Circulating Tumor Cells (CTC) Market Size, Share & Trends Report

Circulating Tumor Cells (CTC) Market Size, Share & Trends Analysis Report By Technology (Detection, Enrichment), Application (Cancer Stem Cell Research, EMT Biomarkers Development), And Segment Forecasts, 2019 - 2025

  • Published Date: Apr, 2019
  • Base Year for Estimate: 2018
  • Report ID: 978-1-68038-287-7
  • Format: Electronic (PDF)
  • Historical Data: 2014 - 2017
  • Number of Pages: 138

Industry Insights

The global Circulating Tumor Cells (CTC) market size was valued at USD 6.61 billion in 2018 and is expected to register a CAGR of 15.0% during the forecast period. Advancements in biomedical imaging and bioengineering technology is the major factor propelling the market growth. Imperative role of genomics and translational research in the development of methods that can enhance detection, enumeration, and analysis of CTC in patient specimens is attributed to boost the market growth.

Rising adoption of personalized medicine and companion diagnostic options for complete eradication of cancer from infection site is anticipated to drive the market. In addition, growing need for oncology screening, diagnosis, and therapy monitoring to determine patient’s health is anticipated to influence the sector growth in the years to come.

Japan Circulating Tumor Cells (CTC) enrichment methods market

Biological investigation of CTCs helps oncologist in gaining insights into tumor development mechanism, thereby enhancing diagnosis, serial sampling, therapeutic manipulation, and understanding resistant cancer profiles. Projects involved in biotechnology sector for trouble shooting the problems faced during CTC analysis are likely to support the development of novel methodologies, which, in turn, is expected to drive market over the forecast period.

Detection tests in development pipeline or in process of patent filing, application, and review are anticipated to augment the growth further. For instance, CTC scope system is a pipeline product by Advanced Cell Diagnostics, a privately held oncology-related company in U.S.

Technology Insights

Key technologies analyzed in this study include methodologies used for CTC enrichment, detection, and analysis. The CTC enrichment segment accounted for over 45.0% of the global market share and it is anticipated to maintain its dominance over the forecast period. This growth can be attributed to extensive usage of the methods as a result of wide scope of applications in oncology research. Presence of several methods based on different physical and electrochemical properties of CTCs for their enrichment also boosts the segment growth.

Advent of technologically advanced products, for example, novel microfluidic chip that e1nables the capture of CTC clusters, is also expected to boost the demand. Complete commercialization of cluster chips and other such products are further expected to fuel demand over the forecast period. Usage of cluster chip technology for studying CTC clusters is expected to help oncologists understand tumor metastases. Thus, such research incentives are also expected to propel the market development over the next few years.

Application Insights

Cancer stem cells research led the market in 2018, in terms of demand as well as revenue generation owing to the active participation of prominent entities, such as U-M Comprehensive Cancer Center and Institute of Stem Cell Biology and Regenerative Medicine in R&D activities. They are also involved in the study of several cancer types, such as breast, adrenal, colon, melanoma, myeloma, prostate, pancreatic, lung, nervous, thyroid, and leukemia.

Global Circulating Tumor Cells (CTC) enrichment methods market

Companies are focused on application of translational research principles on different populations for cancer treatment. On the other hand, EMT biomarkers segment is expected to witness the highest CAGR in the estimate period on account of wide usage of epithelial mesenchymal transition biomarkers in deciphering complex processes leading to cancer metastasis in effective development of oncology therapeutics.

Regional Insights

North America was the largest regional market in 2018 and will continue its dominance in future owing to a number of research projects carried out in the region coupled with government funding to various institutes for research. Moreover, presence of target population and rising investments in R&D by key market entities will drive the market further.

Asia Pacific CTC detection sector is projected to grow at a rapid pace due to increasing interest of international companies to expand their respective business in economies like India and China. In addition, presence of numerous untapped opportunities in such emerging economies is anticipated to increase the market share of this region over the coming years.

Circulating Tumor Cells (CTC) Market Share Insights

Key market participants focus on collaborations with various hospitals that are involved in provision of preventive medicine for personalized therapy for oncology diseases and universities for cancer studies. For instance, Epic Sciences announced collaboration with the Abramson Cancer Center of the University of Pennsylvania (Penn) to improve multiple studies for exploring biomarkers, which are identified by CTC analysis.

In 2014, Advanced Cell Diagnostics established a new subsidiary in Europe. This subsidiary has sales, marketing, and technical support staff in Germany and U.K. while its warehousing and distribution center located close to Milan and Italy

Some of the prominent companies are Clearbridge BioMedics; Fluxion Biosciences, Inc.; AdnaGen AG; Advanced Cell Diagnostics; Apocell; Cynvenio Biosystems; Aviva Biosciences; Biocep Ltd.; Biocept, Inc.; Biofluidica; Canopus Biosciences; Creatv Microtech, Inc.; Epic Biosciences; Vitatex, Inc.; Greiner Bio-one GmbH; Ikonisys, Inc.; Sysmex Corp.; Janssen Diagnostics; CellTraffix, Inc.; and Miltenyi Biotech.

Report Scope



Base year for estimation


Actual estimates/Historical data

2014 - 2017

Forecast period

2019 - 2025

Market representation

Revenue in USD Million and CAGR from 2019 to 2025

Regional scope

North America, Europe, Asia Pacific, Latin America, and MEA

Country scope

U.S., Canada, U.K., Germany, Spain, France, Italy, Russia, China, Japan, India, South Korea, Singapore, Australia, Brazil, Argentina, South Africa, and UAE

Report coverage

Revenue forecast, competitive landscape, growth factors and trends

15% free customization scope (equivalent to 5 analyst working days)

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Segments Covered in the Report

This report forecasts revenue and volume growth at global, regional, and country levels and provides an analysis of the latest industry trends in each of the sub-segments from 2014 to 2025. For the purpose of this study, Grand View Research has segmented the global Circulating Tumor Cells (CTC) market report on the basis of technology, application, and region:

  • Technology Outlook (Revenue, USD Million, 2014 - 2025)

    • CTC Enrichment Methods

      • Ex vivo Positive Selection

      • In vivo Positive Selection

      • Negative Selection

      • Microchips

      • Single Spiral Microchannel

    • CTC Detection Methods

      • Immunocytochemical Technologies

      • Molecular (RNA)-based Technologies

      • Functional in vitro Cell Invasion Assay

      • Xenotransplantation Models

    • CTC Analysis

  • Application Outlook (Revenue, USD Million, 2014 - 2025)

    • Cancer Stem Cell Research

    • EMT Biomarkers Development

    • Tumorgenesis Research

    • Other Applications

  • Regional Outlook (Revenue, USD Million, 2014 - 2025)

    • North America

      • U.S.

      • Canada

    • Europe

      • U.K.

      • Germany

      • Spain

      • France

      • Italy

      • Russia

    • Asia Pacific

      • China

      • Japan

      • India

      • South Korea

      • Singapore

      • Australia

    • Latin America

      • Brazil

      • Argentina

    • MEA

      • South Africa

      • UAE

Key questions answered by the report
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