mRNA Synthesis Raw Materials Market Size, Share & Trends Analysis Report By Type (Capping Agents, Nucleotides, Plasmid DNA), By Application, By End-user, By Region, And Segment Forecasts, 2023 - 2030
- Report ID: GVR-4-68040-022-4
- Number of Pages: 140
- Format: Electronic (PDF)
- Historical Range: 2018 - 2021
- Industry: Healthcare
Market Segmentation
- mRNA Synthesis Raw Materials Type Outlook (Revenue, USD Million, 2018 - 2030)
- Capping Agents
- Nucleotides
- Plasmid DNA
- Others
- mRNA Synthesis Raw Materials Application Outlook (Revenue, USD Million, 2018 - 2030)
- Therapeutics Production
- Vaccine Production
- Others
- mRNA Synthesis Raw Materials End-user Outlook (Revenue, USD Million, 2018 - 2030)
- Biopharmaceutical & Pharmaceutical Companies
- CROs & CMOs
- Academic & Research Institutions
- mRNA Synthesis Raw Materials Regional Outlook (Revenue, USD Million, 2018 - 2030)
- North America
- North America mRNA Synthesis Raw Materials Market, By Type
- Capping Agents
- Nucleotides
- Plasmid DNA
- Others
- North America mRNA Synthesis Raw Materials Market, By Application
- Therapeutics Production
- Vaccine Production
- Others
- North America mRNA Synthesis Raw Materials Market, By End-user
- Biopharmaceutical & Pharmaceutical Companies
- CROs & CMOs
- Academic & Research Institutions
- U.S.
- U.S. mRNA Synthesis Raw Materials Market, By Type
- Capping Agents
- Nucleotides
- Plasmid DNA
- Others
- U.S. mRNA Synthesis Raw Materials Market, By Application
- Therapeutics Production
- Vaccine Production
- Others
- U.S. mRNA Synthesis Raw Materials Market, By End-user
- Biopharmaceutical & Pharmaceutical Companies
- CROs & CMOs
- Academic & Research Institutions
- U.S. mRNA Synthesis Raw Materials Market, By Type
- Canada
- Canada mRNA Synthesis Raw Materials Market, By Type
- Capping Agents
- Nucleotides
- Plasmid DNA
- Others
- Canada mRNA Synthesis Raw Materials Market, By Application
- Therapeutics Production
- Vaccine Production
- Others
- Canada mRNA Synthesis Raw Materials Market, By End-user
- Biopharmaceutical & Pharmaceutical Companies
- CROs & CMOs
- Academic & Research Institutions
- Canada mRNA Synthesis Raw Materials Market, By Type
- North America mRNA Synthesis Raw Materials Market, By Type
- Europe
- Europe mRNA Synthesis Raw Materials Market, By Type
- Capping Agents
- Nucleotides
- Plasmid DNA
- Others
- Europe mRNA Synthesis Raw Materials Market, By Application
- Therapeutics Production
- Vaccine Production
- Others
- Europe mRNA Synthesis Raw Materials Market, By End-user
- Biopharmaceutical & Pharmaceutical Companies
- CROs & CMOs
- Academic & Research Institutions
- Germany
- Germany mRNA Synthesis Raw Materials Market, By Type
- Capping Agents
- Nucleotides
- Plasmid DNA
- Others
- Germany mRNA Synthesis Raw Materials Market, By Application
- Therapeutics Production
- Vaccine Production
- Others
- Germany mRNA Synthesis Raw Materials Market, By End-user
- Biopharmaceutical & Pharmaceutical Companies
- CROs & CMOs
- Academic & Research Institutions
- Germany mRNA Synthesis Raw Materials Market, By Type
- U.K.
- U.K. mRNA Synthesis Raw Materials Market, By Type
- Capping Agents
- Nucleotides
- Plasmid DNA
- Others
- U.K. mRNA Synthesis Raw Materials Market, By Application
- Therapeutics Production
- Vaccine Production
- Others
- U.K. mRNA Synthesis Raw Materials Market, By End-user
- Biopharmaceutical & Pharmaceutical Companies
- CROs & CMOs
- Academic & Research Institutions
- U.K. mRNA Synthesis Raw Materials Market, By Type
- France
- France mRNA Synthesis Raw Materials Market, By Type
- Capping Agents
- Nucleotides
- Plasmid DNA
- Others
- France mRNA Synthesis Raw Materials Market, By Application
- Therapeutics Production
- Vaccine Production
- Others
- France mRNA Synthesis Raw Materials Market, By End-user
- Biopharmaceutical & Pharmaceutical Companies
- CROs & CMOs
- Academic & Research Institutions
- France mRNA Synthesis Raw Materials Market, By Type
- Italy
- Italy mRNA Synthesis Raw Materials Market, By Type
- Capping Agents
- Nucleotides
- Plasmid DNA
- Others
- Italy mRNA Synthesis Raw Materials Market, By Application
- Therapeutics Production
- Vaccine Production
- Others
- Italy mRNA Synthesis Raw Materials Market, By End-user
- Biopharmaceutical & Pharmaceutical Companies
- CROs & CMOs
- Academic & Research Institutions
- Italy mRNA Synthesis Raw Materials Market, By Type
- Spain
- Spain mRNA Synthesis Raw Materials Market, By Type
- Capping Agents
- Nucleotides
- Plasmid DNA
- Others
- Spain mRNA Synthesis Raw Materials Market, By Application
- Therapeutics Production
- Vaccine Production
- Others
- Spain mRNA Synthesis Raw Materials Market, By End-user
- Biopharmaceutical & Pharmaceutical Companies
- CROs & CMOs
- Academic & Research Institutions
- Spain mRNA Synthesis Raw Materials Market, By Type
- Denmark
- Denmark mRNA Synthesis Raw Materials Market, By Type
- Capping Agents
- Nucleotides
- Plasmid DNA
- Others
- Denmark mRNA Synthesis Raw Materials Market, By Application
- Therapeutics Production
- Vaccine Production
- Others
- Denmark mRNA Synthesis Raw Materials Market, By End-user
- Biopharmaceutical & Pharmaceutical Companies
- CROs & CMOs
- Academic & Research Institutions
- Denmark mRNA Synthesis Raw Materials Market, By Type
- Sweden
- Sweden mRNA Synthesis Raw Materials Market, By Type
- Capping Agents
- Nucleotides
- Plasmid DNA
- Others
- Sweden mRNA Synthesis Raw Materials Market, By Application
- Therapeutics Production
- Vaccine Production
- Others
- Sweden mRNA Synthesis Raw Materials Market, By End-user
- Biopharmaceutical & Pharmaceutical Companies
- CROs & CMOs
- Academic & Research Institutions
- Sweden mRNA Synthesis Raw Materials Market, By Type
- Norway
- Norway mRNA Synthesis Raw Materials Market, By Type
- Capping Agents
- Nucleotides
- Plasmid DNA
- Others
- Norway mRNA Synthesis Raw Materials Market, By Application
- Therapeutics Production
- Vaccine Production
- Others
- Norway mRNA Synthesis Raw Materials Market, By End-user
- Biopharmaceutical & Pharmaceutical Companies
- CROs & CMOs
- Academic & Research Institutions
- Norway mRNA Synthesis Raw Materials Market, By Type
- Europe mRNA Synthesis Raw Materials Market, By Type
- Asia Pacific
- Asia Pacific mRNA Synthesis Raw Materials Market, By Type
- Capping Agents
- Nucleotides
- Plasmid DNA
- Others
- Asia Pacific mRNA Synthesis Raw Materials Market, By Application
- Therapeutics Production
- Vaccine Production
- Others
- Asia Pacific mRNA Synthesis Raw Materials Market, By End-user
- Biopharmaceutical & Pharmaceutical Companies
- CROs & CMOs
- Academic & Research Institutions
- Japan
- Japan mRNA Synthesis Raw Materials Market, By Type
- Capping Agents
- Nucleotides
- Plasmid DNA
- Others
- Japan mRNA Synthesis Raw Materials Market, By Application
- Therapeutics Production
- Vaccine Production
- Others
- Japan mRNA Synthesis Raw Materials Market, By End-user
- Biopharmaceutical & Pharmaceutical Companies
- CROs & CMOs
- Academic & Research Institutions
- Japan mRNA Synthesis Raw Materials Market, By Type
- China
- China mRNA Synthesis Raw Materials Market, By Type
- Capping Agents
- Nucleotides
- Plasmid DNA
- Others
- China mRNA Synthesis Raw Materials Market, By Application
- Therapeutics Production
- Vaccine Production
- Others
- China mRNA Synthesis Raw Materials Market, By End-user
- Biopharmaceutical & Pharmaceutical Companies
- CROs & CMOs
- Academic & Research Institutions
- China mRNA Synthesis Raw Materials Market, By Type
- India
- India mRNA Synthesis Raw Materials Market, By Type
- Capping Agents
- Nucleotides
- Plasmid DNA
- Others
- India mRNA Synthesis Raw Materials Market, By Application
- Therapeutics Production
- Vaccine Production
- Others
- India mRNA Synthesis Raw Materials Market, By End-user
- Biopharmaceutical & Pharmaceutical Companies
- CROs & CMOs
- Academic & Research Institutions
- India mRNA Synthesis Raw Materials Market, By Type
- South Korea
- South Korea mRNA Synthesis Raw Materials Market, By Type
- Capping Agents
- Nucleotides
- Plasmid DNA
- Others
- South Korea mRNA Synthesis Raw Materials Market, By Application
- Therapeutics Production
- Vaccine Production
- Others
- South Korea mRNA Synthesis Raw Materials Market, By End-user
- Biopharmaceutical & Pharmaceutical Companies
- CROs & CMOs
- Academic & Research Institutions
- South Korea mRNA Synthesis Raw Materials Market, By Type
- Australia
- Australia mRNA Synthesis Raw Materials Market, By Type
- Capping Agents
- Nucleotides
- Plasmid DNA
- Others
- Australia mRNA Synthesis Raw Materials Market, By Application
- Therapeutics Production
- Vaccine Production
- Others
- Australia mRNA Synthesis Raw Materials Market, By End-user
- Biopharmaceutical & Pharmaceutical Companies
- CROs & CMOs
- Academic & Research Institutions
- Australia mRNA Synthesis Raw Materials Market, By Type
- Thailand
- Thailand mRNA Synthesis Raw Materials Market, By Type
- Capping Agents
- Nucleotides
- Plasmid DNA
- Others
- Thailand mRNA Synthesis Raw Materials Market, By Application
- Therapeutics Production
- Vaccine Production
- Others
- Thailand mRNA Synthesis Raw Materials Market, By End-user
- Biopharmaceutical & Pharmaceutical Companies
- CROs & CMOs
- Academic & Research Institutions
- Thailand mRNA Synthesis Raw Materials Market, By Type
- Asia Pacific mRNA Synthesis Raw Materials Market, By Type
- Latin America
- Latin America mRNA Synthesis Raw Materials Market, By Type
- Capping Agents
- Nucleotides
- Plasmid DNA
- Others
- Latin America mRNA Synthesis Raw Materials Market, By Application
- Therapeutics Production
- Vaccine Production
- Others
- Latin America mRNA Synthesis Raw Materials Market, By End-user
- Biopharmaceutical & Pharmaceutical Companies
- CROs & CMOs
- Academic & Research Institutions
- Brazil
- Brazil mRNA Synthesis Raw Materials Market, By Type
- Capping Agents
- Nucleotides
- Plasmid DNA
- Others
- Brazil mRNA Synthesis Raw Materials Market, By Application
- Therapeutics Production
- Vaccine Production
- Others
- Brazil mRNA Synthesis Raw Materials Market, By End-user
- Biopharmaceutical & Pharmaceutical Companies
- CROs & CMOs
- Academic & Research Institutions
- Brazil mRNA Synthesis Raw Materials Market, By Type
- Mexico
- Mexico mRNA Synthesis Raw Materials Market, By Type
- Capping Agents
- Nucleotides
- Plasmid DNA
- Others
- Mexico mRNA Synthesis Raw Materials Market, By Application
- Therapeutics Production
- Vaccine Production
- Others
- Mexico mRNA Synthesis Raw Materials Market, By End-user
- Biopharmaceutical & Pharmaceutical Companies
- CROs & CMOs
- Academic & Research Institutions
- Mexico mRNA Synthesis Raw Materials Market, By Type
- Argentina
- Argentina mRNA Synthesis Raw Materials Market, By Type
- Capping Agents
- Nucleotides
- Plasmid DNA
- Others
- Argentina mRNA Synthesis Raw Materials Market, By Application
- Therapeutics Production
- Vaccine Production
- Others
- Argentina mRNA Synthesis Raw Materials Market, By End-user
- Biopharmaceutical & Pharmaceutical Companies
- CROs & CMOs
- Academic & Research Institutions
- Argentina mRNA Synthesis Raw Materials Market, By Type
- Latin America mRNA Synthesis Raw Materials Market, By Type
- Middle East and Africa (MEA)
- Middle East and Africa mRNA Synthesis Raw Materials Market, By Type
- Capping Agents
- Nucleotides
- Plasmid DNA
- Others
- Middle East and Africa mRNA Synthesis Raw Materials Market, By Application
- Therapeutics Production
- Vaccine Production
- Others
- Middle East and Africa mRNA Synthesis Raw Materials Market, By End-user
- Biopharmaceutical & Pharmaceutical Companies
- CROs & CMOs
- Academic & Research Institutions
- South Africa
- South Africa mRNA Synthesis Raw Materials Market, By Type
- Capping Agents
- Nucleotides
- Plasmid DNA
- Others
- South Africa mRNA Synthesis Raw Materials Market, By Application
- Therapeutics Production
- Vaccine Production
- Others
- South Africa mRNA Synthesis Raw Materials Market, By End-user
- Biopharmaceutical & Pharmaceutical Companies
- CROs & CMOs
- Academic & Research Institutions
- South Africa mRNA Synthesis Raw Materials Market, By Type
- Saudi Arabia
- Saudi Arabia mRNA Synthesis Raw Materials Market, By Type
- Capping Agents
- Nucleotides
- Plasmid DNA
- Others
- Saudi Arabia mRNA Synthesis Raw Materials Market, By Application
- Therapeutics Production
- Vaccine Production
- Others
- Saudi Arabia mRNA Synthesis Raw Materials Market, By End-user
- Biopharmaceutical & Pharmaceutical Companies
- CROs & CMOs
- Academic & Research Institutions
- Saudi Arabia mRNA Synthesis Raw Materials Market, By Type
- UAE
- UAE mRNA Synthesis Raw Materials Market, By Type
- Capping Agents
- Nucleotides
- Plasmid DNA
- Others
- UAE mRNA Synthesis Raw Materials Market, By Application
- Therapeutics Production
- Vaccine Production
- Others
- UAE mRNA Synthesis Raw Materials Market, By End-user
- Biopharmaceutical & Pharmaceutical Companies
- CROs & CMOs
- Academic & Research Institutions
- UAE mRNA Synthesis Raw Materials Market, By Type
- Kuwait
- Kuwait mRNA Synthesis Raw Materials Market, By Type
- Capping Agents
- Nucleotides
- Plasmid DNA
- Others
- Kuwait mRNA Synthesis Raw Materials Market, By Application
- Therapeutics Production
- Vaccine Production
- Others
- Kuwait mRNA Synthesis Raw Materials Market, By End-user
- Biopharmaceutical & Pharmaceutical Companies
- CROs & CMOs
- Academic & Research Institutions
- Kuwait mRNA Synthesis Raw Materials Market, By Type
- Middle East and Africa mRNA Synthesis Raw Materials Market, By Type
- North America
mRNA Synthesis Raw Materials Market Dynamics
Drivers: Growing Academic and Industrial Interest in mRNA Technology
Recently, with an approach to encourage therapeutic uses for RNA, particularly In Vitro Transcribed (IVT) mRNA, several RNA centers have been developed at various institutions such as Yale Center for RNA Science and Medicine, RNA Institute at the University at Albany, State University of New York, and the RNA Therapeutic Institute at the University of Massachusetts in the United States. In addition, university supplementary businesses funded by substantial venture capital infusions (such as Argos Medicines, Factor Bioscience, CureVac, Ethris, BioNTech, Moderna, eTheRNA, and Onkaido) have achieved noteworthy advanced states in terms of the preclinical and clinical development of mRNA-based therapeutics. Moreover, to promote and encourage the development of new blood vessels, testing of mRNA treatment is also being done proactively. For instance, AstraZeneca and Moderna have collaborated to explore new possibilities concerning myocardial ischemia therapy using mRNA. In addition, mRNA treatments for cardiovascular diseases are being tested by Arcturus Therapeutics. Thus, many major pharmaceutical firms have started exploring newer horizons in terms of mRNA technology, including Novartis, Alexion, AstraZeneca, Pfizer, Sanofi Pasteur, and Shire. For instance, in January 2022, According to a development and option agreement between Pfizer, Inc. and Acuitas Therapeutics, Pfizer will have the option to license Acuitas’ LNP technology for up to 10 targets for the development of mRNA therapeutics and vaccines. This has led to an increase in the adoption of mRNA synthesis raw materials by pharma & biotech companies, which further results in significant growth for the market.
Driver: Advantages of mRNA Vaccines
Many vaccines deliver pathogenic bacteria to humans through an injection that is weak or inactive to stimulate an immune response. However, in an entirely different scenario of mRNA vaccines, the direction for cells to produce a protein (or perhaps a protein fragment) is generated which further stimulates an immune response using artificial mRNA created in a lab. The chief driver of base editing programmers’ widespread research and use is their several special benefits as mRNA vaccines. Ease of manufacturing is one of the key reasons behind the development of mRNA vaccines. In addition, simple in form, its active component, RNA is often produced in vitro using linear DNA as a template. The stability & translation effectiveness of mRNA can be enhanced through codon optimization, nucleoside modification & an additional delivery method, to create a nucleic acid vaccine with more specificity as well as robust stability. The safety of the vaccine is yet another vital aspect that encourages widespread use. As it does not integrate into the host genome, eliminating any chance of insertion, mutation, or infection, the mRNA can be eliminated by typical cellular processes. Thus, it will propel the overall demand and assist in an increase in acceptance among patient populations and biotech companies for mRNA vaccines which might further boost market growth. For instance, in March 2022, The National Institutes of Health's National Institute of Allergy and Infectious Diseases (NIAID) initiated a Phase 1 clinical trial to evaluate three potential HIV vaccines using an mRNA platform.
Restraint: Absence of Effective Government Regulations for mRNA-Based Product Approvals
When considered in relation to the biotechnology, pharmaceutical, and medical technology industries the regulatory framework for approval processes has always been the most critical restraining factor. Although mRNA-based therapeutics are well embedded in the regulatory system, the European Medicines Agency (EMA) or the Food and Drug Administration (FDA) has not provided RNA-specific guidelines. mRNA is part of a wide-ranging vaccine group of genetic immunogens, hence many guidelines distinct for gene therapy vectors and plasmid DNA vaccines apply to mRNA. However, specific versions are obligatory to reflect the individuality of mRNA. In addition, RNA stability, reactogenicity of RNA, tissue distribution concerns, and potential toxicity pose certain issues of practicality concerning mRNA vaccine development, Hence, mRNA needs effective administrative regulations for mRNA-based product approvals. Furthermore, the lack of effective regulatory framework/guidelines for the therapeutic sector in developing countries, such as China and India, where the mRNA therapeutics market is consolidating noteworthy growth potential owing to the presence of a large patient base, is anticipated to hinder market growth in the upcoming years. Such distinct & unclear circumstances pertaining to the regulations for vaccines & therapeutics approval build confusion among makers regarding the commercialization of mRNA-based products.
What Does This Report Include?
This section will provide insights into the contents included in this mRNA synthesis raw materials market report and help gain clarity on the structure of the report to assist readers in navigating smoothly.
mRNA synthesis raw materials market qualitative analysis
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Industry overview
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Industry trends
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Market drivers and restraints
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Market size
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Growth prospects
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Porter’s analysis
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PESTEL analysis
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Key market opportunities prioritized
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Competitive landscape
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Company overview
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Financial performance
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Product benchmarking
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Latest strategic developments
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mRNA synthesis raw materials market quantitative analysis
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Market size, estimates, and forecast from 2018 to 2030
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Market estimates and forecast for product segments up to 2030
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Regional market size and forecast for product segments up to 2030
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Market estimates and forecast for application segments up to 2030
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Regional market size and forecast for application segments up to 2030
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Company financial performance
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