Nucleic Acid Isolation and Purification Market Report

Nucleic Acid Isolation and Purification Market Analysis Report By Product, By Type (DNA, RNA), By Application (Drug Discovery, Oncology), By Method, By End Use, By Region, And Segment Forecasts, 2018 - 2025

  • Published Date: Sep, 2018
  • Base Year for Estimate: 2017
  • Report ID: GVR-2-68038-580-9
  • Format: Electronic (PDF)
  • Historical Data: 2014 - 2016
  • Number of Pages: 161

Industry Insights

The global nucleic acid isolation & purification market size was valued at USD 2.14 billion in 2017 and is poised to register a CAGR of 6.8% over the forecast period. Nucleic acid isolation and purification is one of the most complex and crucial achievements of modern science and technology. With declining cost of genomic sequencing and use of high throughput platforms and tools, the market is expected to register strong growth during the forecast period.

Increasing prevalence of genetic disorders, cancer, and infectious diseases globally has also played a major role in market growth. In addition, demand for genetically modified crops and fruits for consumption and genetically modified organisms for research studies has increased, further fueling demand for nucleic acid isolation and purification. Rising private and public partnerships in the life science and biotechnology industries, growing adoption of sequencing platforms for clinical diagnostics, rising genomic and enzymology-based research, and increasing R&D investments in molecular biology and precision medicines are also responsible for market growth.

Canada nucleic acid isolation & purification market

Moreover, use of nucleic acids in blood screening, detection of infectious diseases, genetic disorders, oncology, and precision medicine has spurred in the last decade. This is due to emergence of new advanced technologies that are user friendly and helpful in analyzing sample collection and obtaining accurate results.

The market is highly fragmented and competitive in nature. Factors that threaten to hinder market growth include lack of automation and skilled professionals, high price of instruments, and low penetration of this technology in emerging economies. As a result, the industry has been paving the way for new players with disruptive technologies to grow in this space. Furthermore, next-generation sequencing (NGS) technologies and easy availability of genomic data are offering high value avenues and opportunities for players.

There is growing demand in biotech and pharma companies due to rise in automation in nucleic acid isolation and purification applications for genetic testing and clinical diagnostics. A recent trend observed in the market is the shifting from being product-oriented to being service-oriented.

Products Insights

On the basis of product, the market is fragmented into kits and reagents and instruments. While kits and reagents accounted for the dominant share of over 70.0% in 2017, the instruments segment is anticipated to register the fastest growth over the forecast period.

Major players in the market such as QIAGEN, Thermo Fisher Scientific, Merck, Agilent Technologies, Bio-Rad, and Illumina have been offering these products for nucleic acid isolation and purification. Demand for these is expected to increase in the coming years thanks to technological advancements in testing methods. However, high price of instruments and false operative results of kits might hamper market growth.Increasing prevalence of infectious diseases, cancer, and genetic diseases is also anticipated to influence demand for these products over the forecast period.

Type Insights

Over the years, scientists have been able to separate and purify nucleic moieties such as mRNA, miRNA, plasmid DNA, and genomic DNA. This is helpful in studying diseases and their pathologies at a genetic level in detail, which in turn, has proved helpful in designing therapeutics and diagnostics for several life threatening diseases. The detachment, disengagement, ligation, and purification of nucleic acids has become a lot easier than before, thanks to technological advancements and increasing use of DNA/RNA sequencing.

By type, the market is bifurcated into DNA and RNA isolation and purification. DNA isolation and purification, which includes genomic DNA, plasmid DNA, viral DNA, and others, holds the dominant share in the overall market. Registering a 7.6% CAGR during the forecast period, the segment is also projected to expand at the fastest rate. The RNA segment includes MicroRNA (miRNA), messenger RNA (mRNA), total RNA, and others.

Application Insights

By application, the nucleic acid isolation & purification market is segmented into oncology, precision medicine, plant and animal research, diagnostics, drug discovery and development, and others. While drug discovery and development dominated the overall market, oncology is slated to emerge as the fastest growing segment by 2025 at a 7.81% CAGR.

Technological advances in genomics and proteomics has widened the application scope of nucleic acid-based therapeutics in the healthcare industry to include domains such as gene therapy, antisense therapy, and enzyme-based drug development. Application in prevention and treatment of diseases such as cancer, rheumatoid arthritis, diabetes, neurological diseases, and autoimmune diseases is also increasing.

Method Insights

Traditionally, nucleic acid isolation and purification methods were highly labor intensive and technical. With advancements in automation technologies, however, these methods have become more accurate and effective. By method, the market is classified into column-based, reagent-based, magnetic bead-based, and others. Among these, column-based methods accounted for the largest share in the global market in 2017.

Magnetic bead-based isolation and purification has become increasingly popular among researchers. These techniques and tools are utilized by diagnostic labs and clinics, pharmaceutical and biotech companies, scholastic research institutes, and hospitals. This segment is poised to register the fastest growth over the forecast period, exhibiting a 7.15% CAGR.

End-use Insights

By end use, the market is classified into academic research institutes, pharmaceutical and biotechnology companies, contract research organizations, and hospitals and diagnostic centers. Academic research institutes held the dominant share in the overall market, accounting for close to 34.0% in 2017.

Technological advances in genomics and computational technology has upped the adoption of nucleic acid sequencing and editing in various fields of research. The use of nucleic acids in academic research institutes has increased over the time. Introduction of highly efficient techniques related to isolation and purification of nucleic acids in healthcare has enabled easy and fast gene manipulation for various research studies, medicine development, and disease diagnosis. As a result, fields such as genetic tissue engineering, gene therapy, drug discovery, disease screening, and modeling studies have gained much prominence over the past few years.

Regional Insights

Rapidly growing biotechnological applications in various industries such as food processing, agriculture, recycling and waste management, energy and environment has been driving the growth and development of nucleic acid isolation and purification.

Global nucleic acid isolation & purification market

Currently, North America holds the largest share in the global market. Large number of technology providers, greater patient awareness, better healthcare infrastructure and facilities, and faster adoption of advanced technologies such as next-generation sequencing are factors driving this regional market. The market is also fueled by strong government support and continuous research in the field.

Asia Pacific is slated to emerge as the fastest growing regional market owing to rising healthcare expenditure, rapidly expanding economies, and increasing government financing in research projects. Growing demand for quality healthcare is also an important factor boosting this regional market.

Nucleic Acid Isolation & Purification Market Share Insights

The market is anticipated to grow significantly over the forecast period thanks to exponentially decreasing cost of genetic sequencing, ongoing development of personalized medicine and companion diagnostics, and technological advancements in methods used for isolation and purification of nucleic acids.

Major companies operating in this market include Qiagen; Danaher; Roche; Agilent Technologies; Illumina, Inc.; Thermo Fisher Scientific, Inc.; and Promega Corporation. These companies have been evolving at a fast pace owing to significant tie ups with IT, medical device, and healthcare companies.

Players are also interested in strategic agreements with global firms to expand their genomics and proteomics businesses. For instance, in August 2017, Qiagen announced its collaboration with Clinical Genomics, a privately held diagnostic tool developer. It was aimed at integrating PAXgene Blood ccfDNA sample collection and processing workflow in Clinical Genomics’ Colvera colorectal cancer recurrence assay.

Report Scope



Base year for estimation


Actual estimates/Historical data

2014 - 2016

Forecast period

2018 - 2025

Market representation

Revenue in USD Million and CAGR from 2017 to 2025

Regional scope

North America, Europe, Asia Pacific, Latin America, Middle East & Africa

Country scope

U.S., Canada, Germany, U.K., Japan, China, Brazil, Mexico, South Africa

Report coverage

Revenue forecast, company share, competitive landscape, growth factors and trends

15% free customization scope (equivalent to 5 analysts working days)

If you need specific information, which is not currently within the scope of the report, we will provide it to you as a part of customization

Segments Covered in the Report

This report forecasts revenue growth at global, regional, and country levels and provides an analysis on latest industry trends in each of the sub-segments from 2014 to 2025. For this study, Grand View Research has segmented the global nucleic acid isolation & purification market report based on product, type, application, method, end use, and region:

  • Product Outlook (Revenue, USD Million, 2014 - 2025)

    • Kits & Reagents

    • Instruments

  • Type Outlook (Revenue, USD Million, 2014 - 2025)

    • DNA  

      • Genomic DNA

      • Plasmid DNA

      • Viral DNA

      • Others

    • RNA   

      • miRNA

      • mRNA

      • Total RNA

      • Others

  • Application Outlook (Revenue, USD Million, 2014 - 2025)

    • Oncology

    • Precision Medicine

    • Diagnostics

    • Drug Discovery & Development

    • Agriculture and Animal Research

    • Others

  • Method Outlook (Revenue, USD Million, 2014 - 2025)

    • Column-based

    • Magnetic Bead-based

    • Reagent-based

    • Others

  • End Use Outlook (Revenue, USD Million, 2014 - 2025)

    • Academic Research Institutes

    • Pharmaceutical and Biotechnology Companies

    • Contract Research Organizations

    • Hospitals and Diagnostic Centers

    • Others

  • Regional Outlook (Revenue, USD Million, 2014 - 2025)

    • North America

      • U.S.

      • Canada

    • Europe

      • Germany

      • U.K.

    • Asia Pacific

      • Japan

      • China

    • Latin America

      • Brazil

      • Mexico

    • Middle East Africa

      • South Africa

Key questions answered by the report
Request for Customization

Choose License Type

Single User - $5,950
Multi User (2-5) - $6,950
Enterprise Access - $8,950

Buy Chapters or Sections

Avail customized purchase options to meet your exact research needs:

  • Buy sections of this report
  • Buy country level reports
  • Request for historical data
  • Request discounts available for Start-Ups & Universities

Why Choose Us

  • Research support

    24/5 Research support

    Get your queries resolved from an industry expert.

  • Custom research service

    Custom research service

    Design an exclusive study to serve your research needs.

  • Quality assurance

    Quality assurance

    A testimonial for service in the form of BBB "A" Accreditation.

  • BBB Rating dandb
  • Information security

    Information security

    Your personal and confidential information is safe and secure.

  • grand view research PCI DSS complaint grand view research paypal verified