Specialty Enzymes Market Size, Share & Trends Analysis Report By Source (Plants, Animal, Microorganisms), By Product (Carbohydrase, Proteases, Polymerases & Nucleases), By Application, By Region, And Segment Forecasts, 2023 - 2030

Report Overview

The global specialty enzymes market size was valued at USD 5.31 billion in 2022 and is expected to grow at a compounded annual growth rate (CAGR) of 6.6 % from 2023 to 2030. The growth of the product market is attributed to the growing prevalence of chronic diseases such as cancer and rheumatoid arthritis. Furthermore, the expansion of food industries drives the demand for specialty enzymes. The enzymes such as lipases, amylases, proteases, rennet, pectinases, invertases, cellulases, and glucose oxidase play a vital role in the food processing industry. However, the complexities in biosimilar development may hinder the market's growth.

Utilizing specialty enzymes offers swift and practical solutions to these issues, contributing to market expansion. Specialty enzymes are widely employed in various diagnostic methods, including DNA modification and sequencing. The projected decline in DNA modification and sequencing costs is expected to drive the demand for enzymes in research, biotechnology, and medicinal applications. Moreover, the aging population in affluent countries is anticipated to increase the requirement for specialized enzymes in the healthcare sector.

Furthermore, the development of innovative diagnostic methods, reduced consumption of healthcare enzymes, and technological innovation are among the key drivers propelling the global specialty enzyme market. However, one of the challenges faced by the market is the need for more consumer awareness regarding the benefits of specialized enzymes.

Legal & ethical issues and a need for more awareness among consumers regarding the advantages of specialty enzymes, especially in emerging countries, are also supposed to threaten the market growth. Nevertheless, the increasing industrialization rate and advanced technologies chosen in the pharmaceutical industry in emerging markets are expected to hold future opportunities for market participants.

Source Insight

The microorganism segment dominated the market with a revenue share of 74.9% in 2022. This growth is attributed to the increasing use of amylases in biotechnology, and pharmaceutical industries would drive the microorganism-derived specialty enzymes market growth. Microbial enzymes are used in various industries, including chemical, fermentation, agricultural, pharmaceutical, and food production.

Microbial enzymes are vital for medical treatments as they are inexpensive, consistent, and simple to isolate. The main advantage of microbial enzyme production is that it quickly yields high yields on low-cost media. These factors are expected to boost the segment's growth potential over the forecast period. Some commercial enzymes such as amylase, invertase, papain, bromelain (bromelin) ficin, and malt diastase are derived from plant sources. These enzymes have played an essential part in food production, including syrups, bakery products, alcoholic beverages, dairy products, etc.

Animal-derived enzymes are naturally occurring proteins that are ubiquitous in living organisms. They are derived from animals used as food sources and safely consumed as part of the human diet throughout human history. The animal segment is the fastest growing during the forecast period owing to the rise in the prevalence of digestive disorders and the rise in demand for animal-derived enzymes as health supplements drive the market growth.

Product Insight

Carbohydrases segment dominated the market with a revenue share of 37.4% in 2022. This growth is attributed to the increasing consumption of dietary supplements and digestive enzymes. Specialty enzymes are widely used in research & biotechnology applications due to the growing R&D activities to increase enzyme yield through altered specificity, increased stability, and fermentation.

Polymerase and nuclease products are also anticipated to witness lucrative growth due to the significant use of these enzymes in molecular biology applications, such as recombinant DNA and polymerase chain reactions. Gene therapy holds promise for treating many diseases, such as cancer, cystic fibrosis, heart disease, diabetes, hemophilia, and AIDS. Thus, an upsurge in cancer prevalence propels this segment's growth.

Lipases, phospholipases, and cellulases are prominent enzymes in the biofuel sector. For instance, enzymes such as phospholipase and lipase play a vital role in biodiesel production. Numerous biodiesel manufacturers have commercialized their biodiesel production by adding enzymatic processes. From a processing standpoint, lipase converts free fatty acids (FFAs) to fatty acid methyl esters (FAME), while phospholipase converts diacylglycerol, which acts as a substrate for lipase. Such factors are responsible for increasing yield and reducing chemical waste.

Application Insight

The pharmaceutical segment dominated the market with a more than 40.6% revenue share. This growth is attributed to the growing population, high consumer demand, and rising disease awareness. Cysteine proteinases, streptokinase, asparaginase, deoxyribonuclease, glucocerebrosidase, urokinase, pegademase, and hyaluronidase are the prominently used enzymes in the pharmaceutical sector. The critical applications of specialty enzymes in the pharmaceutical industry include diagnosing diseases, promoting wound healing, and killing disease-causing microorganisms. Further, increasing research & development has made it possible for specialty enzymes to be used in drug formulation and delivery.

Enzymes find applications in research & biotechnology as they are used further in several end-use industries and possess health benefits. Enzymes such as protease, dismutase, elastase, anhydrase, tyrosinase, and catalase are generally used in cell biology to help the cell carry out quick chemical reactions. The research & biotechnology sector is responsible for developing new medicines and diagnostic solutions. Ascending demand for medicinal drugs, extensive research activities, and substantial funding initiatives are expected to drive this sector, which, in turn, is likely to fuel the demand for enzymes in the coming years.

Enzymes act as biological catalysts and fasten metabolic reactions. They are used in different industries and laboratories for degrading wastes and oil spills into harmless compounds, in the fermentation process of alcoholic beverages, and in cleaning fat stains. Enzymes used as biocatalysts help reduce waste products, promote high energy savings, lower the use of solvents required, improve productivity, and contribute to cost savings.

The R&D centers of several companies focus on the evaluation, validation, development, and upscaling of technologies and innovative enzyme formulation for commercial processing and human welfare. Furthermore, they are used to diagnose bone diseases, autoimmune & inflammatory diseases, cancer, diabetes, liver diseases, myocardial infarction, kidney disorder, pancreatitis, and skin disorders. Moreover, rising government spending in developed countries for medical and diagnostic purposes is anticipated to create growth opportunities for the market over the forecast period.

Regional Insight

North America dominated the market with a revenue share of 41.7% in 2022. This is attributed to the growing number of specialty enzyme product approvals and product launches for treating diseases. Technological advancements in the region have made enzymes available for various applications, leading to positive market growth in the coming years.

Europe is one of the major producers of medicinal, pharmaceutical, and cosmetic products. The presence of major pharmaceutical and cosmetics companies such as AstraZeneca plc, Bayer AG, Beiersdorf, and GlaxoSmithKline plc. Hoffmann-La Roche Ltd, Henkel AG & Co, Merck KGaA, Novartis AG, Sanofi, Novo Nordisk A/S, New Avon Company, L’Oréal, and Unilever in the region is expected to propel the demand for specialty enzymes. Moreover, the rapidly expanding pharmaceutical sector, due to the presence of significant biotech companies, is likely to drive the demand for specialty enzymes in pharmaceutical, biocatalyst, and research & biotechnology applications over the forecast period.

Asia Pacific is estimated to grow fastest during the forecast period owing to increased incidence of cardiovascular diseases, high prevalence of various cancers, and a rise in product launches in the region. The increase in foreign investments in the country's pharmaceutical sector is estimated to provide further scope for the consumption of specialty enzymes over the forecast period. Furthermore, the growing consumption of processed food products increases spending on high-quality products, and customer inclination for natural raw materials used in the products is driving the market.

Key Companies & Market Share Insights

The market is moderately fragmented with the presence of small and large players in the market. Key market participants include Advanced Enzyme Technology Ltd., Amano Enzyme Inc., Bbi Enzymes Ltd., BASF SE, Codexis Inc., Nagase & Co. Ltd., Life Technologies, Roche Holding Ag., Sanofi S.A. Market players invest in innovation, product launches, mergers, and acquisitions to improve their market share and gain a competitive edge. For instance, in September 2021, Sanofi S.A. appointed Orsini Specialty Pharmacy as a distribution partner for Nexviazyme, used for treating patients one year of age and older with late-onset Pompe disease. With this move, Sanofi S.A. plans to expand its global presence due to the growing number of enzyme replacement therapies. Some of the prominent players in the global specialty enzymes market are:

• Advanced Enzyme Technology Ltd.

• Affymetrix Inc.

• Advanced Enzyme Technology Ltd.

• Amano Enzyme Inc.

• Bbi Enzymes Ltd.

• BASF SE

• Codexis Inc.

• Nagase & Co. Ltd.

• Life Technologies

• Roche Holding Ag.

• Sanofi S.A.

Specialty Enzymes Market Report Scope

Global Specialty Enzymes Market Report Segmentation

This report forecasts revenue growth at country levels and provides an analysis on the latest industry trends in each of the sub-segments from 2018 to 2030. For the purpose of this study, Grand View Research has segmented the global specialty enzymes market report on the basis of source, product, application, and region:

• Source Outlook (Revenue, USD Million, 2018 - 2030)

  • Plants

  • Animals

  • Microorganisms

• Product Outlook (Revenue, USD Million, 2018 - 2030)

  • Carbohydrase

  • Proteases

  • Lipases

  • Polymerases & Nucleases

  • Other Products

• Application Outlook (Revenue, USD Million, 2018 - 2030)

  • Pharmaceutical

  • Research & Biotechnology

  • Diagnostics

  • Biocatalyst

• Regional Outlook (Revenue, USD Million, 2018 - 2030)

  • North America

    • U.S.

    • Canada

    • Mexico

  • Europe

    • Germany

    • UK

    • France

    • Spain

    • Italy

  • Asia Pacific

    • China

    • Japan

    • India

    • South Korea

    • Indonesia

    • Australia

  • Central & South America

    • Brazil

    • Argentina

  • Middle East & Africa

    • Saudi Arabia

    • Turkey