Scaffold technology facilitates thousands of surgical procedures that are performed to repair diseased tissues or organs by providing support to surgically inserted implants. Study of mammalian cell biology relies on cellular models to examine specific biological mechanisms under different test conditions. Characteristic properties of such models play a crucial role in influencing their performance in research studies. Scaffolds are employed in these cellular models to offer mechanical stability, biocompatibility, and biodegradability in providing proper support for cell proliferation and differentiation, which significantly improves their applicability in drug discovery and regenerative treatments.
Different types of scaffolds based on their fabrication material and applications
The characteristics and material properties of the scaffolds enable biological cross talk between these 3D substrates and the microenvironment. Depending upon the material used to fabricate scaffolds, they are segregated into hydrogels, polymeric scaffolds, micropatterned surface microplates, and nanofiber-based scaffolds.
Various applications of scaffolds include the drug development process, cancer biology, stem cell research, tissue engineering & clinical applications, high throughput screening, cell to matrix interactions, cell to cell interactions, cell migration assays, and transfections.
End users of scaffold technology include biotechnology and pharmaceutical organizations, research laboratories and institutes, hospitals and diagnostic centers, and academic institutes.
Addressable scaffold technology market
Steady developments in scaffold technology that facilitate the tissue engineering process for its use in cell cultivation and organoid generation are expected to positively influence the growth of pharmaceutical organizations and biotechnology companies. Moreover, market entities that are engaged in offering products for 3D cell culture and reconstructive procedures are anticipated to experience the positive impact of the emergence of scaffold technology in tissue engineering.
Usage of scaffolds to enable proper cell proliferation in the field of tissue engineering is expected to positively influence the growth of the scaffold technology market.
Several key participants have considered the profitable opportunities in the scaffold technology vertical and hence invested efforts for the development of novel products. Becton, Dickinson and Company; Merck KGaA; 3D Biotek LLC.; Tecan Trading AG.; Thermo Fisher Scientific, Inc.; NuVasive, Inc.; Molecular Matrix Inc.; Acelity; ReproCELL Europe Ltd (Reinnervate); Xanofi; Matricel GmbH; Nanofiber Solutions; Pelo Biotech GmbH; Corning, Inc.; Medtronic; 4titude; 3D Biomatrix; Vericel Corporation; Avacta Life Sciences Limited; Molecular Partners; and Akron Biotech are some of the prominent players in this space.
Growing need for transplantation procedures to drive the demand for scaffolds
Scaffold technology allows researchers to grow tissues and organs in in vitro conditions for patients requiring transplant procedures. Increasing requirement of transplantation procedures due to road injuries, aging, and diseases coupled with the lack of adequate organ donors for transplantation procedures is the major factor to render growth to this vertical.
Ongoing technological advancements in biomaterial science have enabled the development of next generation scaffolds to support 3D culturing of cells and tissue engineering for reconstructive surgical procedures. For instance, the advent of extracellular matrix-based eco-friendly scaffold technology to overcome drawbacks associated with conventional scaffolds, such as low antimicrobial property, fast degradation rate, and low mechanical consistency, is expected to encourage the growth of this market in the coming years.
In-depth report on global scaffold technology market by Grand View Research: