Vitamin K2 Supplements Market Size, Share & Trends Analysis Report By Product (MK-7 Supplements, MK-4 Supplements), By Application (Bone & Joint Health, Cardiovascular Health, General Health), By Distribution Channel, By Region, And Segment Forecasts, 2024 - 2030

Vitamin K2 Supplement Market Trends

The global vitamin K2 supplements market size was valued at USD 1,362.0 million in 2023 and is expected to grow at a CAGR of 12.3% from 2024 to 2030. This is primarily driven by rising consumer awareness of its health benefits for bone and cardiovascular health. The increasing prevalence of osteoporosis and cardiovascular diseases, particularly among aging populations, is fueling demand for supplements that improve calcium metabolism and prevent arterial calcification. Additionally, advancements in clinical research are driving the market growth.

The market growth is driven by increasing awareness of Vitamin K2's critical role in bone health and cardiovascular health, particularly in preventing calcium deposits in arteries. Supported by strong clinical evidence, Vitamin K2 is gaining traction in the dietary supplement market, with a 30% increase in new product launches since 2015. The growing demand for supplements featuring the longer-lasting MK-7 form of K2 has further boosted market growth, as it offers enhanced bioavailability and effectiveness.

The market is experiencing notable growth, driven by increasing consumer awareness of its benefits, especially when combined with Vitamin D3. Products like Petrovax Pharm's SunDevit supplements, which combine these vitamins, are gaining traction due to their ability to improve calcium distribution, enhance bone mineralization, and prevent calcium buildup in soft tissues and blood vessels. As Vitamin D deficiency becomes more widespread, the demand for supplements that offer a comprehensive approach to calcium metabolism, immune support, and overall health, like vitamin D3 + vitamin K2 supplements, is expected to rise.

A 2023 review of 4,965 elderly individuals titled ‘Association of vitamin K, fibre intake and progression of periodontal attachment loss in American adults’ found that regular vitamin K2 supplementation, combined with moderate fiber intake, was effective in preventing tooth loss due to periodontal disease, especially in males. The benefit was less clear for Black participants, highlighting the need for more research. Vitamin K2 likely influences dental health through its activation of osteocalcin, a protein that supports both bone and dentin formation. Research also shows that vitamins A and D work together with vitamin K2 in maintaining dental health.

Product Insights

MK-7 supplements accounted for a revenue share of 85.3% in 2023, largely driven by its superior bioavailability and longer half-life compared to other forms like MK-4. MK-7’s extended presence in the bloodstream allows it to better support bone health and reduce arterial calcification, making it a preferred choice for consumers and healthcare professionals. Additionally, the growing awareness of MK-7's role in preventing cardiovascular diseases and osteoporosis has fueled its demand, particularly in aging populations and regions with high preventive healthcare adoption.

MK-4 vitamin supplements demand is projected to grow at a CAGR of 11.0% from 2024 to 2030. This is attributed to its recognized role in promoting bone health and cardiovascular function, particularly for short-term therapeutic use. MK-4 is known for its rapid absorption and effectiveness in supporting bone mineralization, making it popular in specific clinical and therapeutic applications. Additionally, growing interest in targeted supplementation, especially for conditions like osteoporosis and arterial calcification, is driving demand for MK-4 supplements.

Application Insights

Vitamin K2 supplement sales for bone & joint health held a revenue share of more than 50% in the global vitamin K2 supplements market in 2023.Vitamin K2 has been shown to play a crucial role in bone health by improving calcium metabolism. Vitamin K2 supports bone health by activating two key proteins: matrix GLA protein and osteocalcin. These proteins are crucial for calcium binding, which helps in building and maintaining strong bones.A 2022 meta-analysis of 16 studies involving 6,425 postmenopausal women found that vitamin K2 supplements positively impacted bone mineralization and strength.

Vitamin K2 supplement demand for cardiovascular health is projected to grow at a CAGR of 13.3% from 2024 to 2030. Recent evidence highlights vitamin K2's potential in cardiovascular health, with research highlighting its ability to improve arterial flexibility and reduce arterial calcification. Vitamin K2, specifically MK-7, supports heart health by activating Matrix GLA Protein (MGP) and may lead to significant healthcare cost savings. A 2023 study found that daily MK-7 supplementation improved vessel elasticity and blood pressure, particularly in women.

Distribution Channel Insights

Pharmacies & drugstore driven vitamin K2 supplement sales accounted for a revenue share of more than 38% in 2023.This is due to their extensive customer reach and established trust in providing health-related products. These outlets offer convenient access and professional guidance, driving consumer confidence and purchasing in this segment. Additionally, their ability to stock a range of supplements supports higher sales volumes.

Online sales of vitamin K2 supplements are projected to grow at a CAGR of 13.4% from 2024 to 2030 due to the increasing preference for convenient shopping and the expansion of e-commerce platforms. The growing trend of purchasing health products online, along with enhanced digital marketing and accessibility, is driving this growth. Additionally, online platforms offer a wider range of products and competitive pricing, attracting more consumers to shop for supplements online.

Regional Insights

The market in North America accounted for a revenue share of 36.7% in 2023 owing to strong consumer focus on cardiovascular and bone health, driven by rising health awareness and preventive healthcare trends. The region benefits from extensive retail and e-commerce infrastructure, facilitating widespread access to vitamin K2 products. Additionally, substantial investments in health research and growing interest in personalized nutrition further contribute to the high market share, reflecting the region's advanced healthcare landscape and consumer willingness to invest in high-quality supplements.

U.S. Vitamin K2 Supplements Market Trends

The vitamin K2 supplement market in the U.S. is expected to grow at a CAGR of 12.5% from 2024 to 2030. This is attributed to increasing awareness of its cardiovascular benefits and the potential for substantial healthcare cost savings. The Council for Responsible Nutrition anticipates that broader use of vitamin K2 could reduce coronary artery disease events by 15.7% and save the U.S. healthcare system USD 9.48 billion annually.

Europe Vitamin K2 Supplements Market Trends

The vitamin K2 supplement market in Europe is expected to grow at a CAGR of 12.0% from 2024 to 2030, largely driven by the region's aging population. With Europe having one of the highest proportions of elderly individuals-nearly 20% of the population is over 65 years old-the demand for supplements that support bone and cardiovascular health is increasing. This demographic shift is prompting a surge in interest for vitamin K2, as it is believed to help mitigate age-related health issues such as osteoporosis and arterial calcification, leading to higher consumption and market growth.

Asia Pacific Vitamin K2 Supplements Market Trends

The vitamin K2 supplement market in Asia Pacific is expected to grow at a CAGR of 13.4% from 2024 to 2030, due to rising health consciousness and increasing disposable incomes in the region.As consumers in the region become more health-conscious and seek proactive approaches to maintaining their well-being, the demand for vitamin K2 supplements that support overall health-including bone strength, cardiovascular function, and metabolic balance-is increasing.

Key Vitamin K2 Supplements Company Insights

The market is moderately fragmented. Key market participants are focusedon product innovation, such as developing high-potency MK-7 formulations and enhancing bioavailability to differentiate themselves in the market. Strategic partnerships, mergers, and acquisitions are also prevalent as they aim to expand their market reach and capabilities. Additionally, investments in research and development to validate health benefits and improve consumer education are some of the crucial strategies driving the growth of key companies giving them competitive advantage.

Recent Developments

• In February 2024, ILSI Europe, launched a new Task Force on Vitamin K2 Supplements, aiming to advance scientific understanding and public awareness of its health benefits. Comprising experts from leading companies and academia, the Task Force will critically review evidence, identify biomarkers, and assess healthcare cost savings, potentially boosting awareness and market growth for Vitamin K2 supplements.

• In April 2023, Petrovax Pharm, a biotech company launched SunDevit, a new vitamin complex combining D3 and K2 in Russia. This innovative product enhances calcium distribution for bone health while preventing calcium buildup in blood vessels. The product supports the immune system, muscles, bones, and joint health. SunDevit is designed for adults and offers an optimal dosage of 2000 IU of vitamin D3 per serving.

Vitamin K2 Supplements Market Report Scope

Global Vitamin K2 Supplements Market Report Segmentation

This report forecasts revenue growth at the global, regional, and country levels and provides an analysis of the latest industry trends and opportunities in each of the sub-segments from 2018 to 2030. For the purpose of this study, Grand View Research has segmented the global vitamin K2 supplements market report on the basis of product, application, distribution channel, and region.

• Product Outlook (Revenue, USD Million, 2018 - 2030)

  • MK-7 Supplements

  • MK-4 Supplements

• Application Outlook (Revenue, USD Million, 2018 - 2030)

  • Bone & Joint Health

  • Cardiovascular Health

  • General Health

  • Others

• Distribution Channel Outlook (Revenue, USD Million, 2018 - 2030)

  • Supermarkets & Hypermarkets

  • Pharmacies & Drugstores

  • Online

  • Others

• Regional Outlook (Revenue, USD Million, 2018 - 2030)

  • North America

    • U.S.

    • Canada

    • Mexico

  • Europe

    • Germany

    • UK

    • France

    • Italy

    • Spain

  • Asia Pacific

    • China

    • India

    • Japan

    • Australia

    • South Korea

  • Central & South America

    • Brazil

  • Middle East & Africa

    • South Africa