Gastroesophageal Reflux Disease (GERD), also known as acid reflux or heartburn, is a long term gastrointestinal disorder that affects huge number of adults across the globe. The risk factors responsible for causing heartburn include aging, obesity, certain medicines, and unhealthy lifestyle habits such as smoking and alcohol consumption.
Janssen Products, LP received the U.S. FDA approval in 1995 for Doxil, a liposomal doxorubicin formulation to treat Kaposi’s sarcoma, multiple myeloma, breast, and ovarian cancer. The distribution and marketing of Doxil was done by a subsidiary of Johnson and Johnson (J&J), Janssen Products, LP, and was manufactured by Ben Venue Laboratories. However, there was limited availability of Doxil due to the production problems with third-party manufacturer in 2011.
Osteoporosis drugs are incorporated in the treatment of bone disease, resulting in bone density loss and abnormal tissue structure. In majority of females, menopause increases in the likelihood of acquiring osteoporosis thus heightening the demand for the overall market. Biophosphonates, hormones therapy and rank ligand inhibitors are commonly prescribed medications for the efficient treatment of osteoporosis.
“Biologics” refer to a wide range of medicinal products such as blood or blood components, tissue, somatic cells, vaccines, recombinant therapeutic proteins, gene therapy manufactured from/comprising of living cells that are used as therapeutics to treat diseases. While chemical drugs are produced through chemical synthesis and mostly taken orally (as small molecules are easily absorbed in the body), biologics are made through complex biological processes and are mostly injected because proteins, which are large molecule substances, degrade in the stomach if administered orally.
Marijuana belongs to a family of plants named cannabaceae. It is mainly categorized on the basis of its shape, height, smell, and color. In the ancient Chinese tradition, marijuana was used for the management of malaria, reproductive system disorders, constipation, rheumatic pain, etc. Over 70 psychoactive compounds with the chemical structure of tetrahydrocannabinol (THC) have been identified.
Depression is the leading cause of disabilities worldwide as it impacts normal day-to-day activities of an individual. These disorders need to be treated at an early stage to avert the development of suicidal conditions in mentally depressed individuals.With surging incidence of depressive disorders, the market witnesses growth due to increasing prescription rates.
Globally, recent introductions & expected launch of the urate-lowering agents in the market, rising incidence of gout due to changing lifestyle, and increasing adoption of the newer agents, during the forecast period are likely to drive the market over the coming years. Presently, gout affects about 1% of the world’s population and 5% of arthritis sufferers across the globe. Several studies estimated that in 2012, prevalence of gout in the U.K. was 2.49% of total population, which had increased by approximately 63.9% as compared to 1997.
Prior to clinical studies for any new molecule, well-established preclinical studies must be performed to allow the FDA to provide the Investigational New Drug (IND) approval. This growing attention toward preclinical analysis is expected to support growth of rat model market.
In current scenario, contract manufacturing services for small as well as large-molecule drug product is popular and is an ever increasing trend within pharmaceutical sector. Insufficient internal resources to cope with increasing therapeutic demand is driving this vertical.
Alternative medicine includes a number of traditional medicinal and faith healing treatments where a disease is treated with organic products, natural methods, and faith healing. These are generally used in the treatment of chronic ailments and pains. Most prominent forms of these therapies in usage include application of ayurvedic medicine and naturopathic treatment, acupuncture, mind/body healing, yoga and magnetic intervention.
The global population has become an easy target for a number of diseases, many of them being life-threatening. Cancer has been a major cause of mortality in the past many years, with 14 million new cases being observed in 2012 and 8.2 million cancer-related deaths. This number rose steadily to 17 million new cases in 2018, with 9.6 million deaths. Not only cancer, CVD, diabetes, and Alzheimer’s and Parkinson’s diseases have become very pronounced among the general population.
Drugs are the first line therapy for almost every small or major illness. With the concept of drugs comes the term drug delivery systems, which can be said of as a device or a formulation that is be used to introduce a therapeutic substance within the body. The said device or formulation helps in optimizing effectiveness of the drug within the body. A common example can be taken of as nasal spray, which is most commonly used by people suffering from nasal congestion.
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