Avenanthramides Market (2025 - 2033) Size, Share & Trends Analysis Report By Product (Natural, Synthetic), By End-use (Personal Care & Cosmetics, Pharmaceuticals, Animal Health), By Region (North America, Europe, Asia Pacific), And Segment Forecasts

Avenanthramides Market Summary

The global avenanthramides market size was estimated at USD 134.7 million in 2024 and is projected to reach USD 295.0 million by 2033, growing at a CAGR of 9.3% from 2025 to 2033. Demand is rising because the cosmetic, pharmaceutical, and nutraceutical sectors seek natural, evidence-backed anti-inflammatories; patents, clinical advances, and consumer preference for oat-derived actives amplify uptake, while limited raw material supply and complex extraction keep prices and margins elevated and encourage higher investment in specialized processing capacity.

Consumers favor natural, clinically validated actives; formulators value avenanthramides' dual antioxidant and anti-inflammatory profile; and pharmaceutical interest is rising as early clinical data support safety. Premiumization allows higher margins, prompting ingredient houses and biotech firms to invest in extraction, standardization, and stability research. Geographic demand concentrates in North America, Europe, and the Asia Pacific, where regulatory pathways and skincare markets are mature. Yet growth is constrained by limited oat-bran feedstock rich in avenanthramides, variable phytochemical yields across cultivars, and costly purification. Smaller suppliers face barriers to scaling GMP production, while larger players secure IP and long-term supply agreements to protect market share. Strategic R&D partnerships and contract manufacturing help de-risk supply and speed commercialization while investors back scale-up initiatives.

The rising preference for personalized beauty and nutrition solutions. Brands are reformulating products with bioactive compounds that address niche concerns such as sensitive skin, eczema, and lifestyle-related inflammation. Avenanthramides, being rare and scientifically validated, allow companies to differentiate offerings in a highly competitive environment.

Furthermore, sustainability is shaping demand. As oat cultivation is relatively low-impact compared to many other crops, avenanthramide sourcing aligns well with clean-label and eco-friendly initiatives. This sustainability narrative strengthens consumer trust, attracts premium pricing opportunities, and positions avenanthramides as an ingredient of choice in both advanced cosmeceuticals and functional health products.

Market Concentration & Characteristics

The elastomeric sealants market is characterized by moderate concentration, with a mix of global producers and specialized regional suppliers competing across construction, automotive, and industrial applications. The market is shaped by innovation in formulation technologies, with emphasis on enhanced durability, flexibility, and environmental resistance. Players focus on differentiating through performance attributes such as adhesion strength, weather resistance, and compliance with evolving environmental and safety regulations. Branding and technical support also serve as competitive levers, as customers often seek tailored solutions for specific end-use conditions.

In terms of dynamics, the market’s growth is influenced by infrastructure development, rising demand for energy-efficient buildings, and the expansion of advanced manufacturing sectors. While large multinational companies set benchmarks for quality and performance, regional producers cater to cost-sensitive applications with localized distribution strengths. The competitive environment encourages continuous R&D, partnerships with end users, and sustainability-driven innovation to align with greener construction practices and regulatory expectations.

Product Insights

The synthetic segment dominated the market and accounted for the largest revenue share of 93.3% in 2024, largely due to its broad availability, consistent performance, and cost efficiency compared to natural alternatives. Synthetic variants offer durability, chemical resistance, and scalability, making them widely adopted across industries such as construction, automotive, and packaging. Their well-established supply chains and reliable material properties continue to ensure strong demand from manufacturers seeking high-volume and dependable sealing solutions.

The natural segment is expected to grow fastest with a CAGR of 10.0% from 2025 to 2033, driven by increasing consumer preference for sustainable, eco-friendly, and bio-based solutions. Heightened awareness of environmental impacts and regulatory pressures on petrochemical-derived materials is encouraging industries to explore renewable alternatives. Advancements in bio-extraction, processing technologies, and improved performance characteristics are further supporting adoption, positioning natural sealants as attractive options in green building, healthcare, and niche industrial applications.

End-use Insights

In 2024, the personal care and cosmetics segment led the market with 57.9% of total revenue, reflecting the strong demand for bioactive ingredients that enhance skin health and appearance. Consumers increasingly favor natural, multifunctional components with proven efficacy, and avenanthramides are widely used in formulations for sensitive skin, anti-aging, and sun protection. Their anti-inflammatory and antioxidant benefits support product claims, while clean-label trends and premium skincare innovation continue to drive higher adoption in this segment.

The pharmaceuticals segment is anticipated to record the fastest growth at a 9.7% CAGR from 2025 to 2033, supported by ongoing clinical research into avenanthramides’ therapeutic properties. Early studies indicate their potential in managing inflammation-related disorders, cardiovascular health, and dermatological conditions. Rising investment in plant-based active pharmaceutical ingredients (APIs), combined with regulatory support for safer, naturally derived compounds, is encouraging wider exploration. As efficacy data strengthen, pharmaceutical applications are likely to unlock significant new growth opportunities.

Regional Insights

Asia Pacific led the market with a 43.0% revenue share in 2024, driven by large-scale cosmetic and personal care consumption in countries like China, Japan, and South Korea. Rapid urbanization, rising disposable incomes, and growing awareness of natural and functional ingredients fuel demand for premium skincare and health products. Additionally, the region benefits from a strong presence of manufacturers, lower production costs, and expanding distribution networks, further solidifying its dominance in the market.

China Avenanthramides Market Trends

China held over 90.7% revenue share of the Asia Pacific avenanthramides market. China’s market growth is fueled by rapid urbanization, increasing disposable incomes, and expanding middle-class consumer spending on premium cosmetics and healthcare products. The rising popularity of natural and functional ingredients in skincare, coupled with growing e-commerce penetration, accelerates product accessibility. Government incentives for domestic biotechnology and nutraceutical industries, along with a strong focus on localized product innovation, position China as a leading revenue contributor in the global market.

North America Avenanthramides Market Trends

North America is projected to grow at the fastest rate, with a CAGR of 9.2% from 2025 to 2033, owing to rising consumer preference for clinically validated, natural, and sustainable ingredients in personal care and pharmaceutical products. High healthcare spending, a strong focus on R&D, and early adoption of innovative bioactive compounds, including avenanthramides, create favorable market conditions. Regulatory support and the expansion of specialty ingredient suppliers also accelerate regional growth.

U.S. Avenanthramides Market Trends

The U.S. market is driven by high consumer awareness of natural and clinically validated ingredients, particularly in personal care and pharmaceutical applications. Strong R&D infrastructure, well-established regulatory frameworks, and early adoption of innovative bioactives, such as avenanthramides, support growth. Additionally, rising demand for anti-aging, sensitive skin, and wellness-oriented products, combined with premiumization trends, encourages formulators and ingredient suppliers to expand offerings in both skincare and nutraceutical segments.

Europe Avenanthramides Market Trends

Europe maintains steady growth due to stringent safety and sustainability regulations, which encourage the adoption of natural, eco-friendly ingredients. Consumers demand high-quality, certified products, particularly in personal care and cosmeceuticals. Additionally, established pharmaceutical and cosmetic industries, strong clinical research capabilities, and widespread awareness of anti-inflammatory and antioxidant benefits drive formulators to integrate ingredients like avenanthramides into premium formulations. Sustainability and clean-label trends further bolster market expansion.

Latin America Avenanthramides Market Trends

Latin America’s growth is supported by rising urbanization, increasing disposable incomes, and expanding middle-class demand for personal care and wellness products. Growing awareness of plant-based and natural ingredients, combined with a developing cosmetic and pharmaceutical industry, fuels adoption. E-commerce and retail expansion improve product accessibility, while regional ingredient suppliers are investing in local extraction and processing capabilities to meet consumer demand for high-quality bioactive compounds.

Middle East & Africa Avenanthramides Market Trends

The Middle East & Africa market benefits from increasing consumer interest in premium, natural, and skin-friendly products, particularly in GCC countries. Economic growth, rising disposable income, and a strong tourism-driven cosmetic demand boost market potential. Additionally, regional investment in healthcare infrastructure and growing awareness of natural therapeutic ingredients support adoption in pharmaceuticals and personal care. Reliance on imports and partnerships with global ingredient manufacturers also shapes market dynamics.

Key Avenanthramides Company Insights

The two key dominant manufacturers in the market are Ceapro Inc. and Cosciens Biopharma Inc.

• Ceapro Inc. is a biotechnology company focused on developing and commercializing oat-derived active ingredients, including avenanthramides. The company emphasizes scientific innovation and proprietary extraction technologies to produce high-purity bioactives for personal care, nutraceutical, and pharmaceutical applications. Its operations are driven by research and clinical validation, ensuring consistent quality and efficacy in end products. Ceapro’s strong commitment to sustainability and advanced manufacturing enables it to maintain leadership in natural bioactive ingredients, supporting innovation across multiple industries with evidence-based solutions.

• Cosciens Biopharma Inc. is a clinical-stage biopharmaceutical company dedicated to advancing plant-based bioactive compounds, with a focus on anti-inflammatory and therapeutic applications. The company leverages clinical research to validate the safety and efficacy of avenanthramides and other investigational products. Cosciens prioritizes scientific rigor and strategic partnerships to progress compounds through early-phase clinical trials. Its approach integrates modern biotechnology with natural compound development, creating opportunities for novel treatments while addressing unmet medical needs in inflammation and related health conditions.

Recent Developments

• In March 2025, Seriant partnered with COSCIENS Biopharma (NASDAQ/TSX: CSCI) to advance Avenanthramides into Phase 2a at Montreal Heart Institute, following Phase 1 success. The trial evaluates efficacy in mild to moderate inflammation with Seriant’s clinical research expertise.

• In March 2025, COSCIENS Biopharma announced successful Phase 1 trials of its oat-derived avenanthramide, showing excellent safety. The company will advance to Phase 2a efficacy studies in patients with mild to moderate inflammation at the Montreal Heart Institute.

Avenanthramides Market Report Scope

Global Avenanthramides Market Report Segmentation

This report forecasts revenue growth at global, regional, and country levels and provides an analysis of the latest industry trends in each of the sub-segments from 2018 to 2033. For this study, Grand View Research has segmented the global avenanthramides market report based on product, end-use, and region:

• Product Outlook (Revenue, USD Million; Volume, Kilotons; 2018 - 2033)

  • Natural

  • Synthetic

• End-use Outlook (Revenue, USD Million; Volume, Kilotons; 2018 - 2033)

  • Personal Care & Cosmetics

  • Pharmaceuticals

  • Animal Health

  • Other End-use

• Regional Outlook (Revenue, USD Million; Volume, Kilotons; 2018 - 2033)

  • North America

    • U.S.

    • Canada

    • Mexico

  • Latin America

    • Brazil

    • Argentina

  • Europe

    • Germany

    • UK

    • Italy

    • Spain

    • France

  • Asia Pacific

    • China

    • Japan

    • South Korea

  • Middle East & Africa

    • Saudi Arabia

    • South Africa