Nucleic Acid Isolation & Purification Market To Reach $12.84 Billion By 2033

Nucleic Acid Isolation And Purification Market Growth & Trends

The global nucleic acid isolation and purification market size is estimated to reach USD 12.84 billion by 2033, registering a CAGR of 10.07% from 2026 to 2033, according to a new report by Grand View Research, Inc. The growth is attributed to the increasing number of cancer cases, chronic diseases prevalence, and rising public-private funding for biotechnology and life sciences research. In addition, advancements in automation and technology, and growing demand for genetically modified crops and organisms also contribute to the market growth. For instance, in December 2023, HiMedia Labs elaborated the significance and efficacy of magnetic bead-based systems in nucleic acid extraction and applying nucleic acid isolation and purification in various end-use industries.

The number of precision medicines developed for treating multiple diseases, such as diabetes, cancer, rheumatoid arthritis, neurological diseases, and autoimmune diseases. This market is introduced with the various new approaches, aiding the manipulation of genes. For instance, the companies are investing in a platform that delivers nucleic acids, such as small interfering RNAs (siRNAs), to address gene overexpression and mutations in conditions such as cancer, genetic disorders, and autoimmune diseases. Researchers are constantly trying to find effective therapeutics for patients. The upcoming new precision therapies may hold the key to treat incurable diseases. The use of nucleic acids and nucleic acid isolation & purification products and technologies are, therefore, very crucial for developing precision medicines.

The research and development (R&D) efforts in human genomics conducted by pharmaceutical and biotechnology companies have significantly transformed disease diagnosis and treatment development. The nucleic acid isolation and purification kits and instruments market is crucial in new drug discovery, target identification, and testing, particularly in genome editing. Substantial investments in R&D and drug discovery projects drive the competitive rivalry among companies in this space. The increasing adoption of emerging technologies for therapy development is expected to further drive market growth, with nucleic acid isolation and purification serving as a key step in manufacturing drugs and therapies through recombinant genetics. Key factors contributing to growth include the widespread use of CRISPR technology for identifying and validating therapeutics, creating improved animal testing models, and reducing the cost of research and development for drug discovery in preclinical trials.

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Nucleic Acid Isolation And Purification Market Report Highlights

• In terms of product, the kits & reagents segment dominated the market with the highest share in 2025.

• In terms of type, the DNA isolation and purification segment registered the highest market share in 2025.

• In terms of application, the drug discovery & development segment led with the highest market share of 35.11% in 2025, attributed to robust investments in pharmaceutical and biotechnology companies to develop novel drugs.

• In terms of method, the magnetic beads segment dominated the market with the highest share of 41.36% in 2025.

• In terms of end-use, the hospitals and diagnostic centers held the largest share of 38.64% in 2025, due to their wide range of applications in healthcare segments, such as genetic fingerprinting, prenatal testing, and liquid biopsies.

• North America nucleic acid isolation and purification market held the highest share of 41.29% in 2025. The presence of many market players in the region and their various initiatives is projected to drive the regional market.

Nucleic Acid Isolation And Purification Market Segmentation

Grand View Research has segmented the global nucleic acid isolation and purification market based on product, type, application, method, end-use, and region:

Nucleic Acid Isolation And Purification Product Outlook (Revenue, USD Billion, 2021 - 2033)

• Kits & reagents

• Instruments

  • Manual

  • Automatic

Nucleic Acid Isolation And Purification Type Outlook (Revenue, USD Billion, 2021 - 2033)

• DNA Isolation & Purification

  • Genomic DNA isolation & purification

  • Plasmid DNA isolation & purification

  • Viral DNA isolation & purification

  • Other

• RNA Isolation & Purification

  • miRNA isolation & purification

  • mRNA isolation & purification

  • Total RNA isolation & purification

  • Other

Nucleic Acid Isolation And Purification Application Outlook (Revenue, USD Billion, 2021 - 2033)

• Precision medicine

• Diagnostics

• Drug discovery & development

• Agriculture and animal research

• Other applications

Nucleic Acid Isolation And Purification Method Outlook (Revenue, USD Billion, 2021 - 2033)

• Column based

• Magnetic beads

• Reagent based

• Others

Nucleic Acid Isolation And Purification End-use Outlook (Revenue, USD Billion, 2021 - 2033)

• Academic research institutes

• Pharmaceutical & biotechnology companies

• Contract research organizations

• Hospitals and diagnostic centers

• Other end-use

Nucleic Acid Isolation And Purification Regional Outlook (Revenue, USD Billion, 2021 - 2033)

• North America

  • U.S.

  • Canada

  • Mexico

• Europe

  • Germany

  • UK

  • France

  • Spain

  • Italy

  • Denmark

  • Sweden

  • Norway

• Asia Pacific

  • China

  • Japan

  • India

  • South Korea

  • Australia

  • Thailand

• Latin America

  • Brazil

  • Argentina

• Middle East and Africa (MEA)

  • South Africa

  • Saudi Arabia

  • UAE

  • Kuwait

List of Key Players in the Nucleic Acid Isolation And Purification Market

• QIAGEN

• Thermo Fisher Scientific, Inc.

• Illumina, Inc.

• Danaher

• F. Hoffmann-La Roche Ltd

• Merck KGaA

• Agilent Technologies

• Bio-Rad Laboratories, Inc.

• Takara Bio Inc.

• Promega Corporation