GVR Report cover In Vitro Fertilization Market Size, Share & Trends Report

In Vitro Fertilization Market Size, Share & Trends Analysis Report By Type (Fresh Donor, Frozen Nondonor), By Instrument (Disposable Devices, Culture Media), By End-use, By Region, And Segment Forecasts, 2021 - 2028

  • Published Date: Jul, 2021
  • Base Year for Estimate: 2020
  • Report ID: 978-1-68038-823-7
  • Format: Electronic (PDF)
  • Historical Data: 2016 - 2019
  • Number of Pages: 120

Report Overview

The global in vitro fertilization market size was valued at USD 14.2 billion in 2020 and is expected to grow at a compound annual growth rate (CAGR) of 6.5% from 2021 to 2028. Key factors that are driving the market growth include rising reprotourism and the increasing cases of male and female infertility. Infertility is one of the major health concerns faced by individuals globally. According to the American Pregnancy Association, male infertility accounts for 30% of infertility cases and contributes to around one-fifth of infertility cases. The rising dependence on fertility treatments will support market growth. Availability of funds is leading to a rise in the adoption of in vitro fertilization (IVF) procedures.

U.S. in vitro fertilization market size, by instrument, 2018 - 2028 (USD Million)

In December 2016, the Ontario government announced a USD 50 million fertility program to cover IVF treatment for 5,000 people. Furthermore, the Singapore government offers around 75% co-funding for various ART procedures, such as IVF, Gamete Intrafallopian Transfer (GIFT), and Intracytoplasmic Sperm Injection (ICSI). In January 2015, the Centers for Disease Control and Prevention (CDC) reported that the use of ICSI has increased from 36.4% in 1996 to around 76.2% in 2012.

To increase the success rate of IVF, techniques, such as Testicular Sperm Extraction (PESA and TESE), are being introduced along with the development of new products. In June 2018, an Australian scientist developed an Artificial Intelligence (AI) tool called Ivy for the identification of an embryo with the best chance of pregnancy. Such technologies help increase the success rate of IVF pregnancies.


COVID-19 in vitro fertilization market impact: 22.4% decline from 2019 to 2020

Pandemic Impact

Post COVID Outlook

Mass closures of IVF centers and the termination of elective procedures in hospitals drove down IVF procedures globally

As the conditions are stabilizing, the market is expected to resume its original growth rate as clinics and hospitals are resuming with safety measures implemented and written consent from patients.

The IVF market declined to USD 14 billion from 2019 to 2020 as compared to the earlier projection of USD 20 billion in 2020

Reprotourism for fertilization treatment across the world is expected to reduce significantly in the next few years due to travel restrictions caused by subsequent COVID-19 waves in developing countries.


The onset of the COVID-19 pandemic led to the suspension of fertility treatments that affected the women psychologically whose treatments were canceled. According to a study published by the American Society for Reproductive Medicine, in October 2020, around 62% of participants desired to begin treatment once the COVID-19 restrictions are eased. Treatment centers are now being permitted to resume treatments with a requirement to adhere to certain guidelines. The Human Fertilization & Embryology Authority permitted to resume treatments in June 2020 and requires individuals infected with COVID-19 to wait for 28 days post-recovery prior to initiating treatment.

Instrument Insights

The in vitro fertilization instrument consists of culture media, capital equipment, and IVF disposable devices. Culture media dominated the market in 2020 and accounted for a revenue share of more than 41%. This growth was credited to the factors, such as the availability of funding and an increase in research activities to improve the culture media. On the other hand, as industry players are introducing disposable devices, such as needles, slides, and chambers, to meet the sterility and regulatory requirements, the disposable devices segment is expected to likely grow at the fastest growth rate during the forecast years.

For instance, in May 2017, CrossBay Medical Inc. received U.S. FDA approval for its CrossBay IVF Embryo Transfer catheter set. The product has also received commercialization approval in Europe and China. Such developments are expected to increase the adoption of disposable IVF devices. Disposable slides for sperm counting, imaging-based tracking system to isolate the best motile sperm, and use of disposable microchips are some of the innovations witnessed by the market in recent years.

Type Insights

The frozen non-donor segment led the global market in 2020. The segment accounted for the maximum revenue share of more than 47% in 2020. The fresh non-donor segment accounted for the second-highest revenue share in 2020. The greater success rate in the first attempt is responsible for the high share of this segment.

As the procedure can be performed even in complicated cases, the segment is also expected to witness the fastest CAGR from 2021 to 2028. For instance, a patient suffering from Ovarian Hyperstimulation Syndrome (OHSS) can opt for this type of IVF procedure. On the basis of type, the global IVF market has been segmented into fresh non-donor, frozen nondonor, fresh donor, and frozen donor.

End-use Insights

The fertility clinics segment dominated the global market accounting for the largest revenue share of more than 79% in 2020. The segment is likely to retain its dominant market position throughout the forecast period growing at the fastest CAGR from 2021 to 2028. With a rise in demand for ART treatments, the number of fertility clinics and ART centers is increasing considerably. Factors, such as cost-effectiveness, availability of specialists, and minimal or no chances of Hospital-Acquired Infections (HAIs), are anticipated to drive the growth of fertility clinics. IVF treatments are also performed in hospitals.

Several multispecialty hospitals offer infertility treatments, including IVF. Increased accessibility and availability of potential treatments can be attributed to higher preference for hospitals for infertility treatments. The IVF treatments offered by hospitals are generally more expensive than fertility clinics. IVF treatments require highly skilled physicians and staff. Hence, employing a dedicated staff for IVF in hospitals is a less preferable approach. The employment, remuneration, and training are expensive in developed countries, such as the U.S. and U.K. All these abovementioned factors can be attributed to the low share of the hospitals segment in the market.

Regional Insights

Europe dominated the global market with a revenue share of more than 37% in 2020. Factors, such as rising medical tourism and legal revisions related to IVF techniques, will propel the regional market growth during the forecast years. An increasing number of people from the U.S. are traveling to the Czech Republic to avail IVF treatments at lower costs. As per an ESHRE fact sheet, in January 2017, some reimbursement is available for ART in almost all EU member states (except Lithuania and Ireland).

Global in vitro fertilization market share, by region, 2020 (%)

The market in Asia Pacific is estimated to register the fastest CAGR from 2021 to 2028. The demand for IVF treatment is expected to increase in the Asia Pacific region due to initiatives to create awareness regarding IVF, change in the regulatory landscape, and fertility tourism.

Key Companies & Market Share Insights

Geographical expansions, mergers, and product innovations & commercialization are the key strategies adopted by the market players. For instance, in July 2019, Vitrolife and Prime Tech entered into a collaboration agreement to design and market the Piezo technique for better Intracytoplasmic Sperm Injection (ICSI) procedure in human IVF globally except for Thailand, Japan, and Malaysia. Some of the prominent players in the global in vitro fertilization market include:

  • OvaScience

  • EMD Serono, Inc.

  • Vitrolife AB

  • Irvine Scientific

  • Cook Medical, Inc.

  • Cooper Surgical, Inc.

  • Genea Biomedx

  • Thermo Fisher Scientific, Inc.

  • Progyny, Inc.

  • Boston IVF

In Vitro Fertilization Market Report Scope

Report Attribute


Market size value in 2021

USD 21.89 billion

Revenue forecast in 2028

USD 33.9 billion

Growth rate

CAGR of 6.46% from 2021 to 2028

Base year for estimation


Historical data

2016 - 2019

Forecast period

2021 - 2028

Quantitative units

Revenue in USD million/billion and CAGR from 2021 to 2028

Report coverage

Revenue forecast, company ranking, competitive landscape, growth factors, and trends

Segments covered

Instrument, type, end-use, region

Regional scope

North America; Europe; Asia Pacific; Latin America; Middle East & Africa

Country scope

U.S.; Canada; France; Germany; Italy; Spain; U.K.; Belgium; The Netherlands; Switzerland; Japan; China; India; Brazil; Mexico; South Africa

Key companies profiled

OvaScience; EMD Serono Inc.; Vitrolife AB; Irvine Scientific; Cook Medical Inc.; Cooper Surgical Inc.; Genea Biomedx; Thermo Fisher Scientific Inc.; Progyny, Inc.; Boston IVF

Customization scope

Free report customization (equivalent up to 8 analysts working days) with purchase. Addition or alteration to country, regional & segment scope.

Pricing and purchase options

Avail customized purchase options to meet your exact research needs. Explore purchase options


Segments Covered in the Report

This report forecasts revenue growth at the global, regional, and country levels and provides an analysis of the latest industry trends in each of the sub-segments from 2016 to 2028. For the purpose of this study, Grand View Research has segmented the global in vitro fertilization market report on the basis of type, end-use, instrument, and region:

  • Type Outlook (Revenue, USD Million, 2016 - 2028)

    • Fresh Non-donor

    • Frozen Non-donor

    • Fresh Donor

    • Frozen Donor

  • End-use Outlook (Revenue, USD Million, 2016 - 2028)

    • Fertility Clinics

    • Hospitals & Others Settings

  • Instrument Outlook (Revenue, USD Million, 2016 - 2028)

    • Culture Media

    • Disposable Devices

    • Capital Equipment

  • Regional Outlook (Revenue, USD Million, 2016 - 2028)

    • North America

      • U.S.

      • Canada

    • Europe

      • France

      • Germany

      • Italy

      • Spain

      • U.K.

      • Belgium

      • The Netherlands

      • Switzerland

    • Asia Pacific

      • Japan

      • China

      • India

    • Latin America

      • Brazil

      • Mexico

    • Middle East & Africa (MEA)

      • South Africa

Frequently Asked Questions About This Report

gvr icn


gvr icn

This FREE sample includes market data points, ranging from trend analyses to market estimates & forecasts. See for yourself...

gvr icn


We can customize every report - free of charge - including purchasing stand-alone sections or country-level reports, as well as offer affordable discounts for start-ups & universities.

Contact us now to get our best pricing.

BBB icon D&B icon

We are GDPR and CCPA compliant! Your transaction & personal information is safe and secure.