The global healthcare specialty enzymes market size is anticipated to witness rapid growth during forecast period owing to its extensive usage in pharmaceutical industries. Enzymes have gained immense demand in diagnosis and clinical applications in the form of assays and techniques. For instance, enzyme linked immunosorbent assay (ELISA) makes use of peroxidase, alkaline phosphatase, and ß-galactosidase. Rising use of ELISA for diagnosis of noninfectious disease inclusive of hormones, drugs, serum components, and oncofetal proteins/autoimmune diseases.
Whereas, infectious disease diagnosis caused due to bacterial, viral, mycotic or parasitic organisms can be effectively diagnosed via ELISA technique. Enzyme multiplied immunoassay technique (EMIT) makes use of lysozyme and malate dehydrogenase. Analysis of glucose, uric acid, urea, and cholesterol content in blood is also done using the same.
Increase in the incidence of metabolic diseases associated with enzyme abnormality and incorporation of enzymes as disease markers across clinical examinations are contributing factors to the market growth. In addition, specific locations of few enzymes in body tissues makes them a potent method of disease diagnosis. For instance, lactase dehydrogenase (LDH) is present in two different forms in skeletal muscle and heart; thus, changing dynamics of LDH in blood is expected to indicate onset of heart diseases.
Rapid shift from organic synthesis to diagnostic enzymatic applications in pharmaceutical industries has been observed in recent years. This is also supplemented by expansion of access to medical care in developing economies. Factors such as rising demand for preventive medicine, advent of DNA sequencing techniques, and momentum to molecular diagnostics is expected to boost the use of enzymatic diagnostic methods.
Alkaline phosphatases, creatine kinase, alanine aminotransferase, aspartate aminotransferase, sorbitol dehydrogenase (SDH), lactate dehydrogenases (LDH), cholinesterase (ChE), amylase, glutamyl transferase, trypsin, and glutathione peroxidases are incorporated in pathological diagnosis. In addition, these are potent alternatives for radioisotopes that are used in the form of markers in immunoassays. These are further used to identify diverse proteins and hormones.
Companies operating in global market include Novozymes A/S, Codexis Inc., Affymetrix Inc., Advanced Enzymes Technologies Ltd., Amano Enzymes Inc., Biocatalysts Ltd., BBI Solutions, Roche CustomBiotech, Sekisui Diagnostics, Merck, F. Hoffmann-La Roche Ltd., Amano Enzymes, Inc. and Amicogen Inc. Regional companies largely investing in the development of specialty enzymes is expected to drive the growth of emerging markets.
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