GVR Report cover Antifreeze Proteins Market Size, Share & Trends Report

Antifreeze Proteins Market Size, Share & Trends Analysis Report By Form (Solid, Liquid), By Type (Type I, Type III, Antifreeze Glycoprotein), By End-use (Medical, Food, Cosmetics), By Source, By Region, And Segment Forecasts, 2022 - 2028

  • Report ID: GVR-4-68039-938-7
  • Number of Pages: 85
  • Format: Electronic (PDF)

Report Overview

The global antifreeze proteins market size was valued at USD 6.4 million in 2021 and is expected to expand at a CAGR of 27.5% from 2022 to 2028, owing to the rising medical experiment and application of antifreeze proteins in the pharmaceuticals sector. In addition, the rising demand for frozen foods is expected to drive further market growth during the forecast period. Growing usage of developed proteins in skincare products such as anti-aging creams is further expected to propel the market growth during the projected timeline. The rising demand for healthy food & beverage products containing protein ingredients across the globe additionally acts as one of the major motivating factors in the market demand.

 U.S. antifreeze protein market size, by form, 2019 - 2028 (USD Million)

Owing to the COVID-19 pandemic, the demand for the product has decreased. With the ongoing lockdown, the production and supply chain of antifreeze proteins have been affected, thus hampering the growth of the market. During the COVID-19 pandemic, the healthcare experts recommended a daily intake of nutritional food to maintain the immunity of the body, which further increases the demand for protein intake in food across the globe. Therefore, the significant demand for dietary food during the pandemic positively influenced the global market.

Increasing investments from Norway-based aquaculture companies to procure frozen products is refueling the market growth. The companies are focusing on the premium taste of smoked fish with the perfect texture. Rapidly growing demand for aurora salmon from the U.K consumers is propelling the industry growth. Additionally, key players are focusing to launch cost-effective organic salmon food products. Hence, the market is expected to capture significant market growth during the forecast period.

Factors such as improvement of aquaculture practice in cold climates, refining freeze tolerance developments of plants, prolonging the harvest season in cold climates, and improvement in cryosurgery procedures will boost the industry sales. Additionally, the rising usage of antifreeze proteins in yogurts and ice creams is also propelling the market growth during the coming years. Increasing investments by key players to launch new frozen products in the food sector is further expected to boost industry sales. However, limited applications of antifreeze proteins in the food industry and the high associated costs may hamper the market.

The growing application of antifreeze proteins in the pharmaceutical sector coupled with rising R&D activities further offers significant growth opportunities to the antifreeze protein market during the forecast period. Along with food applications, antifreeze protein is also used to enrich the bioavailability of drugs due to various bioactive effects such as antimicrobial action, and physiological effects that can underwrite general human health.

Form Insights

The global market is categorized based on form, into solid and liquid. The solid form segment contributed the highest revenue share of more than 95.0% in the global market in 2021, owing to the ease of availability in solid form from the source of origin. They are widely used in the food sector, such as frozen foods, ice cream products, frozen fish, and meats. Furthermore, the solid form has a more extended shelf life than the liquid form, making it more useful in frozen food applications.

On the other hand, the liquid form segment is projected to show significant growth during the forecast period, owing to its increasing demand in the food and pharmaceutical sector. The segment is projected to expand at a CAGR of 26.4% during the forecast period. Liquid form proteins have been researched and developed for applications in vaccines in medicine manufacturing. Moreover, the significant scope of application of liquid antifreeze protein in the pharmaceutical sector is further projected to create significant opportunities for the market. 

Type Insights

The Type I segment contributed a revenue share of more than 65.0% in the global market for antifreeze protein in 2021, as they are extracted on a larger scale from fish. Furthermore, the DNA sequence of Type I antifreeze proteins is easily identified for research and is available in huge quantities. All these factors are expected to drive the growth of this segment.

 Global antifreeze protein market share, by type, 2021 (%)

Moreover, the Type III segment is estimated to show lucrative growth in the market during the coming years, owing to its rising usage in medicine manufacturing. The market is projected to exhibit a CAGR of 27.5% during the forecast period. In addition, the segment held the second-largest revenue share of more than 15.0% in 2021. Type III has better cryopreservation than any other type of antifreeze protein.

Additionally, the antifreeze glycoprotein segment is projected to advance at a significant rate of 27.1% during the forecast period. The rising trend toward glycoprotein food products for various health benefits is further projected to propel market growth. Moreover, the introduction of different organic-based food and cosmetic products by companies is expected to increase the demand further, during the forecast period. 

End-use Insights

Based on end-use, the antifreeze proteins market is categorized into medical, food, cosmetics, and others. The medical end-use segment contributed the highest revenue share of more than 75.0% in the global market in 2021. This is credited to the rising R&D from biotechnology and pharmaceutical companies and enduring global research for COVID-19 vaccinations.

The cosmetics segment is also expected to demonstrate respectable enlargement in the market during the forecast period, owing to the growing usage of antifreeze proteins. The market is projected to expand at a CAGR of 27.5% during the forecast period. In addition, the rising use of antifreeze proteins in the cosmetic sector in Asian and European countries is likely to drive further expansion of this segment in the coming years.

Source Insights

Based on the source, the global market is segregated into fish and others. The fish source segment contributed the highest revenue share of more than 95.0% in the global market in 2021. Easy availability and simplicity of extraction process of antifreeze proteins from fish are the factors driving the growth of this segment within the market.

The others segment is also expected to show a significant growth rate of 25.1% during the forecast period. This segment includes fungi, bacteria, plants, and insects. The insect source has more effective proteins than the fish source due to the extraordinary earthly winter temperatures. Hence, the others segment is expected to witness significant growth.

Regional Insights

Asia Pacific made the largest contribution to the global antifreeze protein market with more than 35.0% revenue share in 2021. This can be credited to the majority of marine capture and aquaculture production being done across the region. Growing demand from the medicine and cosmetic industry, for antifreeze proteins, is driving the industry growth. The presence of world-leading vaccine manufacturers in this region is further adding to the market growth since antifreeze proteins have a wide application in vaccine manufacturing. The emerging trend in China to consume sashimi-smoked products is propelling the market growth.

North America is expected to witness the highest CAGR of 28.5% from 2022 to 2028. This can be credited to the growing demand from the food and cosmetic industry in this region. Furthermore, there has been significant growth in the development and production of antifreeze proteins in this region. Moreover, the fishery department of the U.S. expanded the preservation capacity of the salmon fish catchers and provides the funding. This kind of initiative is expected to boost market growth.

Key Companies & Market Share Insights

Key players are focusing on R&D and exploring commercial applications in food and medicine to meet the increasing demand for frozen foods and vaccines. However, implementing advance-manufacturing techniques has its unique challenges and limitations. Multiple companies are targeting the expansion and launch of premium salmon salad products in the market. In January 2020, Lerøy Seafood Group and DNV GL signed a contract to develop the product certification for STP 86 Salmo Salar. The STP-86 consists of a higher content of omega-3 acids. Some of the prominent companies in the global antifreeze protein market include:

  • Unilever

  • Kaneka Corporation

  • Nichirei Corporation.

  • A/F Protein Inc.

  • Sirona Biochem

  • ProtoKinetix, Inc.

  • Shanghai Yu Tao Industrial Co., Ltd.

  • Kodera Herb Garden Co., Ltd

  • Beijing Huacheng Jinke Technology Co., Ltd.

Antifreeze Protein Market Report Scope

Report Attribute


Market size value in 2022

USD 7.7 million

Revenue forecast in 2028

USD 34.9 million

Growth rate

CAGR of 27.5% from 2022 to 2028

Base year for estimation


Historical data

2017 - 2020

Forecast period

2022 - 2028

Quantitative units

Revenue in USD million and CAGR from 2022 to 2028

Report coverage

Revenue forecast, company ranking, competitive landscape, growth factors, trends

Segments covered

Form, type, end-use, source, region

Regional scope

North America, Europe, Asia Pacific, Central & South America, Middle East & Africa

Country scope

U.S., Norway, Spain, Denmark, China, Japan, Morocco, Peru

Key companies profiled

Unilever, Kaneka Corporation, Nichirei Corporation, A/F Protein Inc., Sirona Biochem, ProtoKinetix, Inc., Shanghai Yu Tao Industrial Co., Ltd., Kodera Herb Garden Co., Ltd, Beijing Huacheng Jinke Technology Co., Ltd.

Customization scope

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Segments Covered in the Report

This report forecasts revenue growth at global, regional & country levels and provides an analysis of the latest industry trends and opportunities in each of the sub-segments from 2017 to 2028. For this study, Grand View Research has segmented the global antifreeze protein market report based on the form, type, end-use, source, and region:

  • Form Outlook (Revenue, USD Million, 2017 - 2028)

    • Solid

    • Liquid

  • Type Outlook (Revenue, USD Million, 2017 - 2028)

    • Type I

    • Type III

    • Antifreeze Glycoprotein

    • Others

  • End-use Outlook (Revenue, USD Million, 2017 - 2028)

    • Medical

    • Food

    • Cosmetics

    • Others

  • Source Outlook (Revenue, USD Million, 2017 - 2028)

    • Fish

    • Others

  • Regional Outlook (Revenue, USD Million, 2017 - 2028)

    • North America

      • U.S.

    • Europe

      • Norway

      • Spain

      • Denmark

    • Asia Pacific

      • China

      • Japan

    • Central & South America

      • Peru

    • Middle East & Africa

      • Morocco

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