GVR Report cover Chromatography Resin Market Size, Share & Trends Report

Chromatography Resin Market Size, Share & Trends Analysis Report By Product (Natural, Synthetic), By Technique (Ion Exchange), By End-use (Pharmaceutical), By Region, And Segment Forecasts, 2023 - 2030

  • Report ID: GVR-4-68039-386-6
  • Number of Pages: 145
  • Format: Electronic (PDF)

Report Overview

The global chromatography resin market size was valued at USD 2.32 billion in 2022 and is projected to grow at a compound annual growth rate (CAGR) of 6.9% from 2023 to 2030. The growth in this market is attributable to growing demand for chromatography technique from pharmaceutical, chemical, food & beverage, and other industries. High investments for R&D in the industry has propelled the development of several products, which have resulted into improved productivity compared to conventional products. Chromatography resin is among one of the examples of evolving industry dynamics. It has gained a considerable market share in the recent years across several end-use industries owing to its high accuracy and ease of use.

U.S. chromatography resin market size and growth rate, 2023 - 2030

The U.S. is expected to remain a major consumer in the industry as most of the pharmaceutical companies are based in the U.S. This region has seen a strong growth due to focused government spending on research and development. The rise in disposable income has also directly translated into increased spending on essential and preventive healthcare services, thereby boosting the product consumption.

Increasing demand for therapeutic antibodies for treating patients is also a major driver that is triggering the industry growth. Shifting trend toward the replacing conventional separation techniques, such as distillation and filtration using chromatography is also driving innovation for the product use in numerous new segments.

The global chromatography resin market is oligopolistic in nature. The top players hold more than 60% share while regional players have a stronghold over the remaining share. The pricing and various other strategic initiatives of the market depend on the top market players. To sum up, since there are only a few firms in the market, they may have significant market power, which means they can control the prices of goods and services. This can limit competition, as smaller firms may not be able to enter the market and compete effectively.

Type Insights

Natural segment dominated the market with a revenue share of more than 51% in 2022. This high share is attributable to an increased consumption of naturally derived product, wide utilization in size chromatography, and paper chromatography in several industrial applications.

Natural resin consumption in North America is largely dominated by the U.S. on account of the presence of several global pharmaceutical giants. Expanding pharmaceutical and biomedical sectors because of the rise in healthcare expenditure and increasing demand from F&B sector are key drivers for the market in North America. Additionally, government allocation of funds in R&D of more productive chromatography resin is anticipated to further drive natural product demand in various applications and end uses in North America.

Furthermore, synthetic resin is segment is anticipated to grow at a faster pace owing to its growing utilization in ion exchange chromatography, which is used in F&B industry, chemicals, pharmaceuticals, petrochemicals, sugar production, water treatment, and softening of industrial water. Synthetic resin is increasingly being used instead of natural resin to increase production figures.

Technique Insights

Ion exchange technique segment dominated the market with a revenue share of over 42% in 2022. This high share is attributable to increasing emphasis on drug discovery processes by major pharmaceutical companies and CROs (contract research organization).

Synthetic resin is majorly used in ion exchange chromatography, which is used in F&B industry, chemicals, pharmaceuticals, sugar production, petrochemicals, water treatment, and softening of industrial water. Synthetic resin is increasingly used instead of natural resin to increase production figures.

Furthermore, affinity emerged as the second largest technique segment accounting for over 25% overall market share. The rise in the use of monoclonal antibodies, demand for protein purification and nucleic acid purification processes are the major factors responsible for propelling the affinity resin market.

End-use Insights

Pharmaceutical & biotechnology dominated the market with a revenue share of over 83% in 2022. Its high share is attributable to owing to high consumption of the resins in pharmaceutical processes to produce extremely pure materials in large quantity and to examine the purified compounds for contamination.

Global chromatography resin market share and size, 2022

Moreover, growing use of monoclonal antibodies in critical therapeutic areas such as oncology, tuberculosis, and autoimmune diseases is likely to drive demand for chromatography resin. The increasing number of contract manufacturing organizations (CMOs) and contract research organizations (CROs) in the pharmaceutical sector is anticipated to drive the product demand.

Furthermore, the ion exchange technique is one of the most creative and active fields in the food and beverages industry, which also plays a vital role in the growth of the food industry. The food & beverages end use segment is anticipated to be the fastest growing end use segment owing to the increasing strict guidelines issued by food regulatory authorities all over the world.

Regional Insights

North America region dominated the market with a revenue share of more than 33% in 2022. This high share is attributed to the growing demand for drug discovery to control diseases all around the world such as Ebola, Zika, and others. Growing interest in the use of monoclonal antibodies in therapeutic areas is also expected to fuel the North America.

The U.S. is the major consumer of the product in North America accounting for more than 92% of the market in 2022. The country offers a premier scope for chromatography resin on account of its highly developed pharmaceutical industry and growing use in end-use applications, combined with the presence of a highly skilled workforce and growing R&D initiatives to encourage innovative product application.

Chromatography Resin Market Trends, by Region, 2023 - 2030

Europe is home to major manufacturers such as Merck KGaA. The European Union’s initiatives such as the Innovative Medicines Initiative (IMI), which aims to speed up the development of better and safe medicines, have given a major boost to the chromatography resin demand in the region.

Germany is the biggest consumer of chromatography resin in Europe, owing to the significant presence of research and development facilities of global pharmaceutical companies. The region is increasingly exporting medicines and related products to neighboring countries as well as other economies around the world.

Major Asia Pacific countries including China, India, Japan, and others are expected to witness high economic growth over the forecast period. The growing government support to domestic manufacturing is likely to boost regional production levels and reduce the dependence on imports, which is expected to present lucrative opportunities for global manufacturers.

Key Companies & Market Share Insights

The chromatography resin market is not a consolidated but a diversified with the presence of both multinational and local players. Key players such as Thermo Fisher, Merck, Bio-Rad, and GE Healthcare have a wide-ranging product portfolio, extensive distribution network, and high degree of operational integration. The major players in chromatographic resin market are investing extensively in R&D, which has led to the invention of several innovative products that can be utilized across previously niche market. For instance, Bio-Rad Laboratories, Inc. launched an innovative EconoFit Low-Pressure Prepacked Chromatography resin pack to support resin screening experiments.

Other chromatographic resin producers, such as Tosoh Corporation, also occupy significant share in the chromatography resin market. These companies are also actively engaged in mergers and acquisitions to improve their standing in the market. Such strategies are only serving to boost industry competitiveness and improve the company’s position in the overall market. Some prominent players in the global chromatography resin market include:

  • Merck KGaA

  • Bio - Rad Laboratories, Inc.

  • Thermo Fisher Scientific


  • Purolite


  • Mitsubishi Chemical Holdings Corporation.

  • Danaher

Recent Developments

  • In June 2022, Bio-Rad Laboratories, Inc. launched the EconoFit Low-Pressure Prepacked Chromatography Column Packs. These packs cater to the specific needs of customers engaged in protein purification workflow development, providing a versatile selection of prepacked resin columns, including mixed-mode, cation, and anion exchange resins, as well as a dedicated pack for His-tag protein purification, streamlining resin screening experiments

  • In May 2021, Purolite entered a strategic partnership with PharmNXT Biotech aiming to expand its market presence in South Korea and Singapore. This collaboration enabled the introduction of Purolite's Praesto agarose-based Protein A and Ion Exchange chromatography resins to cater to the specific needs of customers in these regions

Chromatography Resin Market Report Scope

Report Attribute


Market size value in 2023

USD 2.47 billion

Revenue forecast in 2030

USD 3.94 billion

Growth rate

CAGR of 6.9% from 2023 to 2030

Base year for estimation


Historical data

2018 - 2021

Forecast period

2023 - 2030

Quantitative units

Revenue in USD million, volume in thousand liters and CAGR from 2023 to 2030

Report coverage

Revenue forecast, company ranking, competitive landscape, growth factors, and trends

Segments covered

Type, technique, end-use, region

Regional scope

North America; Europe; Asia Pacific; Central & South America; Middle East & Africa

Country scope

U.S.; Germany; U.K.; France; China; India; Japan; South Korea

Key companies profiled

Merck KGaA ; Bio - Rad Laboratories; Inc.; Thermo Fisher Scientific; WIPRO GE HEALTHCARE PVT LTD; Purolite; GRACE; Mitsubishi Chemical Holdings Corporation; Danaher

Customization scope

Free report customization (equivalent up to 8 analysts working days) with purchase. Addition or alteration to country, regional & segment scope.

Pricing and purchase options

Avail customized purchase options to meet your exact research needs. Explore purchase options


Global Chromatography Resin Market Report Segmentation

This report forecasts revenue growth at global, regional, and country levels and provides an analysis on the latest industry trends in each of the sub-segments from 2018 to 2030. For this study, Grand View Research has segmented the global chromatography resin market report based on type, technique, end-use, and region:

Global Chromatography Resin Market Report Segmentation

  • Type Outlook (Revenue, USD Million; Volume, Thousand Liters, 2018 - 2030)

    • Natural

    • Synthetic

    • Inorganic

  • Technique Outlook (Revenue, USD Million; Volume, Thousand Liters, 2018 - 2030)

    • Ion Exchange

    • Affinity

    • Hydrophobic Interaction

    • Size Exclusion

    • Others

  • End‑use Outlook (Revenue, USD Million; Volume, Thousand Liters, 2018 - 2030)

    • Pharmaceutical & Biotechnology

    • Food & Beverage

  • Regional Outlook (Revenue, USD Million; Volume, Thousand Liters, 2018 - 2030)

    • North America

      • U.S.

    • Europe

      • Germany

      • U.K.

      • France

    • Asia Pacific

      • China

      • India

      • Japan

      • South Korea

    • Central & South America

    • Middle East & Africa

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