GVR Report cover Biological Skin Substitutes Market Size, Share & Trends Report

Biological Skin Substitutes Market Size, Share & Trends Analysis Report, By Type (Human Donor Tissue-derived Products, Acellular Animal-derived Products), By Application, By End-use, By Region, And Segment Forecasts, 2023 To 2030

  • Report ID: GVR453953
  • Number of Pages: 0
  • Format: Electronic (PDF)

Skin substitutes are a diverse set of biologic, synthetic, or biosynthetic materials that can offer temporary or permanent coverage of open skin lesions. Because of the existence of a basement membrane, biological skin substitutes may enable for the formation of a more natural new dermis and superior re-epithelialization features. 

The prevalence of chronic wounds is rising, as are the number of burn & trauma cases and the attention being paid to technical breakthroughs. Additionally, there is a need for relatively accessible and affordable skin-replacement solutions, which has prompted numerous research teams across the globe to concentrate on developing biomaterials for skin replacement. The modified tissues would be very helpful in human wound healing since they not only shut wounds but also encourage dermal regeneration.

Additionally, the demand for biological tissue engineered skin substitutes is increasing owing to the rising prevalence of acute wounds across the globe. The current trend in burn wound care has changed to a more all-encompassing strategy to enhance quality of life and the long-term form and function of the healed burn wounds. As a result, several biological skin substitutes have had to be developed for the treatment of acute burn injuries as well as post-burn reconstructions. 

Biological tissue engineered skin substitutes are used for the treatment of first degree burn cases. For instance, as per the WHO, over 1,000,000 people are registered, annually, as moderately or severely burnt. Similarly, according to Joye Law Firm, the following are the statistics about burn injuries in the U.S.:

  • On average, there are 450,000 burn injuries in the U.S.

  • Each year, about 3,500 people are fatally injured in a fire or burn accident

  • Approximately 45,000 people are hospitalized each year for burn injuries. Of those who are hospitalized, 25,000 are admitted to specialized burn centers.

    • Of those who suffer a burn injury, 70% are male and 30% are female

    • Of those admitted to a hospital for a burn injury, 44% list the cause as fire/flame, 33% scald, 9% contact, 4% electrical, 3% chemical, and 7% “other”

The major advantage of biological tissue engineered skin substitutes is that skin is readily available from the patient itself. Biological tissue engineered skin substitutes have more extracellular matrix, which aids in excellent re-epithelialization and faster healing of the wound.

Moreover, there is an increase in funding from public and commercial organizations for research and development of regenerative therapies, and the acceptance of regenerative medicine is likely to propel the market as a whole. Furthermore, 3D bioprinting technology has evolved as a practical way for fabricating skin replacements from primary cells derived from patients' skin cells. Although this technology is currently in its early stages, it will be refined in the near future.

Importantly, revascularization has emerged as a potential notion in skin tissue engineering. This method tries to generate premade microvascular networks inside skin substitutes before to transplantation and has a particular benefit in treating chronic wounds. To conclude, these different approaches of developing novel skin substitutes, such as the utilization of stem cells, revascularization, and 3D bioprinting, provide renewed optimism.

Biological Skin Substitutes Market Segmentation

  • By Type

    • Human Donor Tissue-derived Products

    • Acellular Animal-derived Products

    • Biosynthetic Products

  • By Application

    • Acute Wounds

      • Surgery & Trauma

      • Burn Injuries

    • Chronic Wounds

      • Diabetic Foot Ulcers

      • Pressure Ulcers

      • Venous Leg Ulcers

      • Other Chronic Wounds

  • By End-use

    • Hospitals

    • Wound Care Centers

    • Home Healthcare

    • Others

Key Players

  • Organogenesis, Inc.

  • 3M

  • Integra LifeSciences Corporation

  • Smith and Nephew

  • Stratatech Corporation

  • Tissue Regenix

  • Mimedx

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