GVR Report cover Digestive Enzyme Supplements Market Size, Share & Trends Report

Digestive Enzyme Supplements Market Size, Share & Trends Analysis Report By Origin (Animal, Plant, Microbial), By Application, By Region, And Segment Forecasts, 2018 - 2025

  • Report ID: GVR-1-68038-758-2
  • Number of Pages: 110
  • Format: Electronic (PDF)

Report Overview

The global digestive enzyme supplements market size to be valued at USD 1.6 billion by 2025. Surging demand for dietary supplements among consumers in light of health concerns and awareness towards nutraceuticals is anticipated to aid in market expansion over the forecast period. Various factors, such as changing lifestyles, hectic work schedules, and overtime at workplaces, are leading consumers towards packaged food, which often results in digestive problems. Digestive enzymes help in breaking down food into nutrient form for the body to absorb them. Growing requirement for these products in light of health benefits is anticipated aid in market expansion over the next nine years.

Digestive Enzyme Supplements Market size, by origin

The key driver for the industry includes positive viewpoint towards sports nutrition and growing concerns regarding stomach health. Increasing number of global sports event including the Big Bash League, English Premier League, NBA, and Indian Primer League have forced athletes to focus on maintaining their physical strength, which is expected to stimulate growth over the upcoming years.

Growing requirement of digestive enzymes as they help in treating pancreatic and gastrointestinal diseases is projected to fuel its demand. Moreover, increasing prevalence of intestinal diseases along with pancreatic surgery will propel growth over the upcoming years. Moreover, the easy availability of over-the-counter drugs is likely to augment industry growth over the next nine years.

The ban on animal killings in several countries including the U.S., Canada, Australia, and the UK is expected to affect the availability of the animal-based products adversely. In addition, high usage of products made up of prebiotics and probiotics is expected to restrict the demand for digestive enzyme supplements over the next nine years.

Increasing consumer awareness regarding the adverse impact of inorganic food on human health has shifted industry trend towards promoting organic food market. Furthermore, increasing consumption of organic foods on account of providing nutritional benefits is projected to refrain consumers from preferring dietary supplements in the form of capsules and tablets.

Digestive Enzyme Supplements Market Trends

The market is expected to grow owing to the factors such as the rising prevalence of gastrointestinal problems, growing elderly population, increased awareness about good health, and a focus on preventive health management. Natural digestive enzyme production declines with age, resulting in reduced food consumption, slower digestion, stomach pain, and a variety of other GI (gastrointestinal)ailments. As a result, the digestive enzyme supplements market is expected to grow steadily during the forecast period.

Digestive supplements comprising vitamins C and D and micronutrients are a safe, low-cost alternative to aid the immune system in combating COVID-19 and other severe respiratory tract illnesses. As a result, there has been an upsurge in the demand for digestive supplements since the start of pandemic. Moreover, increased public health awareness due to the spread of infection is expected to aid the market growth of digestive supplements in the forecast period.

The barriers to expansion include the availability of alternatives for the supplements of digestive enzyme and also the preference for probiotics and prebiotics over digestive enzymes. Furthermore, restrictions against animal killing imposed in countries such as the United States, Australia, Canada, and the United Kingdom, and various NGOs raising concerns about animal-derived digestive enzyme supplements, are expected to have a negative impact on animal-based products, which is hampering the market growth.

The COVID-19 outbreak has raised public awareness about the importance of staying fit. Owing to this many people are shifting their preferences towards digestive enzyme supplements. Furthermore, the increased use of digestive enzyme supplements by athletes and sportspeople is expected to provide significant growth opportunities for the market.

Origin Insights

Animal-derived enzymes dominated the industry and accounted for 45% of the global revenue share in 2015. These products are anticipated to witness less growth as compared to other enzyme supplements as they are functional only at high pH levels and are less efficient for aiding digestion in the stomach.

Animal-derived products, for instance, pancreatic, proteases, and amylases are functional for enhancing conditions including exocrine pancreatic insufficiency, pancreatitis, and pancreatic cancer. However, the product is likely to face challenges, as vegetarians do not prefer these products. In addition, factors such as consumer’s sensitiveness and allergies to these products are anticipated to hinder growth over the forecast period.

Microbial enzymes are fermented microbes and are derived from microorganism including fungi and bacteria including Aspergillus oryzae and Aspergillus niger. Fermented microbes exhibit broad ranges of pH, temperature, and substrate specificities. In addition, the abundant availability of a wide range of enzymatic activities along with low production cost as compared to animal enzymes will fuel its demand over the next nine years.

Application Insights

Additional supplements were the largest segment, valued at USD 602.2 million in 2015. Rising awareness towards weight loss and maintaining a healthy lifestyle among adults & old-age people is projected to have a positive impact on the digestive enzyme supplements market. Furthermore, increasing expenditure for the development of new supplements is anticipated to augment demand over the forecast period.

Digestive Enzyme Supplements Market share, by application

The application of digestive enzymes in sports nutrition is expected to gain importance owing to increasing consumption of these products by athletes, sportsmen, bodybuilders, and patients as a dietary ingredient. Furthermore, increasing number of fitness centers, gymnasiums, and health clubs coupled with growing health consciousness is likely to propel the growth.

Regional Insights

North America was the largest market with 46.3% volume share in 2015 and is expected to remain the market leader on account of increasing usage along with reduced calorie level and high nutritional content. Increasing awareness of nutritional products in Mexico on account of new product launches is anticipated to promote the application of supplements over the forecast period.

Digestive Enzyme Supplements Market Trends by Region

Increasing demand for sports nutrition products among working professionals in the U.S. for maintaining muscular strength is anticipated to promote the usage of digestive enzyme supplements. Furthermore, new product developments and attractive internet campaigns by companies, such as Amway and Herbalife in the U.S., are projected to amplify the demand over the upcoming years.

Asia Pacific is expected to witness the fastest growth over the upcoming years on account of poor dietary habits of the population in countries including India, China, and Japan. In addition, rising expenditure on health enhancing ingredients in light of physical fitness requirements and increasing sports activities in the region is likely to fuel demand over the forecast period.

Key Companies & Market Share Insights

The industry is highly competitive in nature owing to low product differentiation in the market. Large numbers of market players are present in the U.S. and Canada. Major market participants include Klaire Labs, National Enzyme Company, ProteoZymes, Metagenics, Douglas Labs, Integrative Therapeutics, and Amway.

In October 2015, XYMOGEN’s production site received approval from Therapeutic Goods Administration (TGA), a pharmaceutical regulatory agency located in Australia. In October 2015, XYMOGEN’s production site received approval from Therapeutic Goods Administration (TGA), a pharmaceutical regulatory agency based in Australia, and became the exclusive manufacturer of supplements in the U.S. This strategy was implemented to gain market penetration for digestive enzyme supplements in Australia.

Recent Developments

  • In June, 2022, the kiwi regularity chewable was introduced by Enzymedica, a Florida-based firm that provides high-quality natural digestive solutions.  Zespri kiwis are notable for having a higher level of UV light exposure that causes the plants to produce more advantageous secondary metabolites like polyphenols and carotenoids as a result of their location.

  • Vox Nutrition announced the addition of six vitamin supplements to the extensive supplement collection. Each of the supplements has experienced significant growth in recent years and has shown to be in great demand and essential for any nutrition business

  • DuPont Nutrition & Biosciences (DuPont) has launched BonlactaTM, latest enzyme for the lactose-free dairy industry, in North America. This unique product enables the cost reduction and process optimization, allowing the manufacturing of a wide variety of lactose-free dairy products across North America at competitive prices

Digestive Enzyme Supplements Market Report Scope

Report Attribute


Revenue forecast in 2025

USD 1.6 billion

Base year for estimation


Historical data

2014 - 2015

Forecast period

2016 - 2025

Quantitative units

Revenue in USD billion/million and CAGR from 2016 to 2025

Report coverage

Revenue forecast, company ranking, competitive landscape, growth factors, and trends

Segments covered

Origin, application, region

Regional scope

North America; Europe; Asia Pacific; Central & South; America & MEA

Country scope

U.S.; Germany; France; UK; China; Japan; Brazil; South Africa

Key companies profiled

Klaire Labs; National Enzyme Company; ProteoZymes; Metagenics; Douglas Labs; Integrative Therapeutics; Amway.

Customization scope

Free report customization (equivalent to up to 8 analysts working days) with purchase. Addition or alteration to country, regional & segment scope.

Pricing and purchase options

Avail customized purchase options to meet your exact research needs. Explore purchase options


Global Digestive Enzyme Supplements Market Segmentation

This report forecasts volume & revenue growth at global, regional & country level and provides an analysis on the industry trends in each of the sub-segments from 2014 to 2025. For the purpose of this study, Grand View Research has segmented the global digestive enzyme supplements market on the basis of origin, application, and region:

Global Digestive Enzyme Supplements Market Segmentation

  • Origin Outlook (Volume, Tons; Revenue, USD Million; 2014 - 2025)

    • Animal

    • Plant

    • Microbial

    • Others

  • Application Outlook (Volume, Tons; Revenue, USD Million; 2014 - 2025)

    • Additional supplements

    • Medical & infant nutrition

    • Sports nutrition

  • Regional Outlook (Volume, Tons; Revenue, USD Million; 2014 - 2025)

    • North America

      • The U.S.

    • Europe

      • Germany

      • France

      • UK

    • Asia Pacific

      • China

      • Japan

    • Central & South America

      • Brazil

    • MEA

      • South Africa

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