Polymerase Chain Reaction Market Size, Share & Trends Report

Polymerase Chain Reaction Market Size, Share & Trends Analysis Report By Type, By Product (Instruments, Consumables & Reagents, Software & Services), By Application, By Region, And Segment Forecasts, 2020 - 2027

  • Published Date: Nov, 2020
  • Base Year for Estimate: 2019
  • Report ID: GVR-4-68039-188-0
  • Format: Electronic (PDF)
  • Historical Data: 2016 - 2018
  • Number of Pages: 161

Report Overview

The global polymerase chain reaction market size was valued at USD 4.5 billion in 2019 and is expected to expand at a compound annual growth rate (CAGR) of 17.5% from 2020 to 2027. One of the major factors driving the market is the increasing demand for advanced diagnostic techniques, prenatal genetic testing procedures, and the rising number of CROs, and forensic and research laboratories owing to their accuracy, automation, precision, real-time quantification, and sensitivity.

U.S. polymerase chain reaction market size, by type, 2016 - 2027 (USD Billion)

In addition, increased availability of government funding for conducting research based on genomics is anticipated to accelerate market growth. For instance, in 2018, Genomics Medicine Ireland (GMI) received funding of USD 413.91 million for conducting genomics research in Ireland. This allowed the researchers to scale up to over 60 areas of diseases.

Furthermore, the launch of novel technologies to strengthen their portfolios and offer innovations to customers are expected to propel market growth over the forecast period. For instance, in April 2019, Thermo Fisher Scientific, Inc. launched the first smart qPCR instruments: Applied Biosystems QuantStudio 6 & 7 Pro Real-Time PCR Systems.

In addition, polymerase chain reaction (PCR) used in pathogen testing is expected to fuel market growth owing to its ability to detect certain pathogens that are required to protect the health of a human. For instance, in November 2019, PathogenDx, Inc. released results on a study that focused on the effectiveness & accuracy of different microbial testing methods for cannabis. The study found that end-point PCR was accurate in detecting the presence of pathogens such as E. coli and Salmonella in cannabis.

Type Insights

The other segment dominated the polymerase chain reaction market and accounted for the largest revenue share of 69.3% in 2019. Other types of PCR consist of real-time PCR (qPCR), digital PCR (dPCR), multiplex, and ultrafast PCR. One of the factors responsible for the dominance of this segment is the increasing adoption of qPCR and dPCR due to their rapid detection of infections and pathogens, as compared to conventional technologies. Other factors favoring this segment include higher sensitivity and resolution, the scope for automation, and high usage in gene expression analysis and genotyping as a validation tool.

In addition, the development and launch of new technologies in this segment are expected to accelerate segment growth over the forecast period. This includes plasmonic PCR, which is a low-cost solution that can detect infections and pathogens faster than the existing PCR technologies.

Product Insights

The consumables and reagents segment accounted for the largest revenue share of 62.2% in 2019, owing to significant demand for genetic testing and availability of technologically advanced diagnostic tests in countries with unmet clinical needs. In addition, the launch of new products is likely to contribute to the growth of the segment. For instance, in March 2018, Biocore Co. Ltd. introduced the first dPCR-based NIPT kits for the diagnosis of chromosomal abnormalities.

Various instruments include QuantStudio 3 & 5 Real-Time PCR Systems and 7500 Fast & 7500 Real-Time PCR System by Thermo Fisher Scientific, Inc.; QuantStudio 3D dPCR System & CFX96 by Bio-Rad Laboratories, Inc.; SmartCycler by Cepheid, Rotor-Gene Q by QIAGEN, LightCycler 2.0, Cobas 4800, & Light Cycler 480 by Roche Molecular Systems, Inc. The advantages offered by these instruments include specificity, sensitivity, and automation during the development of point-of-care diagnostics.

Application Insights

The medical segment accounted for the largest revenue share of 77.5% in 2019 and is anticipated to maintain its dominance over the forecast period. This growth is due to its advantages in research and other applications, such as detecting and quantifying low-frequency mutations and low levels of pathogens with higher sensitivity. Moreover, increasing the adoption of PCR in diagnostic centers and hospitals is propelling segment growth.

Global polymerase chain reaction market share, by application, 2019 (%)

Furthermore, increasing research collaborations coupled with initiatives are expected to contribute to the PCR market growth. In May 2020, Xiamen University, in collaboration with the Chinese University of Hong Kong and the University of Connecticut, was engaged in the development of an experimental procedure for developing and validating a qPCR assay for the detection of Symbiodiniaceae genera. Furthermore, sxtA-based qPCR tests were proved to be effective against Alexandrium catenella in 2019.

Increasing adoption of PCR for food safety, water contamination, and detecting infection & pathogens in environmental and agriculture sample is expected to boost the market growth. For instance, TaqMan Environmental Master Mix 2.0 amplify & analyze (cDNA) complementary DNA and DNA targets in various environmental samples. The assay can be performed on StepOne or StepOnePlus Real-Time PCR System, and Applied Biosystems’ 7300/7500/7500 Fast Real-Time PCR System & 7900HT/7900HT Fast Real-Time PCR System.

Regional Insights

North America dominated the market and accounted for the largest revenue share of 44.8% in 2019. Favorable government initiatives coupled with flexible regulatory guidelines are anticipated to propel market growth in the region. For instance, in February 2020, the Department of Health and Human Services announced the authorization of the emergency use of diagnostics for the detection of COVID-19. This authorization increased the number of diagnostics product launches in the region.

The Asia Pacific is estimated to be the fastest-growing segment over the forecast period owing to the increasing utilization of medical tests to detect SARS-CoV-2. For instance, as of 9th October 2020, approximately 2.3 million people had undergone PCR tests in Japan. Till April 2020, there were only 0.2 million people who had used PCR tests for COVID-19. Furthermore, the provisional approval of kits to detect COVID-19 is expected to boost the market during the forecast period. For instance, around 34 PCR tests have received provisional authorization from Singapore’s Health Sciences Authority.

Key Companies & Market Share Insights

Key companies are stressing on R&D to develop advanced technology products to gain a competitive edge. Companies are engaging in partnerships, mergers, and acquisitions, aiming to strengthen their product portfolio, manufacturing capacities, and provide competitive differentiation. In January 2017, Bio-Rad acquired RainDance Technologies to strengthen its position in the market. RainDance Technologies markets products for sample enrichment of dPCR. Some of the prominent players in the polymerase chain reaction market include:

  • Abbott

  • Qiagen

  • Thermo Fisher Scientific, Inc.

  • Bio-Rad Laboratories, Inc.

  • BioMérieux SA

  • F. Hoffmann-La Roche Ltd

  • Agilent Technologies, Inc.

  • Fluidigm Corporation

Polymerase Chain Reaction Market Report Scope

Report Attribute


Market size value in 2020

USD 11.3 billion

Revenue forecast in 2027

USD 16.2 billion

Growth Rate

CAGR of 17.5% from 2020 to 2027

Base year for estimation


Historical data

2016 - 2018

Forecast period

2020 - 2027

Quantitative units

Revenue in USD million and CAGR from 2020 to 2027

Report coverage

Revenue forecast, company ranking, competitive landscape, growth factors, and trends

Segments covered

Type, product, application, region

Regional scope

North America; Europe; Asia Pacific; Latin America; MEA

Country scope

U.S.; Canada; U.K.; Germany; France; Spain; Italy; China; Japan; India; South Korea; Australia; Brazil; Mexico; Argentina; South Africa; Saudi Arabia; UAE

Key companies profiled

Thermo Fisher Scientific Inc.; Bio-Rad Laboratories, Inc.; QIAGEN; F. Hoffmann-La Roche Ltd.; Abbott Laboratories; Cepheid, Agilent Technologies, Inc.;  SA; GE Healthcare; Stilla; Microsynth AG; JN Medsys; Fluidigm Corporation

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Segments Covered in the Report

This report forecasts revenue growth at global, regional, and country levels and provides an analysis of the latest industry trends in each of the sub-segments from 2016 to 2027. For the purpose of this study, Grand View Research has segmented the global polymerase chain reaction market report on the basis of type, product, application, and region:

  • Type Outlook (Revenue, USD Million, 2016 - 2027)

    • Conventional PCR

    • Others

  • Product Outlook (Revenue, USD Million, 2016 - 2027)

    • Consumables & Reagents

    • Instruments

    • Software & Services

  • Application Outlook (Revenue, USD Million, 2016 - 2027)

    • Medical

      • Clinical

        • Pathogen Testing

        • Oncology testing

        • Blood Screening

        • Others

      • Research

      • Forensic and others

    • Non-Medical

      • Food

      • Others

  • Regional Outlook (Revenue, USD Million, 2016 - 2027)

    • North America

      • U.S.

      • Canada

    • Europe

      • Germany

      • U.K.

      • France

      • Italy

      • Spain

    • Asia Pacific

      • China

      • India

      • Japan

      • South Korea

      • Australia

    • Latin America

      • Brazil

      • Mexico

      • Argentina

    • Middle East & Africa

      • South Africa

      • Saudi Arabia

      • UAE

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