Chromatography Resins Market Size, Share & Trends Report

Chromatography Resins Market Size, Share & Trends Analysis Report By Product (Natural, Synthetic), By Technique (Ion exchange, Affinity, Hydrophobic Interaction), By End Use, By Region, And Segment Forecasts, 2020 - 2027

  • Published Date: Jun, 2020
  • Base Year for Estimate: 2019
  • Report ID: GVR-4-68039-386-6
  • Format: Electronic (PDF)
  • Historical Data: 2016 - 2018
  • Number of Pages: 155

Report Overview

The global chromatography resins market size was valued at USD 1.9 billion in 2019 and is projected to grow at a compound annual growth rate (CAGR) of 7.8% from 2020 to 2027. Growth in the market can be attributed to the mounting demand for the product from pharmaceutical sector, for drug discovery, with the development of novel resins, which have better productivity in comparison to conventional resins. Chromatography technique played a critical role in saving millions of lives around the world since the outbreak of the deadly Ebola virus in 2015, which claimed over 10,000 lives in West Africa. Chromatography proved to be extremely useful in determining more effective antibodies in neutralizing the Ebola virus.

U.S. chromatography resins market size

Chromatography is also extensively used in other end-use segments such as water and environmental agencies, and food and beverage. It is used in a large range of applications; it is mainly used to separate a complex mixture and can separate compounds based on their molecular weight, size, ionic mobility, boiling point, and polarity. Chromatography is widely used in biotechnology and in food and beverage industries for testing chromatography resin purposes.

The European Medical Agency’s (EMA) initiative to maintain drug and food safety is estimated to drive the market for chromatography resins. Furthermore, low-cost product manufacturers based in the Asia Pacific, especially China and India, are expected to grab a sizable market share. The industry is expected to register growth opportunities in the emerging markets of China and India, where pharmaceutical companies are preferring chromatography techniques over other separation techniques.

In the midst of COVID-19 pandemic, chromatography resin manufacturers such as Avantor, TriAltus Biosciences, and Purolite have taken initiatives and are heavily engaged in R&D activities for product development. For instance, TriAltus Biosciences has developed protein purification technology (novel CL7/Im7 system) to aid the providence cancer institute in COVID-19 vaccine development. Researchers are able to isolate and purify spike protein with higher yields using such technology.

Product Insights

In 2019, natural resins dominated the product segment and accounted for the largest revenue share of 51.8% in 2019, as the product is widely used in size exclusion and paper chromatography in several end-use industries. Demand for the natural resin is growing in several end-use industries on account of its low cost and high functionality. Natural resins are further categorized into agarose, and dextran, among others.

However, synthetic resin is expected to emerge as the fastest growing product in the chromatography resin market over the forecast period. Recent improvements in the production of synthetic resin are projected to revolutionize the industry and boost the segment in the market in the near future. Synthetic resin is mainly used in ion exchange chromatography, which is used in food and beverage, chemicals, pharmaceuticals industry, petrochemicals, sugar production, water treatment, and softening of industrial water.

Technique Insights

Ion Exchange accounted for the largest revenue share of 41.6% in 2019, owing to the rapid growth in drug discovery activities in emerging and developed countries. Increasing emphasis on drug discovery processes by major pharmaceutical companies is expected to fuel demand for ion exchange chromatography resin. The rise in CRO (contract research organization) and CMO (contract manufacturing organization) is expected to boost the chromatography resin market, especially the demand for ion exchange chromatography resin.

Affinity is another dominant technique on account of the high demand for nucleic acid purification and protein purification processes. Increasing the use of monoclonal antibodies for therapeutic purposes is expected to propel the demand for affinity resin. Hydrophobic interaction chromatography (HIC) resin is gradually more utilized in the removal of misfolded proteins, protein aggregate removal, and purification of monoclonal antibodies.

End-use Insights

Pharmaceutical accounted for the largest revenue share of 87.4% in 2019 owing to the huge consumption of resin in pharmaceutical processes to prepare extremely pure materials in large quantities and to inspect the cleansed compounds for contamination. Furthermore, increasing usage of monoclonal antibodies in critical therapeutic areas, including autoimmune diseases, oncology, and tuberculosis is anticipated to trigger product demand.

Global chromatography resins market share

The food and beverage segment emerged as a prominent end-use segment in 2019, in consequence of mounting consumption of the product in quality control methods. Additionally, growing consumer awareness concerning the safety and quality of food and beverage products is encouraging the manufacturers to comprehensively act in accordance with rules and regulations commenced by food regulatory authorities. This in turn is predicted to boost the product consumption from the food and beverage sector over the forecast period.

Regional Insights

North America accounted for the largest revenue share of 33.3% in the chromatography resin industry in 2019. The region is expected to witness a steady growth rate of 7.6% in terms of revenue from 2020 to 2027. Growth in the pharmaceutical sector, along with the increasing healthcare expenditure, is anticipated to remain a key factor driving the market for chromatography resins in this region. In addition to high healthcare spending and the presence of global pharmaceutical market leaders in the U.S. is also a key driver of the market in the region.

The expansion of pharmaceutical companies in North America has been underway for several years and has grown at a brisk pace, resulting in exponential demand for ion exchange chromatography resins. The major driver for the market in North America is the growing demand for drug discovery to combat diseases all around the world such as Zika and Ebola. Rising interest in the utilization of monoclonal antibodies in key therapeutic areas is anticipated to fuel the product demand in the region.

The increasing number of pharmaceutical companies in emerging markets such as China and India is anticipated to be the major driving force fostering industry growth in the Asia Pacific. The growing presence of major pharmaceutical companies such as Merck KGaA and GE Healthcare is also expected to boost the market for chromatography resins in countries like China and India. Major manufacturers are shifting their production base to developing regions such as China and India, thereby driving market growth in the region.

Key Companies & Market Share Insights

Most of the companies in the market for chromatography resins are vertically integrated across the value chain and are engaged in both forward and backward integration. Therefore, companies such as Danaher Corp., W.R. Grace who initially manufactured chromatography resin have also started supplying their final products to the customers in order to maximize profit and expand their market footprint.

Growing demand for a quality product, which is more productive, along with the popularity of technologies applied in its production, is pushing manufacturers to continuously engage in innovation and driving them to take necessary steps to maintain and heighten the standard of their products. Manufacturers are also looking forward to integrating their operations across the supply chain to retain the customers. Some of the prominent players in the chromatography resins market include:

  • Merck KGaA

  • Bio-Rad Laboratories, Inc.

  • GE Healthcare Lifesciences

  • Thermo Fisher Scientific, Inc.

  • Purolite

  • W. R. Grace & Co.-Conn.

  • Mitsubishi Chemical Corporation

  • Tosoh Corporation

  • Danaher

Chromatography Resins Market Report Scope

Report Attribute


Market size value in 2020

USD 2.1 billion

Revenue forecast in 2027

USD 3.5 billion

Growth Rate

CAGR of 7.8% from 2020 to 2027

Base year for estimation


Historical data

2016 - 2018

Forecast period

2020 - 2027

Quantitative units

Volume in thousand liters, revenue in USD million, and CAGR from 2020 to 2027

Report coverage

Revenue forecast, company ranking, competitive landscape, growth factors, and trends

Segments covered

Product, technique, end use, region

Regional scope

North America; Europe; Asia Pacific; South America; MEA

Country scope

U.S.; Canada; Mexico; Germany; U.K.; France; Italy; China; India; Japan; South Korea; Brazil; Argentina; Saudi Arabia; South Africa

Key companies profiled

GE Healthcare Lifesciences; Tosoh Corporation; Thermo Fisher Scientific; Merck KGaA;     Bio-Rad Laboratories, Inc.; Purolite; W. R. Grace & Co.-Conn. ; Mitsubishi Chemical Corporation; Danaher

Customization scope

Free report customization (equivalent up to 8 analyst’s working days) with purchase. Addition or alteration to country, regional & segment scope.

Pricing and purchase options

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Segments Covered in the Report

This report forecasts revenue growth at global, regional, and country levels and provides an analysis of the latest industry trends in each of the sub-segments from 2016 to 2027. For the purpose of this report, Grand View Research has segmented the global chromatography resins market on the basis of product, technique, end use, and region:

  • Product Outlook (Volume, Thousand Liters; Revenue, USD Million, 2016 - 2027)

    • Natural

      • Agarose

      • Dextran

      • Others

    • Synthetic

      • Silica

      • Polystyrene

      • Others

  • Technique Outlook (Volume, Thousand Liters; Revenue, USD Million, 2016 - 2027)

    • Ion exchange

    • Affinity

    • Hydrophobic interaction

    • Size exclusion

    • Others

  • End-use Outlook (Volume, Thousand Liters; Revenue, USD Million, 2016 - 2027)

    • Pharmaceutical

      • Drug Discovery

      • Drug Production

    • Water and Environmental Agencies

    • Food & Beverage

    • Others

  • Regional Outlook (Volume, Thousand Liters; Revenue, USD Million, 2016 - 2027)

    • North America

      • U.S

      • Canada

      • Mexico

    • Europe

      • Germany

      • U.K.

      • France

      • Italy

    • Asia Pacific

      • China

      • India

      • Japan

      • South Korea

    • Central & South America

      • Brazil

      • Argentina

    • Middle East & Africa

      • Saudi Arabia

      • South Africa

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