Epigenetics Market Size, Share & Trends Report

Epigenetics Market Size, Share & Trends Analysis Report By Product (Reagents, Kits, Instruments), By Technology (DNA Methylation), By Application (Oncology), By End-use, By Region, And Segment Forecasts, 2024 - 2030

  • Report ID: 978-1-68038-583-0
  • Number of Pages: 120
  • Format: Electronic (PDF)
  • Historical Range: 2018 - 2023
  • Industry: Healthcare

Research Methodology

A three-pronged approach was followed for deducing the epigenetics market estimates and forecasts. The process has three steps: information procurement, analysis, and validation. The whole process is cyclical, and steps repeat until the estimates are validated. The three steps are explained in detail below:

Information procurement: Information procurement is one of the most extensive and important stages in our research process, and quality data is critical for accurate analysis. We followed a multi-channel data collection process for epigenetics market to gather the most reliable and current information possible.

  • We buy access to paid databases such as Hoover’s and Factiva for company financials, industry information, white papers, industry journals, SME journals, and more.
  • We tap into Grand View’s proprietary database of data points and insights from active and archived monitoring and reporting.
  • We conduct primary research with industry experts through questionnaires and one-on-one phone interviews.
  • We pull from reliable secondary sources such as white papers and government statistics, published by organizations like WHO, NGOs, World Bank, etc., Key Opinion Leaders (KoL) publications, company filings, investor documents, and more.
  • We purchase and review investor analyst reports, broker reports, academic commentary, government quotes, and wealth management publications for insightful third-party perspectives.

Analysis: We mine the data collected to establish baselines for forecasting, identify trends and opportunities, gain insight into consumer demographics and drivers, and so much more. We utilized different methods of epigenetics market data depending on the type of information we’re trying to uncover in our research.

  • Market Research Efforts: Bottom-up Approach for estimating and forecasting demand size and opportunity, top-down Approach for new product forecasting and penetration, and combined approach of both Bottom-up and Top-down for full coverage analysis.

  • Value-Chain-Based Sizing & Forecasting: Supply-side estimates for understanding potential revenue through competitive benchmarking, forecasting, and penetration modeling.

  • Demand-side estimates for identifying parent and ancillary markets, segment modeling, and heuristic forecasting.

  • Qualitative Functional Deployment (QFD) Modelling for market share assessment.

Market formulation and validation: We mine the data collected to establish baselines for forecasting, identify trends and opportunities, gain insight into consumer demographics and drivers, and so much more. We utilize different methods of data analysis depending on the type of information we’re trying to uncover in our research.

  • Market Formulation: This step involves the finalization of market numbers. This step on an internal level is designed to manage outputs from the Data Analysis step.

  • Data Normalization: The final market estimates and forecasts are then aligned and sent to industry experts, in-panel quality control managers for validation.

  • This step also entails the finalization of the report scope and data representation pattern.

  • Validation: The process entails multiple levels of validation. All these steps run in parallel, and the study is forwarded for publishing only if all three levels render validated results.

Epigenetics Market Categorization:

The epigenetics market was categorized into four segments, namely product (Reagents, Kits, Instruments, Enzymes, Services), application (DNA Methylation, Histone Methylation, Histone Acetylation, Large non - coding RNA, MicroRNA modification, Chromatin structures), technology (Oncology, Non - oncology), and regions (North America, Europe, Asia Pacific, Latin America, Middle East & Africa).

Segment Market Methodology:

The epigenetics market was segmented into product, application, technology, and regions. The demand at a segment level was deduced using a funnel method. Concepts like the TAM, SAM, SOM, etc., were put into practice to understand the demand. We at GVR deploy three methods to deduce market estimates and determine forecasts. These methods are explained below:

Market research approaches: Bottom-up

  • Demand estimation of each product across countries/regions summed up to from the total market.

  • Variable analysis for demand forecast.

  • Demand estimation via analyzing paid database, and company financials either via annual reports or paid database.

  • Primary interviews for data revalidation and insight collection.

Market research approaches: Top-down

  • Used extensively for new product forecasting or analyzing penetration levels.

  • Tool used invoice product flow and penetration models Use of regression multi-variant analysis for forecasting Involves extensive use of paid and public databases.

  • Primary interviews and vendor-based primary research for variable impact analysis.

Market research approaches: Combined

  • This is the most common method. We apply concepts from both the top-down and bottom-up approaches to arrive at a viable conclusion.

Regional Market Methodology:

The epigenetics market was analyzed at a regional level. The global was divided into North America, Europe, Asia Pacific, Latin America, and Middle East & Africa, keeping in focus variables like consumption patterns, export-import regulations, consumer expectations, etc. These regions were further divided into twenty-three countries, namely, the U.S.; Canada; Germany; the UK; France; Italy; Spain; Denmark; Sweden; Norway; China; Japan; India; Australia; Thailand; South Korea; Brazil; Mexico; Argentina; South Africa; Saudi Arabia; UAE; Kuwait.

All three above-mentioned market research methodologies were applied to arrive at regional-level conclusions. The regions were then summed up to form the global market.

Epigenetics market companies & financials:

The epigenetics market was analyzed via companies operating in the sector. Analyzing these companies and cross-referencing them to the demand equation helped us validate our assumptions and conclusions. Key market players analyzed include:

  • Roche Diagnostic, established toward the end of the 19th century, in the year 1896, now has an employee strength of 1,03,613 employees. It is headquartered in Switzerland. The company is involved in pharmaceuticals and diagnostics, committed to advancing science to improve people's lives. Focusing on personalized healthcare, Roche combines strengths in pharmaceuticals and diagnostics to tailor treatments for individual patients. As the world's largest biotech company, Roche excels in oncology, immunology, infectious diseases, and more. It leads in vitro diagnostics, cancer diagnostics, and diabetes management. Founded in 1896, Roche continually seeks innovative ways to prevent, diagnose, and treat diseases while promoting sustainability and improving patient access to medical advancements. Recognized for sustainability, Roche has been a Group Leader in the Dow Jones Sustainability Indices for 10 consecutive years.

  • Thermo Fisher Scientific, Inc., a company established in the year 1956, has an employee strength of 130,000 and its headquarters are in the United States. The company is one of the market leaders, that manufactures & provides laboratory reagents, equipment, analytical instruments, consumables, & diagnostic products. The company operates through numerous brands like Thermo Scientific, Applied Biosystems, Fisher Scientific, Invitrogen, and Unity Lab Services. It operates through four reportable segments: specialty diagnostics, life sciences solutions, analytical instruments, and laboratory products & services. The life sciences solutions segment includes four businesses: clinical Next-generation Sequencing (NGS), biosciences, bioproduction, and genetic sciences. The company provides services to pharmaceutical & biotechnology companies, clinical diagnostics laboratories, hospitals, government agencies, and research institutes.

  • Eisai Co. Ltd., founded in the year 1941, is headquartered in Japan. It is a U.S. pharmaceutical subsidiary of Eisai Co., Ltd. The company is focused on human health care, including oncology and neurology. Eisai strives to discover and develop innovative therapies, addressing unmet medical needs with a commitment to patient well-being. Operating globally, it integrates discovery, development, and marketing across its business groups, contributing to advancements in healthcare. This is a publicly held company, considered as one of the market innovators. Eisai has collaborated with the National Cancer Center to advance investigator-initiated clinical research for the anticancer agent tazemetostat. This collaboration is based on the “patient-proposed healthcare services” system. Eisai has launched an anticancer agent “Tazverik Tablets 200mg” (Tazemetostat Hydrobromide) in Japan to treat EZH2 gene mutation-positive follicular lymphoma.

  • Novartis is a pharmaceutical company specializing in developing and producing innovative drugs. Its key focus areas are oncology, rare diseases, neuroscience, immunology, respiratory, cardio-metabolic, and established medicines. With a global reach, Novartis distributes its products worldwide, and a significant portion of its revenue is generated in the United States. This company established in 1996 has an employee strength of 1,01,703. It has its headquarters in Switzerland. It is a publicly held company and is known as the market leader. It often opts for partnerships, collaborations, and acquisitions as a strategic approach to attain growth and expand its operations in newer areas and spaces.

  • Illumina, Inc., the company established in 1998 and headquartered in the United States, offers services and tools for applications in the life sciences domain, specifically for analyzing genetic material in clinical labs.        Activities such as sequencing, consumables, instruments, and services generate about 90% of the company’s revenue. Illumina's high-throughput technology facilitates whole genome sequencing in humans & other large organisms. In addition, the company provides lower throughput tools suitable for applications requiring smaller data outputs, such as cancer tumor screening and viral. The microarrays are also part of the company’s portfolio, which contributes to 10% of the total revenue. It is a publicly held company. In January 2021, Illumina completed New and Extended Oncology Collaborations with Kura Oncology, Myriad Genetics, Bristol-Myers Squibb, and Merck to Advance Comprehensive Genomic Profiling.

  • Promega Corporation, founded in 1978 and headquartered in the United States, is a producer of reagent toolkits and integrated systems that offer technical support to settings such as research, pharmaceutical, and diagnostic laboratories. In addition, the company also offers customised services in terms of manufacturing products, including automation & robotics equipment; Polymerase Chain Reaction (PCR) cloning technology; Ribonucleic Acid (RNA) & Deoxyribonucleic Acid (DNA) purification systems; and buffers, reagents, cloning, & restriction enzymes to customers. Promega provides kits and reagents to analyze DNA methylation, histone modification, and RNA transcription It is a privately held company and identified as an emerging market player in the Epigenetics Market.

  • Abcam plc., a biotechnology company, founded in 1998, and headquartered in the United Kingdom, is engaged in the business of development and provides antibodies for life science research and clinical communities. The company's product portfolio assists research on signaling and regulatory molecules, facilitating the study of proteins in biological pathways. Abcam's dedication to this research aims to contribute to developing treatments for various life-threatening diseases, including cancer and immune deficiency disorders. Abcam focuses on intensifying its product range, enhancing speed to market, and reaching underpenetrated consumer groups within its markets. In addition, the company selectively engages in partnerships and acquisitions to further its strategic objectives. It is a publicly held company and is considered an emerging player in the market.

  • Dovetail Genomics LLC, founded in 2013, in California is known for transforming whole life sciences scenarios by providing unprecedented access to genomic structure. The company captures the 3D architecture of the genome beside primary sequence information through standard NGS approaches by leveraging registered proximity ligation technologies, Researchers employ Dovetail Genomics' distinctive methods to deal with intricate challenges in chromatin topology analysis, small & large structural variant detection, haplotype phasing, de novo chromosome assembly, and microbiome analysis across various domains, such as developmental biology, epigenetics, cancer research, and evolutionary biology. With service and assay kit offerings, Dovetail Genomics collaborates with researchers, enhancing genome research.

  • Element Biosciences, Inc., the company formed in 2017, is into the development of genetic analysis tools aimed at research and diagnostic applications. It specializes in creating a modular and high-performance DNA sequencing platform to deliver quality data, ensure workflow flexibility, and enhance accessibility to NGS technology. This technology empowers medical researchers, offering them the means to benefit from improved research capabilities. It is a privately held company.

Value chain-based sizing & forecasting

Supply Side Estimates

  • Company revenue estimation via referring to annual reports, investor presentations, and Hoover’s.

  • Segment revenue determination via variable analysis and penetration modeling.

  • Competitive benchmarking to identify market leaders and their collective revenue shares.

  • Forecasting via analyzing commercialization rates, pipelines, market initiatives, distribution networks, etc.

Demand side estimates

  • Identifying parent markets and ancillary markets

  • Segment penetration analysis to obtain pertinent

  • revenue/volume

  • Heuristic forecasting with the help of subject matter experts

  • Forecasting via variable analysis

Epigenetics Market Report Objectives:

  • Understanding market dynamics (in terms of drivers, restraints, & opportunities) in the countries.

  • Understanding trends & variables in the individual countries & their impact on growth and using analytical tools to provide high-level insights into the market dynamics and the associated growth pattern.

  • Understanding market estimates and forecasts (with the base year as 2022, historic information from 2018 to 2021, and forecast from 2023 to 2030). Regional estimates & forecasts for each category are available and are summed up to form the global market estimates.

Epigenetics Market Report Assumptions:

  • The report provides market value for the base year 2022 and a yearly forecast till 2030 in terms of revenue/volume or both. The market for each of the segment outlooks has been provided on region & country basis for the above-mentioned forecast period.

  • The key industry dynamics, major technological trends, and application markets are evaluated to understand their impact on the demand for the forecast period. The growth rates were estimated using correlation, regression, and time-series analysis.

  • We have used the bottom-up approach for market sizing, analyzing key regional markets, dynamics, & trends for various products and end-users. The total market has been estimated by integrating the country markets.

  • All market estimates and forecasts have been validated through primary interviews with the key industry participants.

  • Inflation has not been accounted for to estimate and forecast the market.

  • Numbers may not add up due to rounding off.

  • Europe consists of EU-8, Central & Eastern Europe, along with the Commonwealth of Independent States (CIS).

  • Asia Pacific includes South Asia, East Asia, Southeast Asia, and Oceania (Australia & New Zealand).

  • Latin America includes Central American countries and the South American continent

  • Middle East includes Western Asia (as assigned by the UN Statistics Division) and the African continent.

Primary Research

GVR strives to procure the latest and unique information for reports directly from industry experts, which gives it a competitive edge. Quality is of utmost importance to us, therefore every year we focus on increasing our experts’ panel. Primary interviews are one of the critical steps in identifying recent market trends and scenarios. This process enables us to justify and validate our market estimates and forecasts to our clients. With more than 8,000 reports in our database, we have connected with some key opinion leaders across various domains, including healthcare, technology, consumer goods, and the chemical sector. Our process starts with identifying the right platform for a particular type of report, i.e., emails, LinkedIn, seminars, or telephonic conversation, as every report is unique and requires a differentiated approach.

We send out questionnaires to different experts from various regions/ countries, which is dependent on the following factors:

  • Report/Market scope: If the market study is global, we send questionnaires to industry experts across various regions, including North America, Europe, Asia Pacific, Latin America, and MEA.

  • Market Penetration: If the market is driven by technological advancements, population density, disease prevalence, or other factors, we identify experts and send out questionnaires based on region or country dominance.

The time to start receiving responses from industry experts varies based on how niche or well-penetrated the market is. Our reports include a detailed chapter on the KoL opinion section, which helps our clients understand the perspective of experts already in the market space.

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