GVR Report cover Dental Bone Grafts And Substitutes Market Size, Share & Trend Report

Dental Bone Grafts And Substitutes Market Size, Share & Trend Analysis Report By Material Type (Allograft, Xenograft, Synthetic), By Application, By End Use, By Region, And Segment Forecasts, 2022 - 2030

  • Report ID: GVR-4-68038-153-5
  • Number of Pages: 100
  • Format: Electronic (PDF)
  • Historical Range: 2018 - 2020
  • Industry: Healthcare

Report Overview

The global dental bone grafts and substitutes market size was estimated at USD 645.2 million in 2021 and is expected to witness a CAGR of 9.4% during the forecast period. The increasing use of bone grafts and a growing number of dental implant surgeries are propelling the revenue. The advent of the COVID-19 resulted in significant revenue losses, especially in the first and second quarters of 2021. This was due to the halting of dental practices around the globe in the light of surging COVID-19 cases and the risk of disease transmission. However, the market is recovering from the impact of COVID-19  as dental treatments have been resumed drastically as the measures to curb the virus have been successful.  

U.S. dental bone grafts and substitutes market size, by material type, 2020-2030 (USD Million)

The U.S Allograft Product Segment is expected to witness a high compound annual growth of 10.5% during the forecast period. Furthermore, Dental implant surgery has now become very popular with advanced surgical techniques such as bone grafts and bone regeneration. Moreover, increasing success rates of these surgeries are fueling the market. According to the American Dental Association report, around 95% to 98% success rate has been reported for implant surgeries as of 2019. Around 5 million implant procedures are performed in the U.S. every year. Bone grafting prior to implant placement helps to maintain the existing jaw and increases the chances of successful implant surgery, thus fueling the revenue.

The use of biocompatible and synthetic dental grafts is another growth propelling factor for the market. TCp is mostly used as a synthetic scaffold in dentistry. It provides higher osteoconductivity as compared to allografts. The increasing initiatives by the industry players such as new product launch, merger & acquisition is also affecting the revenue. For instance, In May 2018, Dentsply Sirona collaborated with Datum Dental, Ltd. for the distribution of the OSSIX brand which is indicated for bone and tissue regeneration. In January 2017, Antibe Therapeutics Inc. launched PentOS OI Max for dental and maxillofacial surgery. The aforementioned factors are expected to boost revenue in the coming years.

Growing dental tourism in developing countries is propelling the market. Asia Pacific region especially China, and India is one of the major contributors to this growth. The low cost of dental treatment and availability of surgeons will lead to an increase in the number of foreign patient visits for these procedures. The cost for socket preservation and ridge augmentation is nearly 1/4th as compared to the U.S. and Europe. The aforementioned factors are expected to propel the revenue in the coming years.

The rising target population plays a significant role in the growth of the dental bone grafts & substitutes market. According to the Department of Economic and Social Affairs Population Division, the global share of people 60 years and above has grown from 9.2% in 1990 to 11.7% in 2013, and this share is expected to rise to 21.1% by 2050. With an elevated prevalence of periodontal disease, root caries, and edentulous along with the geriatric population the demand for dental grafting is increasing.

The onset of the pandemic strained the dental industry as measures were taken by the state governments globally to curb the transmission of the virus and as dental treatments are high contact services, the majority of the dental practices were halted. Companies like Dentsply Sirona and Institut Straumann AG reported operational and supply chain constraints as a result of the pandemic which directly affected their revenues. However, the dental practices resumed by the end of 2020 under strict COVID-19 protocols and guidelines, after the introduction of an effective vaccine. Dentsply Sirona stated that its end-use and equipment segment which comprises dental bone graft materials reported a 28.7% growth in 2021.

Material Type Insights

Xenograft product segment held the largest revenue share of 21.2% in 2021. Based on product, the market is segmented into xenograft, allograft, and synthetic material. A xenograft is a bone taken from an animal source such as a bovine and implanted into the human body. The most commonly used xenograft is Bio-Oss. Key industry players are taking the initiative to launch new xenograft products for better penetration. For instance, in 2019 Marks Biotech Inc. launched Novobone, a xenograft in order to improve its bone grafting product portfolio. The other key players include ACE Surgical, BioHorizons, etc.

The synthetic segment is expected to exhibit lucrative growth over the forecast period. The growth can be attributed to its higher osteoconductivity, hardness, and better acceptance. There are various types of synthetic materials available in the market such as ceramic, polymer-based, BMPs, etc. The chance of disease transmission is low with synthetic grafting as compared to xenograft & allograft, which is further boosting the growth. Moreover, increasing demand to develop biocompatible grafts to reduce adverse reactions is driving this segment.

Increasing uses of synthetic grafts with HAP, TCP which has shown better biocompatibility as compared to others is fueling the growth. The polymer-based grafts also have shown good biocompatibility. The industry players are continuously trying to develop new products with better biocompatibility, bioactivity, and suitable mechanical properties. For instance, in June 2019, Biogennix received 510(K) clearance from USFDA for Agilon, which is fully biocompatible with human bone. The aforementioned factors are boosting revenue.

Application Insights

The socket preservation application segment held the largest revenue share of 28.8% as of 2021. The application segment includes Ridge Augmentation, Sinus Lift, Periodontal Defect Regeneration, Implant Bone Regeneration, and Socket PreservationIt is a method that is used to decrease bone loss after tooth extraction from tooth socket in the alveolar bone. An escalating number of dental implant surgeries and increasing awareness among people about oral health care are the driving factors for the growth of this segment.

Ridge augmentation also held a significant revenue share owing to its quick recovery time and painless procedure. The demand for this procedure is increasing in order to achieve long-term survival and successful implant placement. Moreover, alveolar volume gain is also possible with the help of ridge augmentation, thus boosting the growth. Some of the most common grafting materials used arePuros by Zimmer Biomet, Bio-Oss by Osteohealth, INFUSE bone graft by Medtronic, etc.  

End-use Insights

The dental clinics end-use segment held the largest revenue share of 75.3% as of 2021. With growing dental graft surgeries performed annually, clinics are gaining popularity due to its convenience, and easy availability of surgeons. Compared to hospitals, these clinics are specialized to deliver safer and quicker same-day procedures. Moreover, growing awareness regarding oral health is further propelling the market.

Global dental bone grafts and substitutesmarket share, by end use, 2021 (%)

Private dental clinics or specialty clinics are present in large numbers and typically have skilled practitioners specializing in bone grafting procedures. Manufacturing companies have a wide delivery network and target dental clinics primarily through direct sales; multiple smaller clinics tend to collectively bring in more customers than a single hospital. For instance, the Institute Straumann stated in its annual report that its professionals primarily operated in 1,300 dental clinics, as of 2020, and place 300,000 implants annually.

The hospital segment is anticipated to witness lucrative growth during the forecast period. The growth can be attributed to the availability of a wide range of reconstructive procedures under these facilities. Few hospitals are self-funded and are associated with tissue banks aiming to provide class-leading services. Moreover, hospitals collaborate with various insurance companies for better and fast reimbursement. Owing to all these benefits the overall footfall in hospitals is more as compared to clinics.

Regional Insights

North America dominated the global dental bone grafts & substitutes market in terms of revenue share in 2021. The increasing target population and the increasing number of dental implant surgeries in this region are driving the growth. Europe held the second-largest share and is expected to show significant growth in the coming years. The Asia Pacific region is expected to show lucrative growth during the forecast period. The growth can be attributed to an increased number of medical tourism and government initiatives.

Moreover, a growing aging population in the Asia Pacific region is further increasing the risk of dental problems. On the contrary, stringent regulatory guidelines in some countries can limit growth in the near future. In South Korea, the product should be approved by the Korean Food and Drug Administration (KFDA) before marketing. In the case of Australia, the graft products are regulated by Therapeutic Goods Administration (TGA). The stringent regulatory scenario in these countries creates a barrier for foreign players to enter the market.

Medical tourism in India & China for dental grafting surgeries is another growth propelling factor for the market. In addition, the availability of resources that enable the development of advanced end-use at a cheaper cost is resulting in an increased number of manufacturing facilities in these countries. China has released Order 650 (former Order 276), Regulations for the Supervision and Administration of Medical Devices, to restrict foreign investment in the country, mainly to protect the domestic medical devices manufacturing industry. As a result, the number of local bone graft manufacturers is anticipated to grow in near future.

Key Companies & Market Share Insights

The players are constantly involved in strategic initiatives such as acquisitions, new product launches, technological advancements, and collaborations in order to gain deeper penetration. For instance, In March 2021, Institut Straumann signed an investment agreement with the Shanghai Xin Zhuang Industrial Park to establish its first Campus in China which will comprise a manufacturing plant, education, and innovation center in the country. the China Campus will provide various educational programs as well as products from the Straumann Group’s implant and orthodontics portfolio for China, catering to the rapidly growing demands of Chinese dentists and patients for dental solutions. In March 2019, BioHorizons acquired Intra-Lock to include the IntraSpin system in its portfolio for better penetration. Some of the key industry players in the global dental bone grafts and substitute market include:

  • Dentsply Sirona

  • Biohorizons Inc.

  • Zimmer Biomet

  • Dentsply Sirona

  • Rti Surgicals

  • Medtronic

  • Geistlich Pharma Ag

  • Dentium Co, Ltd.

  • Orthogen.

  • Lifenet Health

Dental Bone Grafts And Substitutes Market Report Scope

Report Attribute


Market size value in 2022

USD 0.69 billion

Revenue forecast in 2030

USD 1.42 billion

Growth rate

CAGR of 9.4% from 2021 to 2030

Base year for estimation


Historical data

2018 - 2020

Forecast period

2021 - 2030

Market representation

Revenue in USD million & CAGR from 2020 to 2028

Regional coverage

Revenue forecast, company share, competitive landscape, growth factors, and trends

Segments covered

Material type, product type, application, end-use, region

Report scope

North America; Europe; Asia Pacific; Latin America; MEA

Country Scope

U.S.; Canada; Germany; UK; France; Italy; Spain; China; Japan; India; South Korea; Australia; Brazil; Mexico; Argentina; Colombia; South Africa; Saudi Arabia; UAE

Key companies profiled

Geistlich Pharma AG; Medtronic; Zimmer Holding Inc; RTI Surgical, Inc.; Dentsply Sirona etc; Biohorizons Iph, Inc. (US); Orthogen, LLC (US)

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Segments Covered in the Report

This report forecasts revenue growth at global, regional & country levels and provides an analysis of the industry trends in each of the sub-segments from 2018 to 2030. For this study, Grand View Research has segmented the global dental bone grafts & substitutes market report on the basis of material type, application, end-use, product type and region:

  • Material Type Outlook (Revenue, USD Million, 2018 - 2030)

    • Allograft

      • Demineralized Bone Matrix

      • Others

    • Xenograft

    • Synthetic

    • Autograft

  • Product Type Outlook (Revenue, USD Million, 2018 - 2030)

    • Bio OSS

    • Osteograf

    • Grafton

  • Application Outlook (Revenue, USD Million, 2018 - 2030)

    • Ridge Augmentation

    • Sinus Lift

    • Periodontal Defect Regeneration

    • Implant Bone Regeneration

    • Socket Preservation

  • End-use Outlook (Revenue, USD Million, 2018 - 2030)

    • Hospitals

    • Dental clinics

  • Regional Outlook (Revenue, USD Million, 2018 - 2030)

    • North America

      • U.S.

      • Canada

    • Europe

      • UK

      • Germany

      • France

      • Italy

      • Spain

    • Asia Pacific

      • China

      • India

      • Australia

      • South Korea

    • Latin America

      • Brazil

      • Mexico

    • Middle East & Africa

      • South Africa

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