Nerve Repair And Regeneration Market Size, Share & Trends Report

Nerve Repair And Regeneration Market Size, Share & Trends Analysis Report By Surgery (Nerve Grafting, Neurorrhaphy), By Product (Biomaterials Neurostimulation & Neuromodulation Device), By Region, And Segment Forecasts, 2023 - 2030

  • Report ID: 978-1-68038-961-6
  • Number of Pages: 110
  • Format: Electronic (PDF)
  • Historical Range: 2018 - 2021
  • Industry: Healthcare

Research Methodology

A three-pronged approach was followed for deducing the nerve repair and regeneration market estimates and forecasts. The process has three steps: information procurement, analysis, and validation. The whole process is cyclical, and steps repeat until the estimates are validated. The three steps are explained in detail below:

Information procurement: Information procurement is one of the most extensive and important stages in our research process, and quality data is critical for accurate analysis. We followed a multi-channel data collection process for nerve repair and regeneration market to gather the most reliable and current information possible.

  • We buy access to paid databases such as Hoover’s and Factiva for company financials, industry information, white papers, industry journals, SME journals, and more.
  • We tap into Grand View’s proprietary database of data points and insights from active and archived monitoring and reporting.
  • We conduct primary research with industry experts through questionnaires and one-on-one phone interviews.
  • We pull from reliable secondary sources such as white papers and government statistics, published by organizations like WHO, NGOs, World Bank, etc., Key Opinion Leaders (KoL) publications, company filings, investor documents, and more.
  • We purchase and review investor analyst reports, broker reports, academic commentary, government quotes, and wealth management publications for insightful third-party perspectives.

Analysis: We mine the data collected to establish baselines for forecasting, identify trends and opportunities, gain insight into consumer demographics and drivers, and so much more. We utilized different methods of nerve repair and regeneration market data depending on the type of information we’re trying to uncover in our research.

  • Market Research Efforts: Bottom-up Approach for estimating and forecasting demand size and opportunity, top-down Approach for new product forecasting and penetration, and combined approach of both Bottom-up and Top-down for full coverage analysis.

  • Value-Chain-Based Sizing & Forecasting: Supply-side estimates for understanding potential revenue through competitive benchmarking, forecasting, and penetration modeling.

  • Demand-side estimates for identifying parent and ancillary markets, segment modeling, and heuristic forecasting.

  • Qualitative Functional Deployment (QFD) Modelling for market share assessment.

Market formulation and validation: We mine the data collected to establish baselines for forecasting, identify trends and opportunities, gain insight into consumer demographics and drivers, and so much more. We utilize different methods of data analysis depending on the type of information we’re trying to uncover in our research.

  • Market Formulation: This step involves the finalization of market numbers. This step on an internal level is designed to manage outputs from the Data Analysis step.

  • Data Normalization: The final market estimates and forecasts are then aligned and sent to industry experts, in-panel quality control managers for validation.

  • This step also entails the finalization of the report scope and data representation pattern.

  • Validation: The process entails multiple levels of validation. All these steps run in parallel, and the study is forwarded for publishing only if all three levels render validated results.

Nerve Repair And Regeneration Market Categorization:

The nerve repair and regeneration market was categorized into four segments, namely product (Biomaterials, Neurostimulation and Neuromodulation Devices), surgery (Direct Nerve Repair/Neurorrhaphy, Nerve Grafting, Stem Cell Therapy, Neurostimulation and Neuromodulation Surgeries), and regions (North America, Europe, Asia Pacific, Latin America, Middle East & Africa).

Segment Market Methodology:

The nerve repair and regeneration market was segmented into product, surgery, and regions. The demand at a segment level was deduced using a funnel method. Concepts like the TAM, SAM, SOM, etc., were put into practice to understand the demand. We at GVR deploy three methods to deduce market estimates and determine forecasts. These methods are explained below:

Market research approaches: Bottom-up

  • Demand estimation of each product across countries/regions summed up to from the total market.

  • Variable analysis for demand forecast.

  • Demand estimation via analyzing paid database, and company financials either via annual reports or paid database.

  • Primary interviews for data revalidation and insight collection.

Market research approaches: Top-down

  • Used extensively for new product forecasting or analyzing penetration levels.

  • Tool used invoice product flow and penetration models Use of regression multi-variant analysis for forecasting Involves extensive use of paid and public databases.

  • Primary interviews and vendor-based primary research for variable impact analysis.

Market research approaches: Combined

  • This is the most common method. We apply concepts from both the top-down and bottom-up approaches to arrive at a viable conclusion.

Regional Market Methodology:

The nerve repair and regeneration market was analyzed at a regional level. The globe was divided into North America, Europe, Asia Pacific, Latin America, and Middle East & Africa, keeping in focus variables like consumption patterns, export-import regulations, consumer expectations, etc. These regions were further divided into twenty-five countries, namely, the U.S.; Canada; UK.; Germany; France; Italy; Spain; Denmark; Norway; Sweden; India; Singapore; South Korea; China; Japan; India; Australia; Thailand; Brazil; Mexico; Argentina; South Africa; Saudi Arabia; UAE; Kuwait

All three above-mentioned market research methodologies were applied to arrive at regional-level conclusions. The regions were then summed up to form the global market.

Nerve repair and regeneration market companies & financials:

The nerve repair and regeneration market was analyzed via companies operating in the sector. Analyzing these companies and cross-referencing them to the demand equation helped us validate our assumptions and conclusions. Key market players analyzed include:

  • NeuroPace, Inc. is a privately held company, established in 1997, that designs, develops, manufactures, and commercializes implantable devices for the treatment of neurological disorders. The company mainly provides treatment for patients suffering from epilepsy who do not respond to medication. Its RNS System is an award-winning technology developed and manufactured in Silicon Valley. In March 2020, NeuroPace, Inc. received approval from the U.S. FDA for MRI labeling for its Responsive Neurostimulation Device (RNS) system. This approval will expand treatment options for more than one million patients suffering from seizures who do not respond to medication in the United States.
  • Medtronic is a global health solutions company, established in 1949, and headquartered in Ireland, is engaged in the development, manufacture, and commercialization of device-based medical therapies & services. It operates through four reportable segments: cardiac & vascular group, minimally invasive therapies, restorative therapies, and diabetes group. Its cardiac surgery products consist of positioning and stabilization systems for beating heart surgery. The company carried forward its innovation in the surgical space facilitated by robotic and automated technologies. Its neurological segment offers infusion therapies, neurostimulation, and drug pumps for chronic pain. Its brain therapy divisions market an integrated portfolio of devices for the treatment of neurological disorders and surgical technologies designed to improve the workflow of neurosurgical procedures. Its products include neurovascular stents, coils, and flow diversion products, as well as access and delivery products to support neurosurgical procedures.
  • Stryker is a medical technology company, founded in 1946 which now has an employee strength of 46,000 people, and offers innovative products and services in medical and surgical, neurotechnology, orthopedics, and spine. The company operates in two key reportable business segments namely MedSurg and Neurotechnology, and Orthopedics and Spine. The firm's nerve portfolio entails type I collagen conduits and wraps. They are intended to provide a protective layer around injured peripheral nerves and offer a resorbable and semi-permeable encasement to facilitate nerve repair. The company has a strong presence in regions, such as the U.S., Europe, Asia Pacific, Japan, and Middle East countries. It has an existence in more than 75 countries through its distributor network. It has a training portal for medical professionals and patients as well that delivers the necessary amount of information about the procedures. The company has collaborated with organizations such as the American Association of Hip and Knee Surgeons, The Medical Devices Manufacturing Association, and the National Electrical Equipment Manufacturers Association to promote the perception of medical technology and its impact on customers.
  • AxoGen Corporation, founded in the year 2002, is operating in areas such as manufacturing and marketing of peripheral nerve repair and reconstruction products. The products are adopted by hand surgeons, reconstructive plastic surgeons, and oral and maxillofacial surgeons in a wide range of nerve repair surgeries. Some of the solutions and systems are Avance Nerve Graft, AxoGuard Nerve Connector, AxoGuard Nerve Protector, Avive Soft Tissue Membrane, AcroVal neurosensory and motor testing system, AcroPinch and AxoTouch. AxoGen’s regenerative product portfolio is available in the U.S., the UK, Canada, South Korea, and other European and international countries.
  • Abbott is a healthcare industry leader involved in the discovery, development, manufacture, and sale of diverse healthcare products. The entity was founded back in 1900 in the United States and now has a worldwide presence with an employee strength of 113,000 The company has four reportable segments: Established Pharmaceutical Products, Diagnostic Products, Nutritional Products, and Medical Devices. The company offers products in key sectors: cardiovascular, diabetes, diagnostics, neuromodulation, nutrition, and pharmaceuticals. The company serves more than 160 countries across the globe.
  • Baxter, which was established back in 1931, in the United States, which was operating with an employee strength of 60,000 people in 2021, manufactures and distributes products & technologies for kidney diseases, infectious diseases, hemophilia, immune disorders, trauma, and other chronic & acute medical conditions. It develops products in numerous segments, such as advanced surgery, pharmaceuticals, clinical nutrition, renal care, medication delivery, and acute therapies. Baxter also focuses on medical devices, pharmacy automation, anesthetics, and bio-surgery & wound care solutions. SYNOVIS MICRO COMPANIES ALLIANCE, INC is a subsidiary of Baxter International and was founded in the year 2000. The company is dedicated to reconstructive microsurgeon advancements in services and products. The company provides its services in plastic reconstructive, microsurgery, head & neck, hand extremity, lymphatic, orthopedic, and trauma. At the end of 2021, Baxter International had around 53 production sites worldwide.
  • Boston Scientific Corporation, formed back in 1979, and headquartered in the United States, is in the business of designing, manufacturing, and marketing a wide range of medical devices, that are used in different medical interventional therapies. The firm's core business is organized into three reportable segments: MedSurg, Rhythm and Neuro, and Cardiovascular. In 2021, the company marketed its products and solutions to approximately 35,000 hospitals, clinics, outpatient facilities, and medical offices in more than 120 countries worldwide. The firm has its research and development capabilities in locations such as Canada, China, Costa Rica, India, Ireland, and Israel, and provides localized training programs through our Institutes for Advancing Science (IAS) facilities around the world. In January 2021, Boston Scientific Corporation received U.S. FDA approval for its fourth-generation Vercise Genus Deep Brain Stimulation (DBS) System. In September 2020, Boston Scientific Corporation received a CE Mark and initiated a limited market release of the 4th generation Vercise Genus Deep Brain Stimulation (DBS) System in Europe.
  • Polyganics is a medical technology company, founded in 1999 and headquartered in the Netherlands, involved in developing, manufacturing, and commercialization of bioresorbable medical devices. Polyganics’ current portfolio includes devices developed for leading medical technology companies and in-house devices that facilitate the regeneration and repair of natural tissues. Surgical applications for the products include peripheral nerve repair, neuro nerve repair as well as nose, ear & throat surgery. The ENT business of the firm was acquired by Stryker in 2014. The company has a broad technology platform based on proprietary polymers and adhesives. In April 2021, Polyganics, opened a new state-of-the-art, purpose-built facility on the Zernike Campus, Groningen. The firm’s research laboratories, production and packaging facilities, and offices will all be housed in the new facility
  • Integra LifeSciences, the company established in 1989, and headquartered in the United States, is a technology company that develops cutting-edge regenerative tissue technologies and neurosurgical treatments. Codman Specialty Surgical (CSS) and Tissue Technology are two reportable business sectors that manufacture and market medical technologies and products (TT). CSS comprises technology and apparatus utilized in a wide range of specialties, including neurosurgery, neurocritical care, and otolaryngology, and accounts for two-thirds of overall revenue. The TT section accounts for nearly a third of total revenue and is divided into three categories: difficult wound surgery, surgical reconstruction, and peripheral nerve treatment. In March 2022, Integra LifeSciences launched NeuraGen 3D Nerve Guide Matrix, a resorbable implant for the repair of peripheral nerve discontinuities. In September 2019, Integra LifeSciences acquired Rebound Therapeutics, which helped the company develop innovative products to address unmet needs in neurosurgery.

Value chain-based sizing & forecasting

Supply Side Estimates

  • Company revenue estimation via referring to annual reports, investor presentations, and Hoover’s.

  • Segment revenue determination via variable analysis and penetration modeling.

  • Competitive benchmarking to identify market leaders and their collective revenue shares.

  • Forecasting via analyzing commercialization rates, pipelines, market initiatives, distribution networks, etc.

Demand side estimates

  • Identifying parent markets and ancillary markets

  • Segment penetration analysis to obtain pertinent

  • revenue/volume

  • Heuristic forecasting with the help of subject matter experts

  • Forecasting via variable analysis

Nerve Repair And Regeneration Market Report Objectives:

  • Understanding market dynamics (in terms of drivers, restraints, & opportunities) in the countries.

  • Understanding trends & variables in the individual countries & their impact on growth and using analytical tools to provide high-level insights into the market dynamics and the associated growth pattern.

  • Understanding market estimates and forecasts (with the base year as 2022, historic information from 2018 - 2021, and forecast from 2023 to 2030). Regional estimates & forecasts for each category are available and are summed up to form the global market estimates.

Nerve Repair And Regeneration Market Report Assumptions:

  • The report provides market value for the base year 2022 and a yearly forecast till 2030 in terms of revenue/volume or both. The market for each of the segment outlooks has been provided on region & country basis for the above-mentioned forecast period.

  • The key industry dynamics, major technological trends, and application markets are evaluated to understand their impact on the demand for the forecast period. The growth rates were estimated using correlation, regression, and time-series analysis.

  • We have used the bottom-up approach for market sizing, analyzing key regional markets, dynamics, & trends for various products and end-users. The total market has been estimated by integrating the country markets.

  • All market estimates and forecasts have been validated through primary interviews with the key industry participants.

  • Inflation has not been accounted for to estimate and forecast the market.

  • Numbers may not add up due to rounding off.

  • Europe consists of EU-8, Central & Eastern Europe, along with the Commonwealth of Independent States (CIS).

  • Asia Pacific includes South Asia, East Asia, Southeast Asia, and Oceania (Australia & New Zealand).

  • Latin America includes Central American countries and the South American continent

  • Middle East includes Western Asia (as assigned by the UN Statistics Division) and the African continent.

Primary Research

GVR strives to procure the latest and unique information for reports directly from industry experts, which gives it a competitive edge. Quality is of utmost importance to us, therefore every year we focus on increasing our experts’ panel. Primary interviews are one of the critical steps in identifying recent market trends and scenarios. This process enables us to justify and validate our market estimates and forecasts to our clients. With more than 8,000 reports in our database, we have connected with some key opinion leaders across various domains, including healthcare, technology, consumer goods, and the chemical sector. Our process starts with identifying the right platform for a particular type of report, i.e., emails, LinkedIn, seminars, or telephonic conversation, as every report is unique and requires a differentiated approach.

We send out questionnaires to different experts from various regions/ countries, which is dependent on the following factors:

  • Report/Market scope: If the market study is global, we send questionnaires to industry experts across various regions, including North America, Europe, Asia Pacific, Latin America, and MEA.

  • Market Penetration: If the market is driven by technological advancements, population density, disease prevalence, or other factors, we identify experts and send out questionnaires based on region or country dominance.

The time to start receiving responses from industry experts varies based on how niche or well-penetrated the market is. Our reports include a detailed chapter on the KoL opinion section, which helps our clients understand the perspective of experts already in the market space.

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