GVR Report cover Dental Regeneration Market Size, Share & Trends Report

Dental Regeneration Market Size, Share & Trends Analysis Report By Type (Hard Tissue, Soft Tissue), By Age Group (Pediatric, Adult, Geriatric), By End-User (Hospitals, Dental Clinics), By Region, And Segment Forecasts, 2023 - 2030

  • Report ID: GVR-4-68040-042-4
  • Number of Pages: 100
  • Format: Electronic (PDF)
  • Historical Range: 2018 - 2021
  • Industry: Healthcare

Report Overview

The global dental regeneration market size was valued at USD 4.9 billion in 2022 and is expected to expand at a compound annual growth rate (CAGR) of 6.1% from 2023 to 2030. The growing geriatric population and increasing dental diseases such as periodontal diseases, dental caries, and hereditary dentine disorders are the key factors driving the growth of the market. Also, advancements in regenerative therapies, increased investment by government institutions & rising healthcare infrastructure are contributing to the growth of the market.

U.S. dental regeneration market size, by type, 2020 - 2030 (USD Billion)

Oral diseases are largely preventable and pose a major health risk for many countries and affect individuals throughout their life, causing pain, disfigurement, discomfort, and even death. According to WHO estimation, around 3.5 billion people are affected by oral diseases. Untreated dental caries is the most prevalent disorder & most common health condition, according to the Global Burden of Disease 2019. Also, it is estimated that the prevalence of complete tooth loss is around 7% in adults aged 20- 60 years and 23% for people aged 60 years or older. Thus, these dental problems & disorders would propel the growth of the dental regeneration industry in the coming years.

However, the covid-19 pandemic resulted in a negative impact on the global dental regeneration industry. The lockdown imposed due to the COVID-19 pandemic predisposed people to altered behavioral profiles and unhealthy lifestyles. Due to this, several studies have linked these factors to dental caries and obesity among children. However, unlike obesity, caries is often slowly progressive and sub-clinical, making early diagnosis challenging. Also, the rate of performing surgeries declined during the pandemic.

Vital pulp therapy is one form of regenerative medicine that dentists have been utilizing for a long time. The use of various regeneration techniques by clinicians has increased recently.  For instance, bone grafting and guided tissue regeneration (GTR) therapies, which use well-validated methods using biocompatible scaffolds to enhance tissue regeneration, were utilized for many years by oral surgeons, periodontists, and implantologists. Moreover, regenerative endodontic therapies, are increasingly been adopted by endodontists and pediatric dentists around the world. 

Regenerative dentistry has introduced an entirely novel method for the replacement of damaged dental tissues. The degeneration of the pulp vitality, which may be caused by chemical injury, trauma, or dental caries, is one of the most significant worldwide health problems. To regenerate the pulp-dentin complex in its entirety, in 2021, two regenerative therapies (cell transplantation and cell homing therapies) were developed. Despite this, the adoption of cell-based therapies still faces several difficulties, primarily financial issues. As a result, efforts to target cell homing for pulp-dentin complex regeneration are developed as an easier, safer, and more economical alternative to cell-based transplantation therapy.

Type Insights

The hard tissue segment dominated the market for dental regeneration and accounted for the largest revenue share of 59.2% in 2022. Based on hard tissue, the segment is further divided into dentin, cementum, and enamel. Enamel accounted for the largest share of 60.5% in 2022. The increasing prevalence of enamel hypoplasia, dental caries, and periodontitis is a key factor driving the demand for enamel regenerative procedures For instance, according to WHO estimation, there are more than 1 billion cases of severe periodontal disease globally affects approximately 19% of the adult population. Tobacco use and poor dental hygiene are the main risk factors for periodontal disease.

Soft tissue is anticipated to register the fastest CAGR growth during the forecast period. Based on soft tissue, the segment is further divided into pulp and gum. The gum segment is accounted for the largest share of 65.9% and is also anticipated to register the fastest CAGR growth during the forecast period. Periodontal diseases are mainly the result of inflammation and infections of the bone and gums that surround and support the teeth. The gums can swell, turn red, and bleed in gingivitis's early stages. For instance, according to a CDC report, 47.2% of adults aged 30 and older have periodontal disease in the U.S. Age is a factor in periodontal disease, which affects 70.1% of adults 65 and older.

Age Group Insights

Based on the age group, the geriatric age group dominated the market for dental regeneration and accounted for the largest revenue share of 37.3% in 2022. Tooth loss in the elderly population, which decreases nutrient intake and is likely to contribute to systemic health issues, is the key driver of the market. For instance, according to the CDC report for 2021, about one-fifth of people 65 and older have lost all of their teeth. Complete tooth loss occurred twice as common in adults 75 and older (26%) than in those 65 to 74 (13%). It is estimated that 98 million people in the U.S., or 24% of the population, are expected to be 65 or older by 2060.

The adult is anticipated to register the fastest CAGR growth during the forecast period. The growing prevalence of periodontal diseases & dental caries, and the rising adult population are the key factors contributing to the growth of the market. According to the World Bank, in 2021, the adult population was 65% of the total population. Also, according to the WHO, periodontal diseases are anticipated to affect around 19% of the adult population, representing more than 1.0 billion cases around the globe.

End-User Insights

The dental clinic’s segment dominated the market for the dental regeneration industry and accounted for the largest market share of 56.4% in 2022. The majority of people visit privately owned dental clinics as they are more affordable, offer access to specialists, and deploy advanced equipment. There are more independent practices around the globe. For instance, according to the center for disease control & prevention (CDC), 65.5% of adults aged between 18-64 had a dental visit in 2019, and 86.9% of children visited dental clinics in the same year.

Global dental regeneration market share, by end-user, 2022 (%)

The hospital segment is anticipated to register the fastest CAGR at 6.4% during the forecast period. The adoption of advanced regenerative therapies is higher in hospitals as compared to other dental practices. In addition, hospitals have strong tie-ups with manufacturing firms which is contributing to the growth of the dental regeneration industry.

Regional Insights

North America dominated the dental regeneration industry and accounted for the largest revenue share of 39.8% in 2022. This can be attributed to the increasing incidence of tooth loss, and the rising prevalence of diseases such as periodontal, dental caries, pupal periapical diseases, and enamel hypoplasia. These are the key factors driving the growth of the market in the region. Furthermore, advancements in dental regenerative procedures and the growing geriatric population are also contributing to the market growth. For instance, according to a report published by the International Journal of Medical Research & Health Sciences, the prevalence of adult subjects with dentine hypersensitivity was 12.3% in the U.S. in 2019.

Dental Regeneration Market Trends, by Region, 2023 - 2030

Asia Pacific is anticipated to register the fastest growth at 6.7% CAGR during the forecast period The key factors driving the market in the region include an increasingly aging population, growing prevalence of dental diseases such as dentin hypersensitivity, dental caries & periodontal diseases, and rise in disposable incomes. For instance, according to a report published by NIH, the prevalence of dental caries is 54.1% in 2021 in India. It is reported that 62% of patients are above 18 years and 52% among 3-18 years of age. Also, 29% of cases of early childhood caries were diagnosed using missing, decaying, and filled teeth as diagnostic criteria.

Key Companies & Market Share Insights

Key market players are undertaking various strategic initiatives such as partnership agreements, collaborations, mergers & acquisitions, and geographic expansion, aiming to strengthen their services, to gain a competitive advantage. For instance, in July 2022, My dentist collaborated with a dental clinic to strengthen their leadership in the medical industry and to provide a quality experience to their patients Some prominent players in the global dental regeneration market include:

  • Smile Dental Care

  • Apollo White Dental

  • Integrated Dental Holdings

  • My Dentist

  • Floss Dental Clinic

  • Axiss Dental

  • Aspen Dental Clinic

  • Heartland Dental

  • Delta Dental

  • Clove Dental

Dental Regeneration Market Report Scope

Report Attribute


Market size value in 2023

USD 5.2 billion

Revenue forecast in 2030

USD 7.8 billion

Growth rate

CAGR of 6.1% from 2023 to 2030

Base year for estimation


Actual estimates/Historical data

2018 - 2021

Forecast period

2023 - 2030

Quantitative units

Revenue in USD million/billion, CAGR from 2023 to 2030

Report coverage

Revenue forecast, company share, competitive landscape, growth factors, trends

Segments Covered

Type, age group, end-user, region

Regional scope

North America; Europe; Asia Pacific; Latin America; Middle East & Africa

Country scope

U.S.; Canada; U.K.; Germany; France; Italy; Spain; Denmark; Sweden; Norway; China; India; Japan; Australia; Thailand; South Korea; Brazil; Mexico; Argentina; South Africa, Saudi Arabia; UAE; Kuwait

Key companies profiled

Smile Dental Care; Apollo White Dental; Integrated Dental Holdings; My Dentist; Floss Dental Clinic; Axiss Dental; Aspen Dental Clinic; Heartland Dental; Delta Dental; Clove Dental

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Global Dental Regeneration Market Report Segmentation

This report forecasts revenue growth at global, regional & country levels and provides an analysis of the latest industry trends in each of the sub-segments from 2018 to 2030. For the purpose of this study, Grand View Research has segmented the global dental regeneration market report based on type, age group, end-user, and region.

Global Dental Regeneration Market Report Segmentation

  • Type Outlook (Revenue, USD Million, 2018 - 2030)

    • Hard Tissue

      • Dentin

      • Cementum

      • Enamel

    • Soft Tissue

      • Gum

      • Pulp

  • Age Group Outlook (Revenue, USD Million, 2018 - 2030)

    • Pediatric

    • Adult

    • Geriatric

  • End-User Outlook (Revenue, USD Million, 2018 - 2030)

    • Hospitals

    • Dental Clinics

    • Others

  • Regional Outlook (Revenue, USD Million, 2018 - 2030)

    • North America

      • U.S.

      • Canada

    • Europe

      • U.K.

      • Germany

      • France

      • Italy

      • Spain

      • Denmark

      • Sweden

      • Norway

    • Asia Pacific

      • Japan

      • China

      • India

      • Australia

      • South Korea

      • Thailand

    • Latin America

      • Brazil

      • Mexico

      • Argentina

    • Middle East & Africa

      • South Africa

      • Saudi Arabia

      • UAE

      • Kuwait

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