Single-Use Mixers Market Size, Share & Trends Analysis Report By Product (Mixing Systems, Consumables & Accessories), By Application, By End-user, By Region, And Segment Forecasts, 2023 To 2030

Mixing is complex process critical for successful production of homogenous batches of biologicals. Mixing equipment is necessary for multiple operations such as suspension, homogenization, heat exchange and dispersion during buffer and medium preparation, fill & finish, virus inactivation, cell culture, and fermentation. The key advantages of using single-use mixers as compared to traditional stainless steel mixers are reduced risk of contamination, potential cost savings of up to and exceeding 60%, ease of use of single-use products in the pharmaceutical validation and quantification procedures, as well as reduced sterilization and cleaning demands. 

Recently, contract manufacturing organizations (CMOs) have been incorporating single-use technology into most or all their bioprocess. CMOs widely use single-use mixers for quicker process and processing changeover time. The quick flexibility and turnaround time between process runs and various client projects allowed by single-use mixers can enhance the CMO efficiency. Furthermore, single-use mixers in CMOs decreases the complexity and reduces lead times in upstream processes. They also enhance the quality of products by preventing cross-contamination in downstream processes, especially for processes handling of potent or toxic materials, such as antibody-drug conjugates and viral vectors. Moreover, stringent regulatory requirements in the manufacturing systems also boost the adoption of single-use mixers in CMOs. 

Operating players in the market are launching novel mixing systems for numerous applications to meet the untapped opportunities in the market. For instance, in July 2021, Distek, Inc. introduced a novel BIOne Mixing System for downstream and upstream applications. Furthermore, technological advancements associated with single-use mixers can drive the market during the forecast years. For instance, Sartorius AG designed Flexsafe Pro Mixer by integrating computational fluidics (CFD) to allow in-line control and monitoring, decrease the risk of operator error, allow easy setup and quick installation, and protect shear-sensitive products. 

Moreover, single-use mixers aid in the large scale production of biologics such as monoclonal antibodies by reducing the cost for process development. Monoclonal antibodies are rapidly progressing in the field of cancer therapy. Hence, growing approvals of monoclonal antibodies is anticipated to drive the market during the review period. For instance, according to an article published in by mAbxience in January 2021, 27 monoclonal antibodies are approved for treating different types of cancer. In addition, Tebentafusp-tebn monoclonal antibody for the treatment of metastatic uveal melanoma was approved by FDA in January 2022. 

The market is segmented based on product, application, end-user, and region. The product segment includes mixing systems and consumables & accessories. The application segment comprises upstream bioprocessing, fermentation, downstream bioprocessing. The end-user segment is further segmented into biopharmaceutical & pharmaceutical companies, CROs & CMOs, and academic & research institutes.

                                             Single-Use Mixers Market Segmentation 

There are a number of major companies that are operating in the single-use mixers market. Some of the leading players in this market include: Merck KGaA, Thermo Fisher Scientific Inc., Danaher (Cytiva), Avantor Inc., Sartorius AG, DrM Life Science, LePure Biotech LLC, Meissner Filtration Products, Inc., Kuhner AG, Agilitech