DNA synthesizers are DNA sequencers used to examine the sequence of nucleotides in a DNA sample. DNA synthesizers can create specific DNA molecules to treat various diseases by replacing a damaged or faulty section of DNA with a repaired unit. Synthetic DNA is in growing demand across numerous sectors of commercial and research activities. Engineering biology, nanotechnology, therapy, and data storage are set for rapid development as DNA is delivered at scale and low cost. Stimulated by successes in gene editing technologies and NGS, DNA synthesis at present is an expanding industry.
Technological advancement is the major factor driving the market's growth—advances in synthesizing DNA many open opportunities for new research. For instance, Kilobaser RNA and DNA Synthesizer are developed to provide researchers across the globe with independent and unlimited access to vital life science tools. The chip and cartridge technology permits even untrained staff to quickly complete a successful RNA or DNA synthesis.
Furthermore, the DNA synthesis industry is growing rapidly, with a deceptive shift towards greener solutions to decrease the dependence on chemical reagents and organic solvents with possible adverse environmental effects to alleviate their costly discarding routes. For instance, new industry strategic partnerships have been formed to announce state-of-the-art technologies in the enzymatic DNA synthesis space. This can be demonstrated by joint ventures between Molecular Assemblies and Codexis and between Danaher and Integrated DNA Technologies, which intends to improve the enzymatic DNA synthesis facilities. Promising technologies comprise plasmid template methods, such as gene assembly, rolling circular amplification approaches, such as polymerase cycling assembly (PCA) or Gibson assembly, and template-independent enzymatic oligonucleotide synthesis (TiEOS), which exploits terminal deoxynucleotidyl transferase (TdT) as a DNA synthesis tool.
The market is segmented on product type, application, end-user, and region. The product type segment includes benchtop DNA synthesizers and automated DNA synthesizers. The application segment is further segmented into research and development, diagnostics, and therapeutics. The end-user segment is further segmented into biopharmaceutical companies, academic and research institutes, and contract research organizations.
Improvements in the sector have led to substantial scientific breakthroughs. For instance, in June 2021, DNA Script launched the SYNTAX platform with the SYNTAX System, the first benchtop nucleic acid printer powered by Enzymatic DNA Synthesis (EDS) technology. The SYNTAX System is an automated printer fully integrated for genomics workflows and molecular biology. In addition, in Sept 2022, Codex DNA, Inc. announced the commercial release and first shipment of the BioXp 9600 system, a next-generation high throughput platform developed to revolutionize synthetic biology workflows. The fully automated system allows researchers to overcome the process restrictions created by the cost, turnaround time, or complexity of alternate means of acquiring or building mRNA and DNA.
Segments |
Details |
Product Type |
Benchtop DNA Synthesizers Automated DNA Synthesizers |
Application |
Research And Development Diagnostics Therapeutics |
End-User |
Biotechnology companies Contract Research Organizations (CRO) Academic and research organizations |
Region |
North America (U.S., Canada), Europe (UK, Germany, France, Italy, Spain, Denmark, Sweden, Norway) Asia Pacific (Japan, China, India, Australia, Thailand, South Korea) Latin America (Brazil, Mexico, Argentina), Middle East & Africa (Saudi Africa, South Arabia, UAE, Kuwait) |
Major companies operating in the market include Danaher; Twist; Kilobaser; DNA Script; CsBio; K&A Laborgeraete; DNA Script; Biolytic.
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