Downstream Processing Market Size, Share & Trends Report

Downstream Processing Market Size, Share & Trends Analysis Report By Product (Chromatography Systems, Filters), By Technique (Purification, Formulation), By Application, By Region, And Segment Forecasts, 2023 - 2030

  • Report ID: GVR-2-68038-495-6
  • Number of Report Pages: 115
  • Format: PDF, Horizon Databook
  • Historical Range: 2018 - 2021
  • Forecast Period: 2023 - 2030 
  • Industry: Healthcare

Market Segmentation

  • Downstream Processing Product Outlook (Revenue, USD Billion, 2018 - 2030)
    • Chromatography Systems
    • Filters
    • Evaporators
    • Centrifuges
    • Dryers
    • Others
  • Downstream Processing Technique Outlook (Revenue, USD Billion, 2018 - 2030)
    • Cell Disruption
    • Solid-liquid separation
      • Filtration
      • Centrifugation
    • Concentration
      • Evaporation
      • Membrane filtration
    • Purification by Chromatography
    • Formulation
  • Downstream Processing Application Outlook (Revenue, USD Billion, 2018 - 2030)
    • Antibiotic Production
    • Hormone Production
    • Antibodies Production
    • Enzyme Production
    • Vaccine Production
  • Downstream Processing Regional Outlook (Revenue, USD Billion, 2018 - 2030)
    • North America
      • North America Downstream Processing Market, By Product
        • Chromatography Systems
        • Filters
        • Evaporators
        • Centrifuges
        • Dryers
        • Others
      • North America Downstream Processing Market, By Technique
        • Cell Disruption
        • Solid-liquid separation
          • Filtration
          • Centrifugation
        • Concentration
          • Evaporation
          • Membrane filtration
        • Purification by Chromatography
        • Formulation
      • North America Downstream Processing Market, By Application
        • Antibiotic Production
        • Hormone Production
        • Antibodies Production
        • Enzyme Production
        • Vaccine Production
      • U.S.
        • U.S. Downstream Processing Market, By Product
          • Chromatography Systems
          • Filters
          • Evaporators
          • Centrifuges
          • Dryers
          • Others
        • U.S. Downstream Processing Market, By Technique
          • Cell Disruption
          • Solid-liquid separation
            • Filtration
            • Centrifugation
          • Concentration
            • Evaporation
            • Membrane filtration
          • Purification by Chromatography
          • Formulation
        • U.S. Downstream Processing Market, By Application
          • Antibiotic Production
          • Hormone Production
          • Antibodies Production
          • Enzyme Production
          • Vaccine Production
      • Canada
        • Canada Downstream Processing Market, By Product
          • Chromatography Systems
          • Filters
          • Evaporators
          • Centrifuges
          • Dryers
          • Others
        • Canada Downstream Processing Market, By Technique
          • Cell Disruption
          • Solid-liquid separation
            • Filtration
            • Centrifugation
          • Concentration
            • Evaporation
            • Membrane filtration
          • Purification by Chromatography
          • Formulation
        • Canada Downstream Processing Market, By Application
          • Antibiotic Production
          • Hormone Production
          • Antibodies Production
          • Enzyme Production
          • Vaccine Production
    • Europe
      • Europe Downstream Processing Market, By Product
        • Chromatography Systems
        • Filters
        • Evaporators
        • Centrifuges
        • Dryers
        • Others
      • Europe Downstream Processing Market, By Technique
        • Cell Disruption
        • Solid-liquid separation
          • Filtration
          • Centrifugation
        • Concentration
          • Evaporation
          • Membrane filtration
        • Purification by Chromatography
        • Formulation
      • Europe Downstream Processing Market, By Application
        • Antibiotic Production
        • Hormone Production
        • Antibodies Production
        • Enzyme Production
        • Vaccine Production
      • U.K.
        • U.K. Downstream Processing Market, By Product
          • Chromatography Systems
          • Filters
          • Evaporators
          • Centrifuges
          • Dryers
          • Others
        • U.K. Downstream Processing Market, By Technique
          • Cell Disruption
          • Solid-liquid separation
            • Filtration
            • Centrifugation
          • Concentration
            • Evaporation
            • Membrane filtration
          • Purification by Chromatography
          • Formulation
        • U.K. Downstream Processing Market, By Application
          • Antibiotic Production
          • Hormone Production
          • Antibodies Production
          • Enzyme Production
          • Vaccine Production
      • Germany
        • Germany Downstream Processing Market, By Product
          • Chromatography Systems
          • Filters
          • Evaporators
          • Centrifuges
          • Dryers
          • Others
        • Germany Downstream Processing Market, By Technique
          • Cell Disruption
          • Solid-liquid separation
            • Filtration
            • Centrifugation
          • Concentration
            • Evaporation
            • Membrane filtration
          • Purification by Chromatography
          • Formulation
        • Germany Downstream Processing Market, By Application
          • Antibiotic Production
          • Hormone Production
          • Antibodies Production
          • Enzyme Production
          • Vaccine Production
      • France
        • France Downstream Processing Market, By Product
          • Chromatography Systems
          • Filters
          • Evaporators
          • Centrifuges
          • Dryers
          • Others
        • France Downstream Processing Market, By Technique
          • Cell Disruption
          • Solid-liquid separation
            • Filtration
            • Centrifugation
          • Concentration
            • Evaporation
            • Membrane filtration
          • Purification by Chromatography
          • Formulation
        • France Downstream Processing Market, By Application
          • Antibiotic Production
          • Hormone Production
          • Antibodies Production
          • Enzyme Production
          • Vaccine Production
      • Italy
        • Italy Downstream Processing Market, By Product
          • Chromatography Systems
          • Filters
          • Evaporators
          • Centrifuges
          • Dryers
          • Others
        • Italy Downstream Processing Market, By Technique
          • Cell Disruption
          • Solid-liquid separation
            • Filtration
            • Centrifugation
          • Concentration
            • Evaporation
            • Membrane filtration
          • Purification by Chromatography
          • Formulation
        • Italy Downstream Processing Market, By Application
          • Antibiotic Production
          • Hormone Production
          • Antibodies Production
          • Enzyme Production
          • Vaccine Production
      • Spain
        • Spain Downstream Processing Market, By Product
          • Chromatography Systems
          • Filters
          • Evaporators
          • Centrifuges
          • Dryers
          • Others
        • Spain Downstream Processing Market, By Technique
          • Cell Disruption
          • Solid-liquid separation
            • Filtration
            • Centrifugation
          • Concentration
            • Evaporation
            • Membrane filtration
          • Purification by Chromatography
          • Formulation
        • Spain Downstream Processing Market, By Application
          • Antibiotic Production
          • Hormone Production
          • Antibodies Production
          • Enzyme Production
          • Vaccine Production
      • Denmark
        • Denmark Downstream Processing Market, By Product
          • Chromatography Systems
          • Filters
          • Evaporators
          • Centrifuges
          • Dryers
          • Others
        • Denmark Downstream Processing Market, By Technique
          • Cell Disruption
          • Solid-liquid separation
            • Filtration
            • Centrifugation
          • Concentration
            • Evaporation
            • Membrane filtration
          • Purification by Chromatography
          • Formulation
        • Denmark Downstream Processing Market, By Application
          • Antibiotic Production
          • Hormone Production
          • Antibodies Production
          • Enzyme Production
          • Vaccine Production
      • Sweden
        • Sweden Downstream Processing Market, By Product
          • Chromatography Systems
          • Filters
          • Evaporators
          • Centrifuges
          • Dryers
          • Others
        • Sweden Downstream Processing Market, By Technique
          • Cell Disruption
          • Solid-liquid separation
            • Filtration
            • Centrifugation
          • Concentration
            • Evaporation
            • Membrane filtration
          • Purification by Chromatography
          • Formulation
        • Sweden Downstream Processing Market, By Application
          • Antibiotic Production
          • Hormone Production
          • Antibodies Production
          • Enzyme Production
          • Vaccine Production
      • Norway
        • Norway Downstream Processing Market, By Product
          • Chromatography Systems
          • Filters
          • Evaporators
          • Centrifuges
          • Dryers
          • Others
        • Norway Downstream Processing Market, By Technique
          • Cell Disruption
          • Solid-liquid separation
            • Filtration
            • Centrifugation
          • Concentration
            • Evaporation
            • Membrane filtration
          • Purification by Chromatography
          • Formulation
        • Norway Downstream Processing Market, By Application
          • Antibiotic Production
          • Hormone Production
          • Antibodies Production
          • Enzyme Production
          • Vaccine Production
    • Asia Pacific
      • Asia Pacific Downstream Processing Market, By Product
        • Chromatography Systems
        • Filters
        • Evaporators
        • Centrifuges
        • Dryers
        • Others
      • Asia Pacific Downstream Processing Market, By Technique
        • Cell Disruption
        • Solid-liquid separation
          • Filtration
          • Centrifugation
        • Concentration
          • Evaporation
          • Membrane filtration
        • Purification by Chromatography
        • Formulation
      • Asia Pacific Downstream Processing Market, By Application
        • Antibiotic Production
        • Hormone Production
        • Antibodies Production
        • Enzyme Production
        • Vaccine Production
      • Japan
        • Japan Downstream Processing Market, By Product
          • Chromatography Systems
          • Filters
          • Evaporators
          • Centrifuges
          • Dryers
          • Others
        • Japan Downstream Processing Market, By Technique
          • Cell Disruption
          • Solid-liquid separation
            • Filtration
            • Centrifugation
          • Concentration
            • Evaporation
            • Membrane filtration
          • Purification by Chromatography
          • Formulation
        • Japan Downstream Processing Market, By Application
          • Antibiotic Production
          • Hormone Production
          • Antibodies Production
          • Enzyme Production
          • Vaccine Production
      • China
        • China Downstream Processing Market, By Product
          • Chromatography Systems
          • Filters
          • Evaporators
          • Centrifuges
          • Dryers
          • Others
        • China Downstream Processing Market, By Technique
          • Cell Disruption
          • Solid-liquid separation
            • Filtration
            • Centrifugation
          • Concentration
            • Evaporation
            • Membrane filtration
          • Purification by Chromatography
          • Formulation
        • China Downstream Processing Market, By Application
          • Antibiotic Production
          • Hormone Production
          • Antibodies Production
          • Enzyme Production
          • Vaccine Production
      • India
        • India Downstream Processing Market, By Product
          • Chromatography Systems
          • Filters
          • Evaporators
          • Centrifuges
          • Dryers
          • Others
        • India Downstream Processing Market, By Technique
          • Cell Disruption
          • Solid-liquid separation
            • Filtration
            • Centrifugation
          • Concentration
            • Evaporation
            • Membrane filtration
          • Purification by Chromatography
          • Formulation
        • India Downstream Processing Market, By Application
          • Antibiotic Production
          • Hormone Production
          • Antibodies Production
          • Enzyme Production
          • Vaccine Production
      • South Korea
        • South Korea Downstream Processing Market, By Product
          • Chromatography Systems
          • Filters
          • Evaporators
          • Centrifuges
          • Dryers
          • Others
        • South Korea Downstream Processing Market, By Technique
          • Cell Disruption
          • Solid-liquid separation
            • Filtration
            • Centrifugation
          • Concentration
            • Evaporation
            • Membrane filtration
          • Purification by Chromatography
          • Formulation
        • South Korea Downstream Processing Market, By Application
          • Antibiotic Production
          • Hormone Production
          • Antibodies Production
          • Enzyme Production
          • Vaccine Production
      • Thailand
        • Thailand Downstream Processing Market, By Product
          • Chromatography Systems
          • Filters
          • Evaporators
          • Centrifuges
          • Dryers
          • Others
        • Thailand Downstream Processing Market, By Technique
          • Cell Disruption
          • Solid-liquid separation
            • Filtration
            • Centrifugation
          • Concentration
            • Evaporation
            • Membrane filtration
          • Purification by Chromatography
          • Formulation
        • Thailand Downstream Processing Market, By Application
          • Antibiotic Production
          • Hormone Production
          • Antibodies Production
          • Enzyme Production
          • Vaccine Production
      • Australia
        • Australia Downstream Processing Market, By Product
          • Chromatography Systems
          • Filters
          • Evaporators
          • Centrifuges
          • Dryers
          • Others
        • Australia Downstream Processing Market, By Technique
          • Cell Disruption
          • Solid-liquid separation
            • Filtration
            • Centrifugation
          • Concentration
            • Evaporation
            • Membrane filtration
          • Purification by Chromatography
          • Formulation
        • Australia Downstream Processing Market, By Application
          • Antibiotic Production
          • Hormone Production
          • Antibodies Production
          • Enzyme Production
          • Vaccine Production
    • Latin America
      • Latin America Downstream Processing Market, By Product
        • Chromatography Systems
        • Filters
        • Evaporators
        • Centrifuges
        • Dryers
        • Others
      • Latin America Downstream Processing Market, By Technique
        • Cell Disruption
        • Solid-liquid separation
          • Filtration
          • Centrifugation
        • Concentration
          • Evaporation
          • Membrane filtration
        • Purification by Chromatography
        • Formulation
      • Latin America Downstream Processing Market, By Application
        • Antibiotic Production
        • Hormone Production
        • Antibodies Production
        • Enzyme Production
        • Vaccine Production
      • Brazil
        • Brazil Downstream Processing Market, By Product
          • Chromatography Systems
          • Filters
          • Evaporators
          • Centrifuges
          • Dryers
          • Others
        • Brazil Downstream Processing Market, By Technique
          • Cell Disruption
          • Solid-liquid separation
            • Filtration
            • Centrifugation
          • Concentration
            • Evaporation
            • Membrane filtration
          • Purification by Chromatography
          • Formulation
        • Brazil Downstream Processing Market, By Application
          • Antibiotic Production
          • Hormone Production
          • Antibodies Production
          • Enzyme Production
          • Vaccine Production
      • Mexico
        • Mexico Downstream Processing Market, By Product
          • Chromatography Systems
          • Filters
          • Evaporators
          • Centrifuges
          • Dryers
          • Others
        • Mexico Downstream Processing Market, By Technique
          • Cell Disruption
          • Solid-liquid separation
            • Filtration
            • Centrifugation
          • Concentration
            • Evaporation
            • Membrane filtration
          • Purification by Chromatography
          • Formulation
        • Mexico Downstream Processing Market, By Application
          • Antibiotic Production
          • Hormone Production
          • Antibodies Production
          • Enzyme Production
          • Vaccine Production
      • Argentina
        • Argentina Downstream Processing Market, By Product
          • Chromatography Systems
          • Filters
          • Evaporators
          • Centrifuges
          • Dryers
          • Others
        • Argentina Downstream Processing Market, By Technique
          • Cell Disruption
          • Solid-liquid separation
            • Filtration
            • Centrifugation
          • Concentration
            • Evaporation
            • Membrane filtration
          • Purification by Chromatography
          • Formulation
        • Argentina Downstream Processing Market, By Application
          • Antibiotic Production
          • Hormone Production
          • Antibodies Production
          • Enzyme Production
          • Vaccine Production
    • Middle East and Africa (MEA)
      • MEA Downstream Processing Market, By Product
        • Chromatography Systems
        • Filters
        • Evaporators
        • Centrifuges
        • Dryers
        • Others
      • MEA Downstream Processing Market, By Technique
        • Cell Disruption
        • Solid-liquid separation
          • Filtration
          • Centrifugation
        • Concentration
          • Evaporation
          • Membrane filtration
        • Purification by Chromatography
        • Formulation
      • MEA Downstream Processing Market, By Application
        • Antibiotic Production
        • Hormone Production
        • Antibodies Production
        • Enzyme Production
        • Vaccine Production
      • South Africa
        • South Africa Downstream Processing Market, By Product
          • Chromatography Systems
          • Filters
          • Evaporators
          • Centrifuges
          • Dryers
          • Others
        • South Africa Downstream Processing Market, By Technique
          • Cell Disruption
          • Solid-liquid separation
            • Filtration
            • Centrifugation
          • Concentration
            • Evaporation
            • Membrane filtration
          • Purification by Chromatography
          • Formulation
        • South Africa Downstream Processing Market, By Application
          • Antibiotic Production
          • Hormone Production
          • Antibodies Production
          • Enzyme Production
          • Vaccine Production
      • Saudi Arabia
        • Saudi Arabia Downstream Processing Market, By Product
          • Chromatography Systems
          • Filters
          • Evaporators
          • Centrifuges
          • Dryers
          • Others
        • Saudi Arabia Downstream Processing Market, By Technique
          • Cell Disruption
          • Solid-liquid separation
            • Filtration
            • Centrifugation
          • Concentration
            • Evaporation
            • Membrane filtration
          • Purification by Chromatography
          • Formulation
        • Saudi Arabia Downstream Processing Market, By Application
          • Antibiotic Production
          • Hormone Production
          • Antibodies Production
          • Enzyme Production
          • Vaccine Production
      • UAE
        • UAE Downstream Processing Market, By Product
          • Chromatography Systems
          • Filters
          • Evaporators
          • Centrifuges
          • Dryers
          • Others
        • UAE Downstream Processing Market, By Technique
          • Cell Disruption
          • Solid-liquid separation
            • Filtration
            • Centrifugation
          • Concentration
            • Evaporation
            • Membrane filtration
          • Purification by Chromatography
          • Formulation
        • UAE Downstream Processing Market, By Application
          • Antibiotic Production
          • Hormone Production
          • Antibodies Production
          • Enzyme Production
          • Vaccine Production
      • Kuwait
        • Kuwait Downstream Processing Market, By Product
          • Chromatography Systems
          • Filters
          • Evaporators
          • Centrifuges
          • Dryers
          • Others
        • Kuwait Downstream Processing Market, By Technique
          • Cell Disruption
          • Solid-liquid separation
            • Filtration
            • Centrifugation
          • Concentration
            • Evaporation
            • Membrane filtration
          • Purification by Chromatography
          • Formulation
        • Kuwait Downstream Processing Market, By Application
          • Antibiotic Production
          • Hormone Production
          • Antibodies Production
          • Enzyme Production
          • Vaccine Production

Downstream Processing Market Dynamics

Driver: Commercial success of biopharmaceuticals boost demand for innovation in bioprocessing

Many major pharmaceutical companies are shifting their business operations to biopharma industry. This healthy outlook of biopharmaceuticals has resulted into a large number of biopharmaceuticals in pipelines. Several entities are undertaking various initiatives to convert their bioprocessing unit into a single-use unit owing to the increased efficiency of disposables in accelerating the production of biopharmaceuticals. Previously only a handful of firms were able to handle the entire value chain of biologic production. This has dramatically changed in the recent years, as there are several firms in the market, which are involved in the development of biologics. Moreover, the biopharmaceutical industry has itself grown substantially in recent years to include novel product types including nanobodies, rDNA, synthetic vaccines, fusion proteins, soluble receptor, immunoconjugates, and immunotherapeutics.

Biopharmaceuticals is one of the major sectors with respect to growth prospects. Many healthcare entities have estimated that this sector would be one of top 10 revenue generators in the coming years. Moreover, companies are taking efforts for the advancement of this sector to meet increasing demand for bio-based pharmaceuticals, which in turn is expected to lead to an increase in the number of biopharmaceuticals available for clinical use.

Driver: Rising adoption of single-use technology in bioprocessing

The reduction in operating cost and minimization of environmental impact are among the major goals of biopharmaceutical industry. Benefits pertaining to the usage of Single-Use Technology (SUT), such as significant reduction in capital cost and facility construction time, are expected to boost the implementation of this technology. Other advantages include increased scalability, improved mobility, high productivity, eliminated risk of cross-contamination, and reduced demand for cleaning & sterilization. These advantages result in 60% more cost saving than traditional stainless-steel bioprocessing equipment. Single-use buffer preparation systems, sampling/dispensing systems, and filtration systems are some of the key single-use components that have benefitted the downstream process. Purification and separation technologies are gradually adopting single-use upstream processing and vendors are continuously investing to fill the gaps in their offerings. In addition, vendors have begun focusing on developing innovative single-use chromatography solutions. Pre-packed disposable chromatography columns are considered viable solutions to accelerate mAbs and biosimilars-focused clinical trials, particularly where cost control is critical.

Restraint: Dearth of skilled professionals

A shortage of skilled professionals in the field of bio-manufacturing is majorly hindering the growth of downstream processing market. Moreover, the first generation of bio-production staff has begun to retire, which is a major area of concern. Studies suggest that nearly 50% of the CMOs and manufacturers face difficulties in hiring the right bioprocess associates to carry out the production process. To overcome this situation, a number of training programs are offered by the government, academic institutions, and industry participants. A few instances of these include National Institute for Bioprocessing Research & Training (NIBRT) in Ireland; Biomanufacturing Training and Education Center (BTEC), North Carolina State University (U.S.); and Biotech Training Facility in Leiden, the Netherlands. However, training in bioprocess is a relatively slow process and may require on-the-job training even after the technical training. 

What Does This Report Include?

This section will provide insights into the contents included in this downstream processing market report and help gain clarity on the structure of the report to assist readers in navigating smoothly.

Downstream processing market qualitative analysis

  • Industry overview

  • Industry trends

  • Market drivers and restraints

  • Market size

  • Growth prospects

  • Porter’s analysis

  • PESTEL analysis

  • Key market opportunities prioritized

  • Competitive landscape

    • Company overview

    • Financial performance

    • Product benchmarking

    • Latest strategic developments

Downstream processing market quantitative analysis

  • Market size, estimates, and forecast from 2018 to 2030

  • Market estimates and forecast for product segments up to 2030

  • Regional market size and forecast for product segments up to 2030

  • Market estimates and forecast for application segments up to 2030

  • Regional market size and forecast for application segments up to 2030

  • Company financial performance

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