MicroRNA (miRNA) Market Size, Share & Trends Report

MicroRNA (miRNA) Market Size, Share & Trends Analysis Report By Research Tools, By Application (Cancer, Neurological Disease, Immunological Disorder, Infectious Diseases) By End-use, And Segment Forecasts, 2018 - 2025

  • Published Date: May, 2018
  • Base Year for Estimate: 2017
  • Report ID: GVR-2-68038-368-3
  • Format: Electronic (PDF)
  • Historical Data: 2014 - 2017
  • Number of Pages: 200

Industry Insights

The global microRNA (miRNA) market size was estimated at USD 160.5 million in 2017. It is projected to rise at a CAGR of 18.6% over the forecast period. Advancements in analytical methods that enable accurate detection & quantification of miRNAs are among the key trends escalating market growth.

U.K. microRNA market

Clinical trials for the application of several miRNAs as biomarkers have received positive results in initial phases and are also under phase II. Significant role of these RNA molecules in regulation of gene expression is encouraging investments in research activities for identification of miRNAs that are involved in tumor formation and their inhibition as an approach to prevent the growth of cancer cells.

For instance, microRNA expression is found to be associated with epithelial-mesenchymal transition, immune system, BRCA mutations, androgen receptor expression, and cancer stem cell properties in triple-negative breast cancer. With further developments in genomic technologies and computational approaches, the market is expected to rise exponentially.

Several microRNA therapeutics, which can potentially indicate for Hepatitis C virus, vascular diseases, peripheral arterial disease, cardio metabolic disease, and different types of cancers, are under different phases of clinical trials. For instance, Miravirsen is the first miRNA therapeutic moving forward to make its entry in the market. The drug is in phase II clinical trials in the U.S., Slovakia, Romania, Poland, Germany, and the Netherlands. High potential demonstrated by therapeutics in preclinical studies using these molecules is anticipated to encourage R&D investments in the coming years. 

Effective and accurate delivery of these molecules to an intracellular site such as cytosol and nucleus is one of the major challenges in the development of potential clinical applications of these molecules in therapeutics. Incorporation of nucleic acid with nano-carrier and chemical modification of nucleic acids are among the approaches being developed to overcome these challenges. However, efficacy and toxicity issues remain significant in non-hepatic delivery in human.

Research Tools Scope Insights

Based on research tools employed, the market can be categorized into services and products. Various products are available based on different workflow steps of research. On the basis of products, consumables is estimated to represent the leading share in the market throughout the forecast period.

Services are segmented into sample collection, miRNA cDNA synthesis, profiling & purification, detection, and functional studies. Extraction of microRNAs from sources other than serum & plasma becomes more challenging due to low concentration of nucleic acids in other body fluid.

Functional studies was at the leading revenue contributor in 2017. Higher adoption of functional studies to investigate the role of different miRNAs in various diseases contributes to the larger share in revenue compared to other services. Highly sophisticated equipment such as NGS and qRT-PCR are required to carry out advanced studies. Microarrays are also one of the key technologies employed in the functional studies of these molecules.

Global microrna market

Development of reliable, robust, and simple detection methods are of great significance to study biological functions of the molecules. Various amplification based techniques are employed for highly sensitive detection of these molecules. These include mass spectrometry (MS), surface-enhanced Raman spectroscopy (SERS), electrochemiluminescence, isothermal amplification, and droplet digital PCR (ddPCR). Identification & detection of novel biomarkers for diseases such as cancer, cardiovascular disease, Parkinson’s, and Alzheimer’s diseases are likely to fuel the demand for miRNA detection.

Application Insights

Research tools are used in detection, quantification, and functional analysis of miRNAs in different health conditions. Identification of significant role of the molecules in transcriptional and translational gene expression is increasing the interest of researchers in these molecules for understanding the cause and mechanism of complicated metabolic & neurological diseases such as cancer, Parkinson’s disease, and Alzheimer’s disease.

The cancer segment dominated the miRNA market in terms of revenue as these RNAs serve as ideal candidates in the form of non-invasive biomarkers. The secretion of microRNAs from cells and their presence in biofluids makes them an ideal marker. Furthermore, these molecules are classified based on their usability at different nodes to detect cancer types. For instance, miR-27b, let-7i, and miR-181b are used in the detection of breast and prostate cancer.

Furthermore, microRNAs are identified with the potential to improve prognostication post cardiac arrest. Ongoing investigations in order to determine the regulation of these molecules in multi-organ damage after cardiac arrest is projected to drive revenue generation in this market.

End-Use Insights

Academic & government research institutes accounted for the leading share in the market in 2017. The growth of the segment can be attributed to rapid adoption of microRNA research tools by universities and research labs. The biotech & pharma companies segment is poised to post the highest CAGR during the forecast period owing to rapid adoption of research tools in translation of scientific knowledge to clinical application.

Regulus Therapeutics, Santaris Pharma, Mirna Therapeutics, and miRagen Therapeutics are some of the major companies involved in development of RNA-based therapeutics. These therapeutics either use miRNA mimics to enhance gene expression or use microRNA inhibitors to suppress gene regulatory activity for treatment of diseases. Investments in the development of techniques & tools to overcome existing challenges in clinical translation of microRNA applications are likely to supplement the growth of the market.

Development, approval, and launch of products for use in hospitals and clinics face various challenges due to reproducibility and reliability issues. Complexity of miRNAs and their low stability further increase the difficulty in their development. However, spiraling demand for precision medicine and early diagnostic tests coupled with potential of these molecules to fulfill this demand has fueled the search of novel approaches & strategies.

Regional Insights

North America is expected to dominate the market throughout the forecast period owing to presence of strong technical support and well-established research infrastructure in genomics, proteomics, oncology, and advanced diagnostics research. Approval of fund through European Union for initiatives such as EpimiRNA consortium is anticipated to contribute to the growth of the market in Europe.

Furthermore, rapid progress in genomic studies and rising adoption of advanced technologies are estimated to stoke the growth of the Asia Pacific market. Local players in Japan and China, such as TaKaRa Bio, are involved in the development of products that includes arrays and kits, thus supplementing the growth of the region.

MicroRNA Market Share Insights

The market is moderately consolidated due to presence of a large number of multinational players that have great experience in the genomics & biotechnology market. These players are involved in joint ventures to develop advanced products.

Prominent players in the market include Thermofisher Scientific (Life Technologies); Agilent Technologies; Merck KGaA; QIAGEN (Exiqon); and NanoString Technologies, Inc. These players are focusing on the development of advanced technologies to improve the quantification, detection, and functional analysis workflows for research.

Report Scope



Base year for estimation


Actual estimates/Historical data

2014 - 2017

Forecast period

2018 - 2025

Market representation

Revenue in USD Million & CAGR from 2017 to 2025

Regional scope

North America, Europe, Asia Pacific, Latin America, MEA

Report coverage

Revenue forecast, company share, competitive landscape, growth factors and trends

Country Scope

U.S., Canada, U.K., Germany, Japan, China, Brazil, South Africa

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Segments Covered in the Report

This report forecasts revenue growth at global, regional, & country levels and provides an analysis of the industry trends in each of the sub-segments from 2014 to 2025. For the purpose of this study, Grand View Research has segmented the global microRNA market report on the basis of research tools, application, end-use, and region:

  • Research Tools Outlook (Revenue, USD Million, 2014 - 2025)

    • Services

      • Sample collection

        • Whole Blood

        • Serum

        • Plasma

      • miRNA cDNA Synthesis

      • Profiling & Purification

      • Detection

      • Functional Studies

        • NGS

        • Microarray

        • Real Time PCR

        • Others

    • Products

      • Instruments

      • Consumables

        • Isolation & Purification

        • Quantification & Detection

        • Functional Analysis

        • Others

  • Application Outlook (Revenue, USD Million, 2014 - 2025)

    • Cancer

    • Infectious Diseases

    • Immunological Disorder

    • Cardiovascular Disease

    • Neurological Disease

    • Others

  • End-use Outlook (Revenue, USD Million, 2014 - 2025)

    • Biotechnology and Pharmaceutical Companies

    • Academic & Government Research Institutes

    • Others

  • Regional Outlook (Revenue, USD Million, 2014 - 2025)

    • North America

    • Europe

    • Asia Pacific

    • Latin America

    • Middle East & Africa

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