GVR Report cover Dental Bone Graft And Substitutes Market Size, Share & Trends Report

Dental Bone Graft And Substitutes Market Size, Share & Trends Analysis Report By End-use (Dental Clinics, Hospitals), By Material Type (Xenograft, Synthetic), By Application, By Region, And Segment Forecasts, 2021 - 2028

  • Published Date: Jan 2021
  • Report ID: GVR-4-68038-153-5
  • Number of Pages: 100
  • Format: Electronic (PDF)
  • Historical Data: 2016 - 2019

Report Overview

The global dental bone graft and substitutes market size was valued at USD 663.2 million in 2020 and is expected to grow at a compound annual growth rate (CAGR) of 11.4% from 2021 to 2028. Increasing usage of bone grafts in dental implant surgeries is propelling the market growth. Dental implant surgery has become very popular with advanced surgical techniques, such as bone grafts and bone regeneration. Moreover, the increasing success rate of these surgeries is fueling market growth. According to the American Dental Association report, around 95 to 98% success rate has been reported for implant surgeries in 2017. Around 5 million implant procedures are performed in the U.S. every year. Bone grafting before implant placement helps maintain the existing jaw and increases the chances of successful implant surgery. This is also fueling product demand.

The U.S. dental bone graft & substitutes market size, by material type, 2016 - 2028 (USD Million)

Increasing use of biocompatible and synthetic dental grafts is another factor propelling the market growth. TCP is mostly used as a synthetic scaffold in dentistry. It provides higher osteoconductivity as compared to allografts. Initiatives by the industry players, such as new product launches and M&As, are also contributing to revenue growth. For instance, in May 2018, Dentsply Sirona collaborated with Datum Dental, Ltd. for the distribution of the OSSIX brand, which is indicated for bone and tissue regeneration. In January 2017, Antibe Therapeutics Inc. launched PentOS OI Max for dental and maxillofacial surgery.

The growing dental tourism sector in developing countries is propelling the market. Asia Pacific region, especially China and India, is one of the major contributors to this growth. The low cost of dental treatments and the availability of expert surgeons will lead to an increase in the number of foreign patient visits for these procedures. The cost for socket preservation, ridge augmentation is nearly 1/4th as compared to the U.S. and Europe. The aforementioned factors are expected to propel the overall market growth in the coming years.

The rising target population plays a significant role in the growth of the market. According to the Department of Economic and Social Affairs Population Division, the global geriatric population has grown from 9.2% in 1990 to 11.7% in 2013 and is expected to grow to 21.1% by 2050. Thus, with the rising prevalence of periodontal diseases, root caries and edentulous, and the growing geriatric population, the demand for dental grafting is increasing.

Material Type Insights

The xenograft material type segment held the largest revenue share of over 47% in 2020. A xenograft is a bone taken from an animal source, such as bovine. The most commonly used xenograft is Bio-Oss. Key industry players are taking the initiative to launch new xenograft products for better penetration. For instance, in 2019 Marks Biotech Inc. launched Novobone to its product portfolio.

The synthetic material segment is expected to exhibit the fastest CAGR over the forecast period. The growth can be attributed to higher osteoconductivity, hardness, and better acceptance of synthetic materials, such as ceramic, polymer-based, and BMPs. Moreover, synthetic materials have a lower risk of disease transmission than xenograft and allograft, which is boosting segment growth.

Increasing use of synthetic grafts with HAP, TCP, which has shown better biocompatibility as compared to others is also fueling the segment growth. The industry players are continuously trying to develop new products with better biocompatibility, bioactivity, and suitable mechanical properties. For instance, in June 2019, Biogennix received 510(K) clearance from the U.S. FDA for Agilon, which is fully biocompatible with human bone.

Application Insights

Socket preservation held the largest revenue share of 29% in 2020. It is a method that is used to decrease bone loss after tooth extraction from the tooth socket in the alveolar bone. A rising number of dental implant surgeries and increasing awareness about oral health care are driving the growth of this segment.

Ridge augmentation is estimated to be the fastest-growing application segment from 2021 to 2028 owing to quick recovery time and painless procedure. Moreover, alveolar volume gain is also possible with the help of ridge augmentation, thus boosting the segment growth. Some of the most common grafting materials used arePuros by Zimmer Biomet, Bio-Oss by Osteohealth, and INFUSE bone graft by Medtronic.

End-use Insights

Dental clinics held the largest revenue share of over 75% in 2020. With the growing dental graft surgeries performed annually, clinics are gaining popularity due to the convenience offered and easy availability of expert surgeons. Moreover, compared to hospitals, these clinics are specialized to deliver safer and quicker same-day procedures.

Global dental bone graft & substitutesmarket share, by end-use, 2020 (%)

The hospitals segment is anticipated to witness the maximum growth rate over the forecast period owing to the availability of a wide range of reconstructive procedures under these facilities. Few hospitals, which are self-funded and are associated with tissue banks, are aiming to provide class-leading services. Moreover, hospitals collaborate with various insurance companies for better and fast reimbursement. Owing to all these benefits, the overall footfall in hospitals is more as compared to clinics.

Regional Insights

Europe accounted for the largest revenue share of more than 39% in 2020 owing to the high number of dental implant surgeries performed and the target population in the region. However, North America is projected to lead the global market over the coming years. Asia Pacific is expected to register the fastest CAGR from 2021 to 2028 owing to increased medical tourism and supportive government initiatives.

Moreover, increasing cases of dental problems due to the rising geriatric population will also support regional market growth. On the contrary, stringent regulatory guidelines in some of the countries can limit the market growth. For example, in South Korea, the product should be approved by the Korean Food and Drug Administration (KFDA) before marketing. In Australia, the graft products are regulated by the Therapeutic Goods Administration (TGA). Thus, a stringent regulatory scenario in these countries creates a barrier for foreign companies to enter the regional market.

The availability of resources that enable the development of advanced technology at a cheaper cost is resulting in an increased number of manufacturing facilities in the region, particularly in China and India. China has released Order 650 (former Order 276), Regulations for the Supervision and Administration of Medical Devices, to restrict foreign investment in the country, mainly to protect the domestic medical devices manufacturing industry. As a result, the number of local bone graft manufacturers is anticipated to grow in near future.

Key Companies & Market Share Insights

The industry is marked by the presence of various small- and large-scale industry players. The market is highly fragmented and competitive. Companies are constantly involved in strategic initiatives, such as acquisitions, new product launches, technological advancements, and collaborations, to gain deeper penetration. For instance, in January 2019, Straumann Group partnered with Tianjin ZhengLi Technology Company Ltd. to enter the China market. In March 2019, BioHorizons acquired Intra-Lock to include the IntraSpin system in its portfolio for better penetration. Some of the key players in the global dental bone graft and substitutes market include:

  • Institut Straumann AG

  • Dentsply Sirona

  • Medtronic PLC

  • Zimmer Biomet

  • RTI Surgical, Inc.

  • Geistlich Pharma AG

  • BioHorizons

  • Orthogen

  • Dentium Co., Ltd.

  • LifeNet Health

Dental Bone Graft And Substitutes Market Report Scope

Report Attribute


Market size value in 2021

USD 719.1 million

Revenue forecast in 2028

USD 1371.6 million

Growth Rate

CAGR of 11.4%

Base year for estimation


Historical data

2016 - 2019

Forecast period

2021 - 2028

Quantitative units

Revenue in USD million and CAGR from 2021 to 2028

Report coverage

Revenue forecast, company ranking, competitive landscape, growth factors, and trends

Segments covered

Material type, application, end-use, region

Regional scope

North America; Europe; Asia Pacific; Latin America; MEA

Country scope

U.S.; Canada; U.K.; Germany; France; Italy; Spain; China; India; Australia; South Korea; Brazil; Mexico; South Africa

Key companies profiled

Institut Straumann AG; Dentsply Sirona; Medtronic PLC; Zimmer Biomet; RTI Surgical, Inc.; Geistlich Pharma AG; BioHorizons; Orthogen; Dentium Co., Ltd.; LifeNet Health

Customization scope

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Segments Covered in the Report

This report forecasts revenue growth at global, regional, and country levels and provides an analysis of the latest industry trends in each of the sub-segments from 2016 to 2028. For the purpose of this study, Grand View Research has segmented the global dental bone grafts and substitutes market report on the basis of material type, application, end-use, and region:

  • Material Type Outlook (Revenue, USD Million, 2016 - 2028)

    • Allograft

      • Demineralized Bone Matrix

      • Others

    • Autograft

    • Xenograft

    • Synthetic

  • Application Outlook (Revenue, USD Million, 2016 - 2028)

    • Ridge Augmentation

    • Sinus Lift

    • Periodontal Defect Regeneration

    • Implant Bone Regeneration

    • Socket Preservation

  • End-use Outlook (Revenue, USD Million, 2016 - 2028)

    • Hospitals

    • Dental Clinics

  • Regional Outlook (Revenue, USD Million, 2016 - 2028)

    • North America

      • U.S.

      • Canada

    • Europe

      • U.K.

      • Germany

      • France

      • Italy

      • Spain

    • Asia Pacific

      • China

      • India

      • Australia

      • South Korea

    • Latin America

      • Brazil

      • Mexico

    • Middle East & Africa

      • South Africa

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