Extracorporeal Membrane Oxygenation (ECMO) Machine Market Size, Share & Trends Analysis Report By Component (Cannula, Controllers), By Modality (VA, VV, AV), By Application (Respiratory, Cardiac, ECPR), And Segment Forecasts, 2019 - 2026

Industry Insights

The global extracorporeal membrane oxygenation machine market size was valued at USD 267.60 million in 2018 and is projected to expand at a CAGR of 4.4% over the forecast period. Rising incidences of Chronic Obstructive Pulmonary Disorder (COPD), cardiopulmonary diseases, and respiratory failures are the key factors driving the market. Major applications of ECMO machines include management of cardiopulmonary failure or cardiogenic shock, and respiratory failure.

This treatment option can also be recommended for patients undergoing a heart or lung transplant surgery. According to American Journal of Respiratory and Critical Care Medicine (2016), in U.S., nearly 6.5% of the adult population was diagnosed with COPD and it was estimated to be the third leading cause of death in the country.

In addition, according to European Respiratory Journal, nearly 50 to 90% of the COPD burden is undiagnosed. Thus, growing demand for effective critical care is expected to boost the product demand during the forecast period. After the incorporation of ECMO machines in the treatment and management of the swine flu epidemic of 2009, the number of ECMO centers have increased significantly.

Moreover, increasing tobacco consumption and resulting lifestyle disorders are expected to boost the demand for emergency care. The ECMO machines are gaining popularity in the hospital and healthcare systems due to increasing application in the treatment of respiratory disorders. These machines are also used in cardiac failure cases to facilitate auxiliary oxygen support system and in neonates and pediatric patients.

Component Insights

On the basis of component, the ECMO machine market is segmented into pumps, oxygenators, controllers, cannula, and accessories. The oxygenators segment is expected to dominate the market owing to the factors, such as increasing incidence of severe lung diseases and growing awareness about applications of ECMO machine. For instance, according to Canadian Lung Association, in 2017, around 28,600 people in Canada were diagnosed with cancer.

In addition, according to the America Lung Association, more than 11 million people get diagnosed with COPD in U.S. each year. According to the World Health Organization (WHO), over 3 million people in Japan suffered from asthma in 2015, among which, 7% were severe cases while 30% had moderate asthma. There were about 403,000 deaths resulting from respiratory diseases in Europe in 2012, which was equal to 8% of overall deaths in the same year, as per the statistics of Eurostat.

Application Insights

On the basis of application, the market is segmented into Extracorporeal Cardiopulmonary Resuscitation (ECPR), respiratory, and cardiac. Each of these segments are further segmented as per application in neonates, pediatric, and adult care. The respiratory segment led the ECMO machines market in 2018 and accounting for over 44% of the global share. This can be attributed to utilization of ECMOs as artificial lungs, thus playing a crucial role in supporting pulmonary function.

In addition, according to a 2016 report published by the Extracorporeal Life Support Organization, globally, nearly 45,035 patients suffer from respiratory illnesses and require extracorporeal membrane oxygenation therapy. The adult ECMO segment held the largest share in 2018 and is estimated to witness a lucrative growth over the forecast period. This can be attributed to the increased prevalence of COPD and associated cardiopulmonary diseases in adult population. The ECMO systems are used to treat severe cardiac conditions, such as cardiac shock or arrest, wherein the ECMO machines serve as an artificial heart.

According to the report published by the Extracorporeal Life Support Organization, in 2016, approximately 22,140 patients suffered from cardiac illness worldwide and required ECMO.

Extracorporeal cardiopulmonary resuscitation is also known as rescue therapy. It is used to treat patients suffering from in-hospital and out-of-hospital cardiac arrest. According to the report published by the Extracorporeal Life Support Organization, in 2016, nearly 6,421 people globally required ECPR. ECMO is recommended as a treatment option for neonates who are unresponsive towards high frequency ventilation.

The veno-arterial ECMO machine is used in most cases due to a greater survival rate as compared to veno-venous ECMO. Increasing demand for the ECMO systems is majorly attributed to rising cases of chronic respiratory conditions like COPD, emphysema, and chronic bronchitis along with growing awareness about health disorders. As per the U.S. National Center for Health Statistics, in 2014, more than 8.7 million individuals suffered from chronic bronchitis and 3.4 million individuals suffered from emphysema.

Modality Insights

Based on modality, the market is segmented into arterio-venous, veno-arterial and veno-venous. These modalities are used to provide hemodynamic support and to facilitate gaseous exchange in patients with cardiac or respiratory failure. Both gas exchange and hemodynamic supports are provided by the veno-arterial ECMO system. It majorly works by circulating the blood flow from the patients’ heart and lungs to the ECMO circuit. The veno-venous system on the other hand provides sole gas exchange support in which, the blood is circulated to the heart prior to pulmonary circulation.

According to the U.S. National Institute of Health (NIH), combination of veno-venous and veno-arterial is used in specific cases, such as cardiogenic shock. The veno-arterial segment led the market in 2018 and is anticipated to expand at the maximum CAGR of 4.9% over the forecast period due to wide scope of application in the treatment of cardiovascular collapse. Veno-arterial systems can be used for the treatment/management of decreased cardiac output and tissue hypoperfusion, which results in cardiogenic shock. This can act as a trigger for myocardial infraction or chronic ischemia.

Regional Insights

North America held the largest market share in 2018 owing to the well-developed primary, secondary, and tertiary care hospitals, reimbursement framework, favorable government funding, and higher awareness about the ECMO systems facilitating their adoption in hospitals. Asia Pacific is expected to be the fastest-growing regional market over the forecast period. This can be attributed to increasing prevalence of lung cancer in countries, such as China and India. According to National Cancer Center (NCC), each year 781,000 patients are diagnosed with lung cancer in China and is one of the leading causes of cancer deaths in the country.

Extracorporeal Membrane Oxygenation Machine Market Share Insights

Prominent companies in the global market include MAQUET Holding B. V. & Co. KG, Microport Scientific Corporation, Medos Medizintechnik AG, Sorin Group, Medtronic, Plc., Terumo Cardiovascular Systems Corporation, and Nipro Medical Corporation. New product development and technological advancements in the existing portfolio are the key strategies undertaken by most of these firms.

Refinements in the existing technology were done by Terumo Cardiovascular Systems Corporation during the production of CAPIOX FX Oxygenator. Moreover, Medtronic Plc designed Minimax Plus Oxygen System for patient (neonates and children), with features, such as venous air director and low arterial port, which are integrated in the system to increase the safety levels and performance.

Report Scope

Segments Covered in the Report

This report forecasts revenue and volume growth at global, regional, and country levels and provides an analysis of the latest industry trends in each of the sub-segments from 2015 to 2026. For the purpose of this study, Grand View Research has segmented the global extracorporeal membrane oxygenation machine market report on the basis of component, modality, application, and region:

• Component Outlook (Revenue, USD Million, 2015 - 2026)

  • Pumps

  • Oxygenators

  • Controllers

  • Cannula

  • Accessories

• Modality Outlook (Revenue, USD Million, 2015 - 2026)

  • Veno-Arterial (VA)

  • Veno-Venous (VV)

  • Arterio-Venous (AV)

• Application Outlook (Revenue, USD Million, 2015 - 2026)

  • Respiratory

    • Neonates

    • Pediatric

    • Adults

  • Cardiac

    • Neonates

    • Pediatric

    • Adults

  • Extracorporeal Cardiopulmonary Resuscitation (ECPR)

    • Neonates

    • Pediatric

    • Adults

• Regional Outlook (Revenue, USD Million, 2015 - 2026)

  • North America

    • U.S.

    • Canada

  • Europe

    • Germany

    • U.K.

    • France

    • Italy

    • Spain

  • Asia Pacific

    • China

    • Japan

    • India

    • Thailand

    • South Korea

  • Latin America

    • Brazil

    • Mexico

    • Argentina

    • Colombia

  • Middle East and Africa (MEA)

    • South Africa

    • Saudi Arabia

    • UAE