Chondroitin Sulfate Market Size, Share & Trends Analysis Report By Source (Bovine, Shark, Swine), By Application (Nutraceuticals, Pharmaceuticals), By Region (APAC, North America), And Segment Forecasts, 2024 - 2030

Chondroitin Sulfate Market Size & Trends

The global chondroitin sulfate market size was estimated at USD 1.29 billion in 2023 and is anticipated to grow at a CAGR of 4.2% from 2024 to 2030. The demand for chondroitin sulfate is projected to be driven by the rising demand for nutraceutical goods and the growing incidences of osteoarthritis. Pharmaceutical-grade chondroitin sulfate is mainly used to treat Urinary Tract Infections (UTIs), cataracts, and osteoarthritis, which is expected to fuel the overall demand for the source. In addition, it is utilized in the form of medications to lower blood sugar levels, prevent tumor spread, and promote liver function. Moreover, the general market expansion is anticipated to be aided by the increasing demand for its use in treating osteoarthritis and several other disorders.

A long chain of sugars, including glucuronic acid and N-acetylgalactosamine, make up chondroitin sulfate. Human connective tissues, cartilage, and joints all contain chondroitin sulfate in some form. Improved joint functioning results from regular chondroitin sulfate consumption. In addition, the product can be utilized in veterinary medicine and as an eye drop for dry eyes. Meat and the sector that produces it both significantly impact market demand. The market has grown due to the rising meat consumption and high demand for meat-based sources from the pet industry. Animals by sources, such as kidneys, spleen, liver, brains, and lungs, have significant nutritional value and are used in various businesses.

For instance, several countries, including Japan, China, and India, use animal glands and organs for medical purposes. Animal intestines are used to make tallow, meat meal, fertilizer, and pet food. In addition, liver extract from pigs and cattle is used as a dietary supplement and a source of vitamin B12 for treating different types of anemia. Fish waste containing too many bones or high oil content is turned into industrial sources and feed. Moreover, cartilage is used as a source of the ingredients collagen and chondroitin sulfate, which are used in various pharmaceutical, nutraceutical, cosmetic, and food sources.

The use of meat and meat sources is rising, which has resulted in more animals being killed. Given that the chondroitin source is made from cartilage collected after slaughter, this has benefited the makers of the substance tremendously. One of the most prevalent musculoskeletal conditions affecting older people is osteoarthritis. It impacts the joints, restricts motion, and causes pain. Osteoarthritis is treated with chondroitin sulfate to relieve pain, slow the progression of the condition, and alleviate osteoarthritis symptoms. It will likely become more popular as osteoarthritis becomes more common in industrialized nations like the U.S. and the UK.

Drivers, Opportunities & Restraints

Osteoarthritis is one of the most common musculoskeletal conditions among the aging population. It affects the joints, limits movements, and causes pain in that area. Chondroitin sulfate is used in the treatment of osteoarthritis to reduce pain, lessen the disease, and improve the symptoms. The increasing prevalence of osteoarthritis in developed economies, such as the U.S. and the UK, among others, is anticipated to drive the demand for chondroitin sulfate in the treatment.

According to the CDC, there will be an estimated 67 million cases of arthritis in the U.S. by 2025. As per Arthritis Research UK, over 8.3 million people are projected to suffer from knee osteoarthritis by 2035. This mounting prevalence of osteoarthritis is expected to surge the demand for chondroitin sulfate among pharmaceutical, nutraceutical, and dietary supplement manufacturers.

Chondroitin sulfate is estimated to witness high demand over the forecast period at a faster pace from the manufacturers of food and dietary supplements due to the aging population, healthcare expenditure, and growing awareness among individuals regarding self-management and preventive care. Moreover, the demand for chondroitin sulfate for its use in joint health supplements to reduce joint pain is growing with the aging population and an increase in health-conscious customers, thus contributing to its consumption in the pharmaceutical sector.

In the pet food sector, chondroitin sulfate is used as a bioactive supplement due to its several health benefits in animals. It is used as a critical ingredient in pet food products and veterinary supplements to avoid difficulties related to hip dysplasia or arthritis in animals. Chondroitin sulfate is also in demand as its consumption improves pet activity and health with better joint mobility, which is anticipated to boost the demand for the product in feed grade.

Chondroitin sulfate is present in the cartilages of animals such as bovine, shark, poultry, and swine. Extraction of chondroitin sulfate from these sources is quite a complicated process owing to the adulteration of the product during removal, which can later be harmful for consumption. As a result, this extraction process is capital intensive, as maintaining the quality and purity of the final product is necessary.

The extraction process of several components from cartilage, such as sodium chondroitin sulfate, requires high capital. The product is also expected to undergo several purification processes to minimize adulteration. Moreover, fluctuating cartilage prices are anticipated to increase the production costs of chondroitin sulfate, which is further expected to hamper the market's growth.

Market Concentration & Characteristics

The global chondroitin sulfate market is concentrated, with several companies focusing on regional markets. TSI Group Ltd., Hebei SanXin Industrial Group, Sino Siam Biotechnique Company Ltd., and Bio-gen Extracts Pvt. Ltd. are key players in the market. Most of the companies have established exclusive agreements with distributors to cater to end-users.

Key manufacturers in developed economies, such as the U.S., France, Germany, and the UK, supply the majority of the chondroitin sulfate to key players in the nutraceutical and pharmaceutical sectors. The growth in this market can be attributed to the prevalence of osteoarthritis and the increasing consumption of dietary supplements.

The competitive rivalry in the market is high owing to increasing investments in R&D for product innovation and improving product efficiency. High competition concerning the final prices of the product and shifting focus of manufacturers on increased utilization of natural extracts thus indicates high competitive rivalry.

Source Insights

“The synthetic segment is expected to witness growth at 12.4% CAGR”

The bovine source segment dominated the global industry in 2023 and accounted for the maximum share of more than 37.9% of the overall revenue. This is attributed to the increased source usage in various application industries, including pharmaceutical, personal care & cosmetics, and nutraceuticals globally. Pharmaceutical, nutraceutical, and animal feed industries are among the few sectors that use chondroitin sulfate made from sharks. Sharks are currently regarded as endangered, which may impede the sector's expansion.

The capacity to treat persons with HIV, arthritis, and gut inflammation makes the shark-derived product the preferred form, and this preference is anticipated to further fuel demand during the projection period. Synthetic sodium chondroitin sulfate is produced utilizing a two-stage fermentation-based technique. Because animal cartilage is not used in the process, there is a low risk of contamination and adulteration. Low sourcing costs are also a result of the extraction process's simplicity. In addition, it can be used as an alternative by vegetarians and other people with dietary and religious limitations. Thus, its demand is anticipated to increase in Asian and Middle Eastern nations.

Application Insights

“Nutraceutical segment is expected to witness growth at 4.8% CAGR”

The nutraceutical segment dominated the industry in 2023 and accounted for the largest share of 36.1% of the overall revenue. Its high share is attributed to the rising investments in the sector due to the need to develop new and more effective dietary supplements. In the nutraceutical sector, it is frequently used as a dietary supplement to treat osteoarthritis and joint discomfort. They are ingested to soothe arthritis pain and to fortify bones, cartilage, and joints. The source is classed considering the national laws of each nation.

In the United States, it is prescribed as a dietary supplement and combined with glucosamine to relieve arthritic pain. Rising dietary supplement consumption is predicted to fuel market expansion in nations like the U.S. Furthermore, animal feed additives often contain glucosamine hydrochloride and chondroitin sulfate. To improve joint health and mobility, pet diets, particularly those for dogs and cats, contain chondroitin sulfate from bovine sources. The medicine also treats hip dysplasia, osteoarthritis, intervertebral disc disease, and chronic discomfort from patellar luxation and intervertebral disc disease.

Regional Insights

“Asia Pacific segment is expected to witness growth at 4.7% CAGR”

The chondroitin sulfate market in North America dominated the global industry with a revenue share of 36.2% in 2023 due to the rising pharmaceutical sector in the United States, along with the FDA’s approval for the use of goods containing sodium chondroitin sulfate. In addition, the demand is expected to be fueled by factors, such as the increasing prevalence of osteoarthritis, rising usage of cholesterol treatment, cataract surgery, and formulations for eye drops. The pharmaceutical, cosmetics, culinary, pet food, and veterinary industries are among the few industries in Europe that use chondroitin sulfate. In dietary supplements, it is used as an alternative therapy to treat osteoarthritis.

U.S. Chondroitin Sulfate Market Trends

The U.S. chondroitin sulfate market is expected to witness rapid growth due to the rising prevalence of osteoarthritis in the country. Chondroitin sulfate sourced from bovine is preferred in the country for treating osteoarthritis, HIV, heart diseases, and cholesterol. The increasing geriatric population and the inclination of consumers toward dietary supplements are anticipated to boost the domestic market growth.

Europe Chondroitin Sulfate Market Trends

The chondroitin sulfate market in Europe is growing significantly due to the increased use of sodium chondroitin sulfate-infused pharmaceuticals and nutraceuticals, which will boost the market in Europe. Chondroitin sulfate is generally used to treat osteoarthritis, relieve joint pain, treat heart problems & excessive cholesterol, and prepare eye drops. The growing aging population in emerging nations like China and India has led to a high frequency of osteoarthritis and other joint health-related problems. The pharmaceutical industry in the Asia Pacific is expected to see increased demand for sources due to the prevalence of osteoarthritis and its growing inclusion in the treatment of various medical disorders.

The Germany chondroitin sulfate market will witness rapid growth. The product is majorly used to treat osteoarthritis due to the high disease occurrence rate in the country. It is also used in several food products and dietary supplements. The rising number of patients diagnosed with osteoarthritis and increasing product demand from the nutraceutical sector is anticipated to drive the country’s market growth.

The chondroitin sulfate market in Spain will witness rapid growth. The product is explicitly used in nutraceutical products and dietary supplements. Spain has emerged as a key market for R&D activities in new nutraceutical products. Manufacturers in the country focus on product innovation and thus spend a lot on R&D activities. The development of nutraceutical products infused with chondroitin sulfate is anticipated to drive the market further over the forecast period.

Asia Pacific Chondroitin Sulfate Market Trends

The Asia Pacific chondroitin sulfate market is expected to witness the fastest CAGR of 4.7% from 2024 to 2030. This is attributed to the expansion of end-use industries, including nutraceutical, pharmaceutical, personal care, and cosmetics. Increasing production of chondroitin sulfate in the region and increasing exports from key countries, such as China and Japan, are anticipated to contribute to the market growth.

The chondroitin sulfate market in China is fragmented in nature with the presence of over 200 manufacturers. The raw material is a prominent cost-driving factor, accounting for a major share of the final product price. However, high product exports from China to developed countries like the U.S. and some European countries are expected to drive the market further. The U.S. Food and Drug Administration (FDA) recognized "oversulfated chondroitin sulfate" as a pollutant in heparin originating from the country, which is anticipated to hamper the market growth in China.

The Japan chondroitin sulfate market isestimated to witness significant growth. The product is widely used in the pharmaceutical and cosmetic sectors. The growing geriatric population has led to a surge in the prevalence of osteoarthritis in the country. Chondroitin sulfate reduces the swelling and pain associated with osteoarthritis and helps recover knee function. It is also used in eye drops, energy foods, and metabolic drugs, which are projected to drive product demand in the country.

Central & South America Chondroitin Sulfate Market Trends

The chondroitin sulfate market in Central & South America will witness rapid growth owing to the rising demand for medicines and dietary supplements in key countries, such as Brazil and Argentina. Bovine-derived chondroitin sulfate is preferred in the region as key countries are involved in beef farming and domestic consumption of chondroitin sulfate products. Furthermore, the high prevalence of osteoarthritis and rising consumer awareness regarding a healthy diet are anticipated to drive product demand. Carbosynth is a prominent manufacturer and supplier of chondroitin sulfate in the region.

The Brazil chondroitin sulfate market will witness rapid growth. The product is majorly used in the production of pharmaceutical and nutraceutical products. The development of the pharmaceutical industry in the country can be attributed to innovation, impressive local pharmaceutical products' production, and undertaking public policies that provide access to medicines. The country's well-educated youth are inclined toward consuming dietary supplements to boost immunity and protein intake. These factors are anticipated to drive product demand in the country.

Middle East & Africa Chondroitin Sulfate Market Trends

The chondroitin sulfate market in the Middle East and Africa will witness rapid growth. The product is used in the pharmaceutical sector to treat patients suffering from osteoarthritis. Most of the region's aging population has experienced a few symptoms of osteoarthritis, which can make daily activities difficult. Rising awareness of pharmaceutical manufacturers regarding the effectiveness of chondroitin sulfate in the treatment of osteoarthritis is contributing to the market growth in the region.

The South Africa chondroitin sulfate market will witness rapid growth in the coming years. Knee osteoarthritis has been a significant concern in the urban part of South Africa over the past decade, as over 50% of the aging population is prone to it. Chondroitin sulfate is primarily used in pharmaceutical, nutraceutical, and animal feed applications. Increased consumption of dietary supplements to boost the immune system, along with the growth of the pharmaceutical sector in the country, is anticipated to drive the product demand.

Key Companies & Market Share Insights

Due to the presence of various manufacturers, particularly in China, the industry is highly fragmented. Due to the rising R&D expenditures for source innovation and improving source efficiency, there is intense competition in the industry. High competitive rivalry is indicated by high competitiveness in the source’s final prices and producers’ shifting priorities toward greater use of natural extracts. Sustainable raw material sourcing and effective sourcing techniques are the main areas of concern for manufacturers. Companies are turning to cartilage with a high-purity concentration to make the sources. For example, ZPD provides multiple grades containing 20%, 40%, and 80% sodium chondroitin sulfate and other forms of sodium chondroitin sulfate components that are consistent with regulations for pet food makers.

• TSI Group Ltd. manufactures and distributes innovative and functional health products. It develops ingredients and finished dosage forms for human consumption, including tablets, stick packs, powders, and two-piece hard capsules. The ingredients are backed by an inclusive technical dossier of clinical studies' safety information and technical specifications. It has custom manufacturing solutions and expertise in formulation development. The company follows vertical integration, which turns proprietary and conventional raw materials into profitable solutions. It offers chondroitin sulfate-based supplements, pharmaceutical products, and food-grade products under the PUREFLEX brand

• Qingdao Wan Toulmin Biological Products Co., Ltd. specializes in developing, manufacturing, and distributing high-quality chondroitin sulfate and collagen peptides-based products worldwide. The company has adopted a quality management system that complies with ISO and CGMP 9001. It is fully integrated and involved in purchasing, production, warehousing, documentation, quality control, other functional departments, and resources quality assurance of products

Chondroitin Sulfate Market Report Scope

Report Attribute	Details
Market size value in 2024	USD 1.33 billion
Revenue forecast in 2030	USD 1.65 billion
Growth rate	CAGR of 4.2% from 2024 to 2030
Historical data	2018 - 2023
Forecast period	2024 - 2030
Report updated	July 2024
Quantitative units	Revenue in USD million, volume in tons, and CAGR from 2024 to 2030
Report coverage	Revenue forecast, company ranking, competitive landscape, growth factors, and trends
Segments covered	Source, application, and region
Regional scope	North America; Europe; Asia Pacific; Central & South America; Middle East & Africa
Country scope	U.S.; Canada; Mexico; Germany; UK; France; Italy; Spain; China; Japan; India; South Korea; Australia; Taiwan; Brazil; Argentina; Chile; Colombia; South Africa
Key companies profiled	TSI Group Ltd.; Qingdao Wan Toulmin Biological Sources Co., Ltd.; Hebei SanXin Industrial Group; Bioiberica SAU; Sigma Aldrich, Inc.; ZPD; Sino Siam Biotechnique Company Ltd; BRF; Bio-gen Extracts Pvt. Ltd.; Seikagaku Corp.
Customization scope	Free report customization (equivalent up to 8 analysts working days) with purchase. Addition or alteration to country, regional & segment scope
Pricing and purchase options	Avail customized purchase options to meet your exact research needs. Explore purchase options

 

Global Chondroitin Sulfate Market Report Segmentation

This report forecasts revenue and volume growth at global, regional, and country levels and provides an analysis of the latest trends in each of the sub-segments from 2018 to 2030. For this study, Grand View Research has segmented the chondroitin sulfate market report based on source, application, and region:

• Source Outlook (Volume, Tons; Revenue, USD Million, 2018 - 2030)

  • Bovine

  • Swine

  • Poultry

  • Shark

  • Synthetic

• Application Outlook (Volume, Tons; Revenue, USD Million, 2018 - 2030)

  • Nutraceuticals

  • Pharmaceuticals

  • Animal Feed

  • Personal Care & Cosmetics

  • Other Applications

• Regional Outlook (Revenue, USD Million; Volume, Tons; 2018 - 2030)

  • North America

    • U.S.

    • Canada

    • Mexico

  • Europe

    • Germany

    • UK

    • France

    • Italy

    • Spain

  • Asia Pacific

    • China

    • Japan

    • India

    • South Korea

    • Australia

    • Taiwan

  • Central & South America

    • Brazil

    • Argentina

    • Chile

    • Colombia

  • Middle East and Africa

    • South Africa