Cell Separation Market Size, Share & Trends Report

Cell Separation Market Size, Share & Trends Analysis Report By Product (Consumables, Instruments), By Cell Type, By Technique (Centrifugation, Surface Marker, Filtration), By Application, By End Use, By Region, And Segment Forecasts, 2021 - 2028

  • Published Date: May, 2021
  • Base Year for Estimate: 2020
  • Report ID: GVR-1-68038-707-0
  • Format: Electronic (PDF)
  • Historical Data: 2016 - 2019
  • Number of Pages: 120

Report Overview

The global cell separation market size was valued at USD 6.6 billion in 2020 and is expected to expand at a compound annual growth rate (CAGR) of 18.8% from 2021 to 2028. Cell separation plays an important role in various applications including biologics designing and development, therapeutic protein production, in-vitro diagnostics, and other research applications. The rising prevalence of chronic and infectious diseases, such as cancer and Covid-19, and continuous government initiatives to improve the biotechnology industry are the major driving factors contributing to market growth.

U.S. cell separation market size, by product, 2016 - 2028 (USD Billion)

In addition, the COVID-19 pandemic has created a lucrative opportunity for researchers to study and understand this new infectious virus, to develop treatments and diagnostic tools for it. Several pharmaceutical and biotech giants have been conducting rapid and extensive R&D activities to develop novel vaccines, therapies, and testing kits. This has significantly boosted the demand for cell separation tools in research applications.

Cell separation or isolation techniques are widely used to develop and manufacture biologics, such as monoclonal antibodies and recombinant proteins. These products have been gaining traction over the past few decades. With a substantial growth of specialty drugs and personalized medicine, the demand for biologics has been increasing. According to CAS (A division of the American Chemical Society), it was estimated that biologics will grow to USD 399.5 billion by 2025. The number of biologics registered under CAS has increased three-hundred-fold in the past few years. Also, growing regulatory convergence, technological advancements in R&D, and an increase in the number of chronic diseases have led to the growing demand for biologics. Thus, such mounting demand for biologics is anticipated to create high demand for separation solutions while manufacturing process, thus, supporting the growth of the market for cell separation.

Furthermore, the growing prevalence of chronic diseases has further increased the demand for cell separation solutions for diagnostics and research applications. According to the American Cancer Society, there are an estimated 16.9 million cancer patients/survivors in 2020. Data from the same source suggests that over 1.8 million new cases are expected to be diagnosed in the same year. According to the WHO, in 2020, 71.0 million people worldwide are suffering from chronic hepatitis C infection. According to the American Autoimmune Related Diseases Association, Inc., an estimated 50 million U.S. citizens were suffering from autoimmune diseases in 2017.

Although, cell separation instruments and related products can render accurate and effective results and have indispensable applications in the fields of disease diagnosis and scientific research. However, high prices associated with these products are one of the major factors impeding this market. In addition, cell separation techniques encompass a wide range of costs involving instruments, reagents, kits, sera, and services. The reagents used for specific applications are of high cost and cell separation setup is expensive. These factors are anticipated to limit the growth of the market during the forecast period.

Product Insights

In 2020, the consumables segment dominated the market for cell separation and accounted for the largest revenue share of 62.3%. This segment held the largest market share due to repeated purchases of consumables. In addition, rising investments in R&D by biotechnology and biopharmaceutical companies for the development of advanced biologics including monoclonal antibodies and vaccines are also driving the segment. Thus, the demand for consumables is also expected to remain high during the forecast period.

The instruments segment is estimated to exhibit a lucrative growth rate during the forecast period, due to product advancements. Technological advancement in instruments provides efficient cell separation in research, diagnostics, and therapeutics application. Thus, the industry for instruments is anticipated to witness significant growth during the forecast period. However, the high cost of instruments is expected to restrain the market growth.

Cell Type Insights

The human cell segment dominated the market for cell separation and held the largest revenue share of 44.8% in 2020. Rising focus on human and cancer research and varied applications of isolated human cells in biopharmaceuticals development, clinical trials, and research are among the major factors contributing to its largest share. Moreover, favorable reimbursement policies pertaining to personalized medicine in developed countries further boost the demand for human cell isolation.

The animal cells segment is anticipated to exhibit a lucrative growth rate during the forecast period. The growing focus of government, private, and healthcare companies on new drug discoveries and development is a key factor driving the segment growth. Drug discovery and development involve animal cells' use to examine efficacy, the pharmacokinetics of new drug molecules, and preliminary toxicity.

Technique Insights

The centrifugation segment dominated the market for cell separation and held the largest revenue share of 42.7% in 2020. This is due to the extensive usage of this technique by academic institutes, research laboratories, and biotechnology and biopharmaceutical companies. Centrifugation is one of the most important steps in cell isolation. Density gradient centrifugation and differential centrifugation are most commonly used for cell isolation. Density gradient centrifugation makes use of molecular weights of the particles to be separated, whereas differential centrifugation makes use of a lysate to break cell membranes to separate them.

The surface marker and filtration segments are expected to witness significant growth in the near future. Rising investments in manufacturing infrastructure by companies and product advancements are prime factors supporting the growth of this segment. Manufacturers are engaged in the usage of advanced filtration system surface markers for production and research processes to ensure a better quality of the end product.

Application Insights

The biomolecule isolation segment dominated the market for cell separation and accounted for the highest revenue share of 30.8% in 2020. The growing focus on the production of biopharmaceuticals, including biosimilar, monoclonal antibodies, and recombinant proteins, is the most predominant factor contributing to its highest share. Also, increasing government funding for new drug development propels the market growth.

The cancer research and stem cell research segments are projected to exhibit lucrative growth over the study period. Rising investment in cell-based research by companies and research laboratories is a key factor that can be attributed to the segment growth. Several public-private organizations are investing heavily in cancer research owing to the increasing global incidence of cancer, thus, driving the demand for innovative separation solutions.

End-use Insights

The research laboratories and institutes segment accounted for the largest revenue share of 43.9% in 2020 and is expected to hold its position throughout the study period. This can be attributed to increasing R&D initiatives by research institutions to develop novel therapies in oncology and neuroscience. The growing number of research institutes and laboratories across the globe is also anticipated to be a major driver of the segment. For instance, in April 2017, the New York Stem Cell Foundation (NYSCF) opened a new Research Institute in Manhattan, which is focused on conducting the most advanced stem cell research.

Global cell separation market share, by end use, 2020 (%)

The biotechnology and pharmaceutical companies segment exhibited significant growth over the forecast period due to increasing R&D investment by these companies for the development of new products. These companies are involved in extensive R&D activities for the development of new-generation therapeutics, which require cell separation techniques. Furthermore, increasing research activities by commercial organizations to develop efficient vaccine and therapeutics for COVID-19 are anticipated to create high demand for cell separation solutions, thereby supporting segment growth.

Regional Insights

North America dominated the cell separation market and held the largest revenue share of 38.5% in 2020. This can be attributed to well-established pharmaceutical and biotech industries, and the high adoption of technologically advanced solutions in the U.S. Furthermore, extensive research activities by research universities in the field of cell therapies have created a huge demand for cell separation solutions. In addition, the high prevalence of chronic and infectious diseases, including the outbreak of COVID-19, has led to an increase in the demand for cell separation solutions for research and clinical applications.

In Asia Pacific, the market for cell separation is projected to witness significant growth due to growing pharmaceutical and biotechnology industries in emerging economies such as China and India. In addition, growth in healthcare expenditure and increase in market penetration of major global players in key Asia Pacific countries are factors expected to drive the segment over the forecast period. Furthermore, continuous stem and gene therapy research initiatives in Japan, China, and South Korea have further boosted the demand for cell separation solutions in the region.

Key Companies & Market Share Insights

Key players are engaged in organic and inorganic growth strategies such as product development, collaborations, partnerships, mergers, and acquisitions to garner high market share. For instance, in February 2021, Thermo Fisher Scientific acquired cell-sorting assets from U.S.-based Propel Labs. As per the deal, Thermo Fisher Scientific added Propel Labs’ novel Bigfoot Spectral Cell Sorter and around 40 employees in its capabilities. Some of the prominent players in the global cell separation market include:

  • Thermo Fisher Scientific, Inc.

  • Becton, Dickinson and Company

  • Danaher

    • Beckman Coulter, Inc.

    • Cytiva

  • Terumo Corporation

  • STEMCELL Technologies Inc.

  • Bio-Rad Laboratories, Inc.

  • Merck KGaA

Cell Separation Market Report Scope

Report Attribute

Details

Market size value in 2021

USD 7.7 billion

Revenue forecast in 2028

USD 25.8 billion

Growth Rate

CAGR of 18.8% from 2021 to 2028

Base year for estimation

2020

Historical data

2016 - 2019

Forecast period

2021 - 2028

Quantitative units

Revenue in USD million and CAGR from 2021 to 2028

Report coverage

Revenue forecast, company ranking, competitive landscape, growth factors, and trends

Segments covered

Product, cell type, technique, application, end use, region

Regional scope

North America; Europe; Asia Pacific; Latin America; MEA

Country scope

U.S.; Canada; Germany; U.K.; France; Italy; Spain; Russia; Japan; China; India; South Korea; Australia; Singapore; Brazil; Mexico; Argentina; South Africa; Saudi Arabia; UAE

Key companies profiled

Thermo Fisher Scientific, Inc.; Becton, Dickinson and Company; Danaher (Beckman Coulter, Inc.; Cytiva); Terumo Corporation; STEMCELL Technologies Inc.; Bio-Rad Laboratories, Inc.; Merck KGaA

Customization scope

Free report customization (equivalent to up to 8 analyst’s working days) with purchase. Addition or alteration to country, regional & segment scope.

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Segments Covered in the Report

This report forecasts revenue growth at the global, regional, and country levels and provides an analysis of the latest industry trends in each of the sub-segments from 2016 to 2028. For the purpose of this study, Grand View Research has segmented the global cell separation market report based on product, cell type, technique, application, end use, and region:

  • Product Outlook (Revenue, USD Million, 2016 - 2028)

    • Consumables

      • Reagents, Kits, Media, and Sera

      • Beads

      • Disposables

    • Instruments

      • Centrifuges

      • Flow Cytometers

      • Filtration Systems

      • Magnetic-activated Cell Separator Systems

  • Cell Type Outlook (Revenue, USD Million, 2016 - 2028)

    • Human Cells

    • Animal Cells

  • Technique Outlook (Revenue, USD Million, 2016 - 2028)

    • Centrifugation

    • Surface Marker

    • Filtration

  • Application Outlook (Revenue, USD Million, 2016 - 2028)

    • Biomolecule Isolation

    • Cancer Research

    • Stem Cell Research

    • Tissue Regeneration

    • In Vitro Diagnostics

    • Therapeutics

  • End-use Outlook (Revenue, USD Million, 2016 - 2028)

    • Research Laboratories and Institutes

    • Hospitals and Diagnostic Laboratories

    • Cell Banks

    • Biotechnology and Biopharmaceutical Companies

  • Regional Outlook (Revenue, USD Million, 2016 - 2028)

    • North America

      • U.S.

      • Canada

    • Europe

      • Germany

      • U.K.

      • France

      • Italy

      • Spain

      • Russia

    • Asia Pacific

      • Japan

      • China

      • India

      • South Korea

      • Australia

      • Singapore

    • Latin America

      • Brazil

      • Mexico

      • Argentina

    • MEA

      • South Africa

      • Saudi Arabia

      • UAE

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