Molecular Cytogenetics Market Report

Molecular Cytogenetics Market Analysis Report By Application (Oncology, Personalized Medicine), By Product, By End Use, By Technology (FISH, Immunochemistry, Karyotyping), And Segment Forecasts, 2018 - 2025

  • Published Date: Feb, 2018
  • Base Year for Estimate: 2016
  • Report ID: GVR-1-68038-023-1
  • Format: Electronic (PDF)
  • Historical Data: 2014 - 2016
  • Number of Pages: 236

Industry Insights

The global molecular cytogenetics market size was estimated at USD 1.5 billion in 2016. Cytogenetic analysis was earlier limited to investigation of cellular aspects that covered detection of genomic aberrations and study of chromosomal structure in heredity conditions. In the current scenario, cytogenetic analysis goes beyond simple investigation of chromosomal status of genome. This has accelerated the study of chromosomal changes that are involved in disease pathogenesis, three-dimensional organization of the human genome, and nature of inherited syndromes. 

Japan molecular cytogenetics market

Currently, the most important goal of human genetics is to bridge the gap between clinical applications of genetic findings and accordingly provide a refined medical service. Growth in utilization of genetic information in predictive models for disease traits has a direct impact on adoption of cytogenetic tools, thereby boosting revenue generation.

Increasing incidence of cancer and related growth in mortality per year has significantly driven the market. Continued rise in new cancer cases has emphasized the need for development of advanced technologies for a comprehensive understanding of cancer at a genomic level.

FISH and Comparative Genomic Hybridization (CGH) are among the most recognized cytogenetic techniques as they provide thorough information about cancer-related molecular signatures. These methods aid in gaining insights on cancer progression.

Growing activities in pharmacogenomics are anticipated to significantly impact market growth as several cytogenetic tools have been successfully used for pharmacogenomic biomarker studies. Effective use of CGH, FISH, and sequencing technology in pharmacogenomics is evident by the presence of a substantial number of published articles demonstrating the role of cytogenetic techniques in pharmacogenomic testing.

Ongoing technological advancements in CGH and FISH, with respect to resolution and specificity, have augmented the application scope of cytogenetics tools in basic research and molecular diagnostics. These advancements have successfully overcome the limitations of conventional cytogenetic analysis.

Lack of predictable coverage and reimbursement policies for new genomic tools could hinder the application of molecular cytogenetics in cancer and personalized care. Moreover, dearth of skilled personnel and high expense associated with maintenance and handling of advanced techniques are expected to impede the market in future.

Application Insights

A thorough understanding of genomes is fundamental to achieving several objectives of cancer management: therapeutic strategies, fast and precise diagnosis, survival prediction, and recurrence risk estimation. Effective and high usage of molecular cytogenetic techniques for in-depth cancer studies has enabled oncology to emerge as the largest application segment.

Pharmacotherapies and personalized treatment options are recognized as the two most important strategies for achieving improved treatment outcomes. With a shift toward personalized medicine, the use of molecular cytogenetic techniques is expected to grow lucratively throughout the forecast period. This is mainly because molecular cytogenetic analysis has proven to be vital in personalized medicine through its wide applications in cytoproteomics, cytogenomics, drug discovery and development, and biomarker discovery.

Product Insights

The molecular cytogenetics market offers a broad range of products, such as instruments/equipment, consumables, and software and services. Advances in molecular biology techniques have also propelled the development of associated consumables, reagents, kits, and software.

Rising usage of media and reagents while performing cytogenetic analysis has rendered consumables as the largest segment. Consumables assist in gaining accurate and reproducible results in standard as well as advanced clinical cytogenetic protocols.

However, in the coming years, software and services are expected to serve as a lucrative source of revenue owing to ongoing development in solutions and algorithms to manage and interpret massive amounts of genomic data.

Ongoing genomic research activities have resulted in surplus volumes of genomic findings. This, in turn, has propelled companies to invest in the development of robust and sophisticated software and algorithms to simplify cytogenetic analysis.

End-use Insights

Clinical and research laboratories dominated the market in 2016. This is majorly due to growing implementation of cytogenetic techniques in clinical diagnosis. Ongoing research pertaining to pathways underlying various chromosomal diseases has enabled this segment to attain the largest share.

With growing demand for targeted therapies, the implementation of molecular cytogenetics in pharmaceutical and biotech companies is expected to grow at a lucrative pace. The popular trend of companion diagnostics is also expected to support the growth of this segment throughout the forecast period.

Technology Insights

Availability, turnaround time, cost, and specificity are key factors that play a significant role in the adoption of cytogenetic techniques. In the current scenario, CGH and FISH techniques are widely adopted across various applications such as diagnostics, research activities, and medicine development.

Global molecular cytogenetics market

The many advantages CGH and FISH techniques offer over conventional techniques have allowed these segments to account for a major share in the market. CGH captured the dominant share owing to its vital role in comprehensive cancer studies. High resolution offered by array-based CGH has also contributed to its growth. Array-based CGH has significantly addressed the limitations of standard CGH with respect to labor requirement and resolution. This technique has also eliminated the need for metaphase chromosomes, which results in enhanced resolution.

Regional Insights

North America accounted for the largest share in 2016 mainly due to the local presence of major entities, such as Agilent Technologies, Inc. Moreover, presence of effective regulatory framework for the regulation of genetic tests has significantly propelled the regional market.

Asia Pacific is expected to emerge as the fastest growing regional market during the course of the forecast period. Continuous GDP growth of countries such as China and India is anticipated to enhance consumer buying power and drive regional growth. Ongoing workshops and interventions in Asia Pacific pertaining to current trends and developments in human genetics and disease management are driving the Asian market. These workshops are aimed at improving awareness about the significance of advanced diagnostics and therapies among the population.

Molecular Cytogenetics Market Share Insights

BIOVIEW; Danaher; MetaSystems; Agilent Technologies, Inc.; Abbott; Bio-Rad Laboratories, Inc.; Illumina, Inc.; Oxford Gene Technology; F. Hoffmann-La Roche Ltd.; PerkinElmer Inc.; Quest Diagnostics Incorporated; Applied Spectral Imaging; Biological Industries USA, Inc.; CytoTest; Cytognomix; Genial Genetics; and Diagnostic Cytogenetics, Inc. (DCI) are some of the prominent players operating in the market. These players are engaged in manufacturing and marketing of cytogenetic tests and techniques for service providers.

Understanding the growing demand for cytogenetic analysis amongst the population, manufacturers are making significant investments to broaden their product portfolio. They are also engaging in mutually beneficial partnerships with laboratories and research institutes, which in turn, boosts revenue generation for these companies.

Some service providers that offer cytogenetic technique-based services are Weill Cornell Medicine; UCLA Health - UCLA Pathology and Laboratory Medicines; OHSU School of Medicine-Molecular and Medical Genetics; Integrated Systems Engineering S.r.l.; WiCell Research Institute, Inc.; Virtual Scientific; UW Cytogenetic Services; Genesis Laboratories Inc.; Calgary Laboratory Services; Neogenomics; ARUP Laboratories; and South West Thames Regional Genetics Service.

Report Scope

Attribute

Details

Base year for estimation

2016

Actual estimates/Historical data

2014 - 2016

Forecast period

2017 - 2025

Market representation

Revenue in USD Million and CAGR from 2017 to 2025

Regional scope

North America, Europe, Asia Pacific, Latin America, Middle East & Africa

Country scope

U.S., Canada, Germany, U.K., China, Japan, Brazil, South Africa

Report coverage

Revenue forecast, company share, competitive landscape, growth factors and trends

15% free customization scope (equivalent to 5-analyst working days)

If you need specific market information, which is not currently within the scope of the report, we will provide it to you as a part of customization


Segments Covered in the Report

This report forecasts revenue growth at global, regional, and country levels and provides an analysis on latest industry trends in each of the sub-segments from 2014 to 2025. For the purpose of this study, Grand View Research has segmented the global molecular cytogenetics market report on the basis of application, product, end use, technology, and region:

  • Application Outlook (Revenue, USD Million, 2014 - 2025)

    • Genetic Disorders

    • Oncology

    • Personalized Medicine

    • Other Applications

  • Product Outlook (Revenue, USD Million, 2014 - 2025)

    • Instruments

    • Consumables

    • Software & Services

  • End-use Outlook (Revenue, USD Million, 2014 - 2025)

    • Clinical & Research Laboratories

    • Hospitals & Pathology Laboratories

    • Academic Research Institutes

    • Pharmaceutical and Biotechnology Companies

    • Other End-use

  • Technology Outlook (Revenue, USD Million, 2014 - 2025)

    • Comparative Genomic Hybridization

      • Array-based comparative genomic hybridization

      • Standard comparative genomic hybridization

    • Fluorescence In Situ Hybridization (FISH)

    • Immunohistochemistry

    • Karyotyping

      • Spectral karyotyping

      • Virtual karyotyping

    • Other Techniques

  • Regional Outlook (Revenue, USD Million, 2014 - 2025)

    • North America

      • U.S.

      • Canada

    • Europe

      • Germany

      • U.K.

    • Asia Pacific

      • Japan

      • China

    • Latin America

      • Brazil

    • Middle East & Africa

      • South Africa

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