Spatial genomics & transcriptomics market is driven by recent technological advances pertaining to the development of in situ methods which enhance the capabilities to explore spatial information in the biological studies. These methods have led to the convergence of function-oriented field of biochemistry and molecular genetics with structure-focused fields such as histology and embryology, thereby enabling spatially resolved molecular investigation of biological processes.
For example, combination of in-situ hybridization techniques with genetic tools facilitates in exploring the formation of gene expression gradients along with the embryonic axes at different developmental stages. This gradient formation helps in understanding the embryonic development and organ formation
Analysis of chromatin structure in single cells and tissues sections has laid the foundation for in depth biological research and further implementation of data sets in clinical practice, thereby driving the attention of entities involved in genetics arena. Furthermore, constant improvement in genome perturbation tools like CRISPR/Cas9 system is aiding in the growth of this market.
Understanding the potential of spatial genetics/transcriptomics analysis in healthcare sector, several entities have begun investing in the development of products to serve the research demand. For example, in 2016, Spatial Genomics entered the market and is engaged in development of single cell spatial sequencing technology that will capture 3D coordinates of single cells in tissue for NGS readout.
Some key participants are 10x Genomics.; Dovetail Genomics; Illumina, NanoString Technologies, Seven Bridges Genomics, Horizon Discovery Group plc, CARTANA AB, READCOOR,. Advanced Cell Diagnostics, Inc. (ACD). These companies are engaged in collaboration and partnerships for development of novel platforms in order to cater the changing demands from research communities.
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