticipated to propel the upsurge of the market.

Various government initiatives in the production of vaccines are also expected to grow the demand for SUM over the forecast period. For instance, until March 2022, the U.S. government invested around USD 31.9 billion to develop, make, and buy mRNA covid-19 vaccines, including significant investment in the three decades prior to the pandemic. Furthermore, in June 2020, to accelerate the production, and distribution of vaccines against COVID-19, the European Commission unveiled the EU Vaccines Strategy. In addition, in May 2021, the federal government confirmed a USD 200 million investment to support the construction of a factory in Mississauga, Ontario, that will produce millions of mRNA vaccines. Hence, various initiatives and investments made by governments are expected to bolster the expansion of the industry.

The growing trends in the biopharmaceutical industry are anticipated to be the progression of the industry.The shift towards personalized medicine is driving the growth of the biopharmaceutical industry, thus, fueling the growth of SUM. Moreover, the increasing demand for biosimilars is also driving the growth of single-use technology. In May 2021, the biopharmaceutical industry reaffirms its commitment to working with governments to assist the initiatives that it made to the G20's COVID-19 response. Specifically, the industry pledged to continue providing treatments, vaccines, and diagnostics to combat the COVID-19 pandemic, and to support the World Health Organization's Access to COVID-19 Tools Accelerator (ACT-A) initiative. Thus, anticipated to propel the development of the market during the estimated period.

Product Insights

In 2022, the consumables & accessories segment dominated with a market share of 58.03% and is estimated to have the highest CAGR of 9.33% during the forecast period. This is attributed to the increasing demand for mixing various fluids such as buffers, culture media, and processes for various research purposes and vaccine production. Furthermore, many consumables and accessories such as mixing bags, can be customized as per the demand of the client, thus reducing the costs and minimizing the contamination risk, henceforth helping keep the environment clean.

Mixing systems are an important tool for R&D applications in the biopharmaceutical industry. Factors such as flexibility, scalability, cost-effectiveness, and reduced contamination risk make them an attractive option for R&D centers. Moreover, the mixing system eliminates the need for cleaning and sterilization, which reduces the time and resources required to prepare and conduct experiments.

Application Insights

In 2022, the research and development (R&D) & process development segment dominated the industry with a market share of 65.41% due to the tractability, scalability, cost-effectiveness, and reproducibility provided by these systems. SUM is particularly well-suited for vaccine development, where small variations in experimental conditions can have a significant impact on the final product. Thus, R&D & process development centers are increasingly turning to single-use technology to support them in conducting experiments speedily and with greater precision, which is driving the progress of the research and development (R&D) & process development segment for the industry.

Commercial manufacturing is anticipated to have the highest CAGR of 10.17% during the forecast period. The acceptance of technology in commercial manufacturing has been steadily increasing over the past decade. However, there are still some barriers to widespread adoption at the commercial level. One of the main reasons for the limited uptake of disposable is the perception of higher costs compared to traditional stainless-steel equipment. Although disposable equipment is more expensive upfront, it often delivers cost savings over the period due to reduced cleaning and validation requirements, and shorter turnaround times. Furthermore, these mixers generate less waste compared to traditional mixing methods, which helps reduce the environmental impact of commercial manufacturing processes. Biopharma companies have slowly started to use SUM for commercial manufacturing, that is, for large-scale production of biologics focusing on efficient and consistent production.

End-User Insights

In 2022, the pharmaceutical & biotechnology companies segment dominated with a market share of 43.06 % due to the major commercial success of biologics. Bio-manufacturers are the key end-users of single-use technologies, including SUM. The benefits such as cost-effectiveness, compliance, flexibility, and adoption of innovative techniques give pharmaceutical & biotechnology opportunities to improve the manufacturing process. Thus, the rising demand for better production of vaccines and other biologics in a cost-effective way is anticipated to strengthen the industry in future years.

CMOs & CROs segment is anticipated to have the highest CAGR of 9.97% during the forecast period. Contract Manufacturing Organizations (CMOs) and Contract Research Organizations (CROs) maintain competitiveness by producing biologics more effectively and affordably, especially for R&D and clinical trials. For instance, according to an article published by SIAPARTNERS in April 2022, approximately 60% of the companies indicated savings of around 10% to 25% through outsourcing, while the remaining 40% reported their savings up to 40%. The use of single-use technologies offers many benefits for CMOs and CROs, including improved flexibility, faster turnaround times, and reduced capital expenditures, hence it is anticipated to increase the demand for the market.

Regional Insights

In 2022, North America dominated the industry with a revenue share of 36.09%. The large share of this region is attributed to an increase in the adoption of novel technologies and biopharmaceuticals in the region for the analysis and treatment of clinical ailments. Additionally, a great number of market players in the region are engaged in the constant improvement of advanced tools for biopharmaceutical research. Moreover, government funding for research is estimated to bolster the industry of SUM. For instance, in June 2021, the U.S. Department of Agriculture’s (USDA) National Institute of Food and Agriculture (NIFA) made an investment of USD 5.4 million in bioengineering, bioprocessing, and biofuels, along with various other biobased product research.

Asia Pacific is anticipated to register the highest CAGR of 13.22% during the forecast period. The significant progress in the pharmaceutical and biotechnology industries in the region is one of the major factors contributing to the development of single-use technology. The countries like China, India, and Japan are estimated to witness lucrative growth due to growing government investment in R&D centers, thus influencing the significant use of SUM in vaccine production and other research. In India, in the 2022 budget, the Ministry of Science and Technology was given a budget of Rs. 14,217 crores (i.e. USD 1,706.04 million).

Key Companies & Market Share Insights

Companies are leveling on manufacturing novel medical products, developments, and advancements in technology. In addition, acquisitions and mergers for novel product development constitute some of the initiatives implemented by major players. For instance, in January 2023, Pall Corporation announced the expansion of a new platform that will be dealing with the rising demand for viral vectors, especially adeno-associated virus (AAV) vectors. Thus, utilizing the company's expertise as a Contract Development and Manufacturing Organization (CDMO) to decrease process development time by up to 40%. Furthermore, in May 2021, Avantor announced the expansion of the organization’s facilities in North Caroline. Moreover, the organization will be increasing the manufacturing of single-use manufacturing by 30% in both U.S. as well as Europe, thus anticipated to propel the growth of the single-use mixers market. Some of the key players operating in the global single-use mixers market include:

• Sartorius Stedim Biotech

• Danaher

• Merck KGaA

• Thermo Fisher Scientific, Inc.

• Meissner Filtration Products, Inc.

• DrM, Dr. Mueller AG

• VWR International, LLC. 

• CerCell A/S

• AGILITECH

• Holloway America, LLC. 

Single-use Mixers Market Report Scope

Global Single-use Mixers Market Report Segmentation

This report forecasts revenue growth and provides an analysis of the latest trends in each of the sub-segments from 2018 to 2030. For this study, Grand View Research has segmented the global single-use mixers market based on product, application, end-user, and region:

• Product Outlook (Revenue, USD Million, 2018 - 2030)

  • Mixing Systems

  • Consumables & Accessories

• Application Outlook (Revenue, USD Million, 2018 - 2030)

  • Research and Development (R&D) & Process Development

  • Commercial Manufacturing

• End-User Outlook (Revenue, USD Million, 2018 - 2030)

  • Pharmaceutical & Biotechnology Companies

  • CMOs & CROs

  • Academic & Research Institutes

• Regional Outlook (Revenue, USD Million, 2018 - 2030)

  • North America

    • U.S.

    • Canada

  • Europe

    • UK

    • Germany

    • France

    • Italy

    • Spain

    • Denmark

    • Sweden

    • Norway

  • Asia Pacific

    • Japan

    • China

    • India

    • Australia

    • South Korea

    • Thailand

  • Latin America

    • Brazil

    • Mexico

    • Argentina

  • Middle East & Africa

    • South Africa

    • Saudi Arabia

    • UAE

    • Kuwait