GVR Report cover Single-use Bioprocessing Probes And Sensors Market Size, Share & Trends Report

Single-use Bioprocessing Probes And Sensors Market Size, Share & Trends Analysis Report By Sensor Type (pH Sensor, Oxygen Sensor), By Workflow (Upstream, Downstream), By End Use, By Region, And Segment Forecasts, 2021 - 2028

  • Published Date: Jul, 2021
  • Base Year for Estimate: 2020
  • Report ID: GVR-4-68039-250-4
  • Format: Electronic (PDF)
  • Historical Data: 2018 - 2019
  • Number of Pages: 150

Report Overview

The global single-use bioprocessing probes and sensors market size was valued at USD 1.9 billion in 2020 and is expected to expand at a compound annual growth rate (CAGR) of 13.9% from 2021 to 2028. The growing demand for biopharmaceuticals is consequently driving the demand for single-use systems. Thus, the adoption of disposable systems in pre-clinical scale biopharmaceutical production is expected to propel the growth of the market for single-use bioprocessing probes and sensors.

France single-use bioprocessing probes and sensors market size, by sensor type, 2018 - 2028 (USD Million)

The COVID-19 pandemic has created lucrative opportunities for key stakeholders of the market for single-use bioprocessing probes and sensors. The pandemic provides a new perspective on implementation of single-use systems. Major biopharmaceutical companies are experiencing increased demand for bioprocessing technologies, in turn, driving the revenue. For instance, in September 2020, ABEC’s Custom Single Run (CSR) technology was selected by Serum Institute to enhance large-scale, single-use manufacturing of nearly 1 billion doses of Novavax COVid-19 vaccine.

The collaborations between OEMs and independent suppliers of sensors help in delivering complete single-use assemblies with trusted integrity. For instance, in December 2020, Pall Corporation collaborated with Single-Use Support GmbH for advances in the biopharmaceutical sector. The latter company is distributing the RoSS platform, which widens Pall’s portfolio of integrated solutions. Such collaborations are aimed at accelerating the use of disposables sensors across upstream and downstream unit operations.

Furthermore, the development of single-use sensors with expanded use is also expected to boost the growth of the market for single-use bioprocessing probes and sensors. A project such as “Single-use glucose sensors for bioreactor” by Stobbe Tech, C-CIT, and Zurich University of Applied Sciences in the past years which aimed at developing single-use sensors for online measuring of glucose and lactate in bioreactors has positively impacted the revenue growth over the past years.

Technological challenges in the implementation of single-use bioprocessing probes and sensors may hamper market growth. Thus, companies are engaged in focusing their efforts on the development of improved disposable sensors. For instance, Emerson Electric’s Rosemount 550pH single-use sensor and connector offers storage, installation, gamma sterilization, and standardization in a wetted and retracted condition. This creates opportunities for emerging market players to gain considerable market share, thereby driving the market for single-use bioprocessing probes and sensors.

Sensor Type Insights

Being an integral part of a single-use container, pH sensors held the major revenue share of 20.9% in 2020. High product penetration and usage rate have attributed to this large share. Technological advancements in this sensor type, such as the development of a pH sensor with an in-built temperature sensor, are expected to drive the segment. Furthermore, the measurement of Dissolved Oxygen (DO) is one of the most monitored physicochemical parameters in bioprocessing engineering.

The development of disposable sensors that enable users to measure DO separately has driven the segment. The presence of companies like Finesse; Hamilton Company; Polestar Technologies; Eppendorf AG; Scientific Industries, Inc.; and Applikon Biotechnology, Inc., engaged in manufacturing and marketing of disposable sensors to measure DO, have contributed to significant revenue generation of this segment.

Over the past years, several developments have been made in flowmeter technology to address the issues such as incorrect flowmeter installation and material incompatibility, resulting in the lucrative growth of segments. Among all the flowmeters, Coriolis technology delivers the highest level of accuracy and precision and this technology is least affected by the changes in viscosity and conductivity.

Workflow Insights

The upstream segment dominated the market for single-use bioprocessing probes and sensors and accounted for the largest revenue share of 74.2% in 2020. Adoption of single-use bioreactors and media bags by bio manufacturers in the upstream manufacturing process has significantly increased the usage of sensors in this segment. An effective upstream process generally relies on the identification of Critical Process Parameters (CPPs) and utilization of a bioreactor type, which can provide good control over CPPs.

In an upstream process, CPPs that are generally monitored include temperature, Dissolved Oxygen (DO), and pH. In addition, other factors such as culture viability, viable-cell density, nutrient levels, specific growth rate, and other measurable parameters are also considered as CPPs. On the other hand, although single-use technologies have gained significant ground in biomanufacturing, the biggest challenges still lie in separation and purification.

In downstream processing, the affinity capture step and the polishing/purification are recognized as intensive and costly. Overall, less penetration of single-use systems in downstream processes resulted in less revenue share of the market in this segment. However, with constant attempts by operating players to expand the use of disposables in the downstream process, this segment is expected to witness considerable growth in the coming years.

End-use Insights

The biopharmaceutical manufacturers segment dominated the market for single-use bioprocessing probes and sensors and accounted for a major revenue share of 58.9% in 2020. Constant new product developments and accelerated adoption of disposables among contract service providers as well as in-house bio manufacturers to meet the growing global demand for biopharmaceuticals efficiently is one of the major factors for the growth of this segment.

Global single-use bioprocessing probes and sensors market share, by end use, 2020 (%)

Several contract service providers are engaged in expansion of their manufacturing facilities by installing single-use instruments at their plants. For instance, WuXi Biologics, a CDMO and part of WuXi AppTech, is proactively expanding its biomanufacturing capacity with several investments over the course of the past year in single-use technology.

OEMs such as Sartorius Stedim Biotech, GE Healthcare are at the forefront in innovation for single-use assemblies using products from independent suppliers. Suppliers like PendoTECH are involved in selling a substantial volume of its sensors and monitors to OEMs for GMP production, pilot and toxicology studies, and clinical batches. New product launches by independent suppliers directly benefit the OEMS, thus boosting revenue of this segment.

Regional Insights

North America dominated the single-use bioprocessing probes and sensors market and accounted for the major revenue share of over 34.0% in 2020. The U.S. market is home to most of the biopharmaceutical manufacturers such as CMC Biologics; FUJIFILM Diosynth Biotechnologies U.S.A., Inc.; Amgen; DPx Holdings; and AbbVie, Inc. In addition, the ancillary steps associated with bioprocessing, such as viral vector manufacturing, are undertaken by a substantial number of players that are headquartered in the region.

Moreover, the highest revenue-generating OEMs like GE Healthcare, Thermo Fisher, and Pall Corporation are headquartered in the U.S., thereby contributing to the largest revenue share of the market in North America. In addition, the largest revenue share of the U.S. market is also supported by the presence of several small players like PBS Biotech, Inc.; Entegris, Inc.; and others.

In Asia Pacific, the market for single-use bioprocessing probes and sensors is expected to register the fastest CAGR throughout the forecast period owing to the recognition of Asian countries as a hub for biopharmaceutical outsourcing. Growing markets such as China, India significantly increase the revenue generation in the region. Moreover, the incorporation of disposable products by Asia-based bio manufacturers from key global suppliers in their cGMP biomanufacturing facility is driving regional growth.

Key Companies & Market Share Insights

The key players are undertaking various strategic initiatives such as alliances with OEM and new product development with improved technical intricacies to boost their organic revenue growth as well as market presence. OEMs are engaged in obtaining licenses for the incorporation of sensors in their single-use assembly. Moreover, companies like Pfizer, Amgen, and Abbvie that account for major revenue share in biopharmaceuticals have begun making investments in single-use facilities. These companies are engaged in establishing partnerships with major OEMs to establish their single-use plants.

Furthermore, the single-use probes and sensors manufacturers are engaged in the expansion of manufacturing capabilities and development of new products to meet the growing demand in the biopharmaceutical industry. For instance, in July 2020, Hamilton Company introduced a revised version of VisiTrace DO—an optical dissolved oxygen sensor. The new version is integrated with the HART interface. Some of the prominent players in the single-use bioprocessing probes and sensors market include:

  • Thermo Fisher Scientific

  • Sartorius AG

  • Danaher Corporation

  • PreSens Precision Sensing GmbH

  • ABEC

  • Hamilton Company

  • PendoTECH LLC

  • Equflow

  • Parker Hannifin Corporation

  • Malema Engineering Corporation

  • Dover Corporation

  • Broadley-James Corporation

  • High Purity New England, Inc.

  • Cole-Parmer Instrument Company, LLC.

  • ESI Ultrapure

Single-use Bioprocessing Probes And Sensors Market Report Scope

Report Attribute

Details

Market size value in 2021

USD 2.3 billion

Revenue forecast in 2028

USD 5.4 billion

Growth Rate

CAGR of 13.9% from 2021 to 2028

Base year for estimation

2020

Historical data

2018 - 2019

Forecast period

2021 - 2028

Quantitative units

Revenue in USD Million and CAGR from 2021 to 2028

Report coverage

Revenue forecast, company share, competitive landscape, growth factors, and trends

Segment coverage

Sensor type, workflow, end use, region

Regional scope

North America; Europe; Asia Pacific; Latin America; Middle East & Africa

Country scope

U.S.; Canada; Germany; U.K.; Italy; Spain; France; China; India; Japan; South Korea; Australia; Brazil; Mexico; South Africa; Saudi Arabia

Companies profiled

Thermo Fisher Scientific; Sartorius AG; Danaher Corporation; PreSens Precision Sensing GmbH; ABEC; Hamilton Company; PendoTECH LLC; Equflow; Parker Hannifin Corporation; Malema Engineering Corporation; Dover Corporation; Broadley-James Corporation; High Purity New England, Inc.; Cole-Parmer Instrument Company, LLC.; ESI Ultrapure

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Segments Covered in the Report

This report forecasts revenue growth at global, regional, and country levels and provides an analysis of the latest industry trends in each of the sub-segments from 2018 to 2028. For the purpose of this study, Grand View Research has segmented the global single-use bioprocessing probes and sensors market report on the basis of sensor type, workflow, end use, and region:

  • Sensor Type Outlook (Revenue, USD Million, 2018 - 2028)

    • pH Sensor

    • Oxygen Sensor

    • Pressure Sensors

    • Temperature Sensors

    • Conductivity Sensors

    • Flow Meters & Sensors

    • Others

  • Workflow Outlook (Revenue, USD Million, 2018 - 2028)

    • Upstream

    • Downstream

  • End-use Outlook (Revenue, USD Million, 2018 - 2028)

    • Biopharmaceutical Manufacturer

      • CMOs & CROs

      • In-house Manufacturer

    • Labs & Academic/ Clinical Research Institutes

  • Regional Outlook (Revenue, USD Million, 2018 - 2028)

    • North America

      • U.S.

      • Canada

    • Europe

      • Germany

      • U.K.

      • France

      • Italy

      • Spain

    • Asia Pacific

      • Japan

      • China

      • India

      • Australia

      • South Korea

    • Latin America

      • Brazil

      • Mexico

    • Middle East Africa (MEA)

      • South Africa

      • Saudi Arabia

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