In Vivo CRO Market Size, Share & Trends Report

In Vivo CRO Market Size, Share & Trends Analysis Report By Model Type (Rodent Based, Non-rodent Based), By Modality (Small Molecule, Large Molecule), By Indication, By GLP Type (Non GLP, GLP Toxicology), By Region, And Segment Forecasts, 2024 - 2030

  • Report ID: GVR-1-68038-011-8
  • Number of Pages: 257
  • Format: Electronic (PDF)
  • Historical Range: 2018 - 2023
  • Industry: Healthcare

Research Methodology

A three-pronged approach was followed for deducing the in vivo CRO market estimates and forecasts. The process has three steps: information procurement, analysis, and validation. The whole process is cyclical, and steps repeat until the estimates are validated. The three steps are explained in detail below:

Information procurement: Information procurement is one of the most extensive and important stages in our research process, and quality data is critical for accurate analysis. We followed a multi-channel data collection process for in vivo CRO market to gather the most reliable and current information possible.

  • We buy access to paid databases such as Hoover’s and Factiva for company financials, industry information, white papers, industry journals, SME journals, and more.
  • We tap into Grand View’s proprietary database of data points and insights from active and archived monitoring and reporting.
  • We conduct primary research with industry experts through questionnaires and one-on-one phone interviews.
  • We pull from reliable secondary sources such as white papers and government statistics, published by organizations like WHO, NGOs, World Bank, etc., Key Opinion Leaders (KoL) publications, company filings, investor documents, and more.
  • We purchase and review investor analyst reports, broker reports, academic commentary, government quotes, and wealth management publications for insightful third-party perspectives.

Analysis: We mine the data collected to establish baselines for forecasting, identify trends and opportunities, gain insight into consumer demographics and drivers, and so much more. We utilized different methods of in vivo CRO market data depending on the type of information we’re trying to uncover in our research.

  • Market Research Efforts: Bottom-up Approach for estimating and forecasting demand size and opportunity, top-down Approach for new product forecasting and penetration, and combined approach of both Bottom-up and Top-down for full coverage analysis.

  • Value-Chain-Based Sizing & Forecasting: Supply-side estimates for understanding potential revenue through competitive benchmarking, forecasting, and penetration modeling.

  • Demand-side estimates for identifying parent and ancillary markets, segment modeling, and heuristic forecasting.

  • Qualitative Functional Deployment (QFD) Modelling for market share assessment.

Market formulation and validation: We mine the data collected to establish baselines for forecasting, identify trends and opportunities, gain insight into consumer demographics and drivers, and so much more. We utilize different methods of data analysis depending on the type of information we’re trying to uncover in our research.

  • Market Formulation: This step involves the finalization of market numbers. This step on an internal level is designed to manage outputs from the Data Analysis step.

  • Data Normalization: The final market estimates and forecasts are then aligned and sent to industry experts, in-panel quality control managers for validation.

  • This step also entails the finalization of the report scope and data representation pattern.

  • Validation: The process entails multiple levels of validation. All these steps run in parallel, and the study is forwarded for publishing only if all three levels render validated results.

In Vivo CRO Market Categorization:

The in vivo CRO market was categorized into five segments, namely model type (Rodent based, Non-Rodent based), modality (Small Molecules, Large Molecules), indication (Oncology, CNS Conditions, Diabetes, Obesity, Pain management, Autoimmune/inflammation conditions), GLP type (GLP Toxicology, Non GLP), and region (North America, Europe, Asia Pacific, Latin America, and Middle East & Africa).

Segment Market Methodology:

The in vivo CRO market was segmented into model type, modality, indication, GLP type, and region. The demand at a segment level was deduced using a funnel method. Concepts like the TAM, SAM, SOM, etc., were put into practice to understand the demand. We at GVR deploy three methods to deduce market estimates and determine forecasts. These methods are explained below:

Market research approaches: Bottom-up

  • Demand estimation of each product across countries/regions summed up to from the total market.

  • Variable analysis for demand forecast.

  • Demand estimation via analyzing paid database, and company financials either via annual reports or paid database.

  • Primary interviews for data revalidation and insight collection.

Market research approaches: Top-down

  • Used extensively for new product forecasting or analyzing penetration levels.

  • Tool used invoice product flow and penetration models Use of regression multi-variant analysis for forecasting Involves extensive use of paid and public databases.

  • Primary interviews and vendor-based primary research for variable impact analysis.

Market research approaches: Combined

  • This is the most common method. We apply concepts from both the top-down and bottom-up approaches to arrive at a viable conclusion.

Regional Market Methodology:

The in vivo CRO market was analyzed at a regional level. The globe was divided into North America, Europe, Asia Pacific, Latin America, and Middle East & Africa, keeping in focus variables like consumption patterns, export-import regulations, consumer expectations, etc. These regions were further divided into twenty-three countries, namely, the U.S.; Canada; the UK; Germany; France; Italy; Spain; Denmark; Sweden; Norway; Japan; China; India; South Korea; Australia; Thailand; Brazil; Mexico; Argentina; South Africa; Saudi Arabia; UAE; Kuwait.

All three above-mentioned market research methodologies were applied to arrive at regional-level conclusions. The regions were then summed up to form the global market.

In vivo CRO market companies & financials:

The in vivo CRO market was analyzed via companies operating in the sector. Analyzing these companies and cross-referencing them to the demand equation helped us validate our assumptions and conclusions. Key market players analyzed include:

  • IQVIA, Inc. - IQVIA, Inc. offers technology solutions, advanced analytics, and clinical research services in the life sciences sector. Through its transformative technology, advanced analytics and data resources, the company establishes connections throughout the healthcare industry. Its platform, IQVIA Connected Intelligence, provides valuable & rapid insights, empowering customers to enhance the process of developing and bringing innovative medical treatments to market. Moreover, it aims to improve healthcare outcomes for patients.

  • Crown Bioscience - Crown Bioscience, a subsidiary of JSR Life Sciences, operates as a Contract Research Organization (CRO). It offers a comprehensive range of services in immuno-oncology, oncology, and immune-mediated inflammatory diseases, encompassing discovery, preclinical, & translational platforms. The organization’s preclinical models cover in vivo, in vitro, and ex vivo methodologies. It collaborates with clients to assess the effectiveness and pharmacological characteristics of potential drugs prior to clinical development.

  • Taconic Biosciences, Inc. - Taconic Biosciences, Inc. specializes in the production and provision of genetically modified rodent models & related services. The company offers a range of animal solutions, enabling customers to obtain or create custom models and breed, condition, test, & distribute valuable research models across the globe. The company’s expertise lies in genetically engineered rat and mouse models, precise research mouse models, and integrated services for model breeding & design. In addition to three service laboratories and six breeding facilities in Europe and the U.S., Taconic maintains distributor partnerships in Asia and can ship animal models to nearly any location worldwide.

  • PsychoGenics, Inc. - PsychoGenics, Inc. is a CRO focused on preclinical research, specializing in the Central Nervous System (CNS) and orphan disorders. The company offers disease models and extensive preclinical services to support companies in developing advanced therapies for highly debilitating CNS & orphan disorders. It aims to minimize the failure rate in clinical trials and facilitate the discovery of innovative treatments.

  • Evotec SE - Evotec SE is a life sciences company that aims to bring highly efficient and novel therapeutics to patients. Its business model revolves around utilizing a multimodality platform called the Datadriven R&D Autobahn to Cures. This platform is employed for its projects and in collaborations with various partners, including pharmaceutical companies, biotech firms, academic institutions, & other stakeholders in the healthcare sector.

  • Janvier Labs - Janvier Labs is a global supplier of translational research services. The company operates a state-of-the-art production facility for conventional and cutting-edge laboratory rodents intended for biomedical research. In addition, it offers an extensive array of preclinical analysis services associated with its clients’ research needs.

  • Biocytogen - Biocytogen offers comprehensive solutions for advancing next-generation antibody drug development in the biomedical field. Its offerings leverage advanced gene editing technologies and a cutting-edge animal facility. The company has developed an integrated platform that facilitates the efficient discovery and validation of antibody drugs. This platform encompasses multiple components, such as generating animal models, discovering therapeutic antibodies through RenMab mice, and conducting preclinical in vivo & in vitro validation studies.

  • GemPharmatech - GemPharmatech works to advance humanized animal models. The company offers a comprehensive range of services, including customized model development, breeding, phenotyping, and pharmacology, catering to the needs of the biomedical research community. It has curated the world’s largest collection of mouse strains, fostered scientific innovation, and facilitated drug discovery efforts.

  • Charles River Laboratories - Charles River Laboratories is a global provider of products and services to support the drug discovery, development, & safety testing processes for pharmaceutical, biotechnology, & other life sciences companies. It operates through three segments: discovery & safety assessment, research models & services, and manufacturing support. The company serves customers in more than 100 countries and has facilities in North America, Europe, and Asia Pacific.

  • ICON plc - ICON plc assists clients in expediting the development of life-saving drugs and devices while enhancing the overall quality of life. With a presence in 53 countries, the company offers a comprehensive suite of consultation, development, and commercialization services. Its innovation revolves around addressing key factors crucial to client success, including reducing time to market, minimizing costs, and enhancing quality.

Value chain-based sizing & forecasting

Supply Side Estimates

  • Company revenue estimation via referring to annual reports, investor presentations, and Hoover’s.

  • Segment revenue determination via variable analysis and penetration modeling.

  • Competitive benchmarking to identify market leaders and their collective revenue shares.

  • Forecasting via analyzing commercialization rates, pipelines, market initiatives, distribution networks, etc.

Demand side estimates

  • Identifying parent markets and ancillary markets

  • Segment penetration analysis to obtain pertinent

  • revenue/volume

  • Heuristic forecasting with the help of subject matter experts

  • Forecasting via variable analysis

In Vivo CRO Market Report Objectives:

  • Understanding market dynamics (in terms of drivers, restraints, & opportunities) in the countries.

  • Understanding trends & variables in the individual countries & their impact on growth and using analytical tools to provide high-level insights into the market dynamics and the associated growth pattern.

  • Understanding market estimates and forecasts (with the base year as 2022, historic information from 2018 to 2023, and forecast from 2024 to 2030). Regional estimates & forecasts for each category are available and are summed up to form the global market estimates.

In Vivo CRO Market Report Assumptions:

  • The report provides market value for the base year 2022 and a yearly forecast till 2030 in terms of revenue/volume or both. The market for each of the segment outlooks has been provided on region & country basis for the above-mentioned forecast period.

  • The key industry dynamics, major technological trends, and application markets are evaluated to understand their impact on the demand for the forecast period. The growth rates were estimated using correlation, regression, and time-series analysis.

  • We have used the bottom-up approach for market sizing, analyzing key regional markets, dynamics, & trends for various products and end-users. The total market has been estimated by integrating the country markets.

  • All market estimates and forecasts have been validated through primary interviews with the key industry participants.

  • Inflation has not been accounted for to estimate and forecast the market.

  • Numbers may not add up due to rounding off.

  • Europe consists of EU-8, Central & Eastern Europe, along with the Commonwealth of Independent States (CIS).

  • Asia Pacific includes South Asia, East Asia, Southeast Asia, and Oceania (Australia & New Zealand).

  • Latin America includes Central American countries and the South American continent

  • Middle East includes Western Asia (as assigned by the UN Statistics Division) and the African continent.

Primary Research

GVR strives to procure the latest and unique information for reports directly from industry experts, which gives it a competitive edge. Quality is of utmost importance to us, therefore every year we focus on increasing our experts’ panel. Primary interviews are one of the critical steps in identifying recent market trends and scenarios. This process enables us to justify and validate our market estimates and forecasts to our clients. With more than 8,000 reports in our database, we have connected with some key opinion leaders across various domains, including healthcare, technology, consumer goods, and the chemical sector. Our process starts with identifying the right platform for a particular type of report, i.e., emails, LinkedIn, seminars, or telephonic conversation, as every report is unique and requires a differentiated approach.

We send out questionnaires to different experts from various regions/ countries, which is dependent on the following factors:

  • Report/Market scope: If the market study is global, we send questionnaires to industry experts across various regions, including North America, Europe, Asia Pacific, Latin America, and MEA.

  • Market Penetration: If the market is driven by technological advancements, population density, disease prevalence, or other factors, we identify experts and send out questionnaires based on region or country dominance.

The time to start receiving responses from industry experts varies based on how niche or well-penetrated the market is. Our reports include a detailed chapter on the KoL opinion section, which helps our clients understand the perspective of experts already in the market space.

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