Plant based excipients are substances or compounds that affect the quality of the finished product in addition to the active pharmaceutical ingredients and packaging components. However, they make up almost the entire formulation and are crucial for effective planning of pharmaceutical products enabling transportation of drug substance without itself having any therapeutic effect.
Plant-based materials have attracted a great deal of interest recently because of their extensive use in pharmaceuticals, including as bases in suppositories, bases for gels, diluents and binders in tablets, thickeners in oral liquids, colloids for protection in suspensions, and gelling agents for gels. They are also used in cosmetics, paints, textiles, and papermaking. Starch,alginates, agar, carrageenin, guar gum, gelatin, acacia gum,tragacanth, xanthan gum, pectin, and numerous flavoring,sweetening, and coloring agents are just a few examples of the many plant-based pharmaceutical excipients that are frequently used in the pharmaceutical industry as binding agents, stabilizers, sustaining agents, gelling agents, thickening agents, and coating materials.
Before being added to dosage forms that have been approved for indefinite quantities, excipients need to adhere to tight regulatory requirements. Natural excipients, such as flavorings, have several advantages over artificial ones, including being non-toxic, more affordable, and widely accessible. The pharmaceutical industries are leaning toward using these flavored excipients in formulation development because of the rising awareness surrounding them.The thaumatin, carrageenin, agar, storax, gum tree, and gum plant-derived gums and mucilage from natural sources meet a variety of needs for pharmaceutical excipients. Comparing them to their manufactured counterparts, they are more stable and pose less regulatory issues. An excipient must be stable and safe because they are a crucial component of health goods. Numerous stability testing techniques are carried out to prevent the use of incompatible excipients.
North America dominated the overall market in 2022 which can be attributed to the growing geriatric population and rising awareness among the population regarding health. Moreover, the advantages offered by natural excipients such as non-toxicity, high affordability, and easy availability is further driving the growth of the market in the region. Moreover, key players in the region are focusing on developing newer products to meet the rising demand for pharmaceuticals. For instance, in December 2022, Evonik announced the launch of PhytoSquene, which provides the market a plant based excipient alternative to animal based excipient.
Attribute |
Details |
Chemical Nature |
Carbohydrates, Proteins, Polymers, Minerals, Glycoside & Waxes, Esters, Ethers & Carboxylic Acids |
Application and Functions |
Binders & Diluents, Glidants, Lubricants & Disintegrants, Film forming & Coating Agents, Plasticizers, Suspending Agents, Preservatives & Antioxidants, Colorants & Flavoring Agents |
Major companies operating in the market include Roquette Frères, EVONIK, DFE Pharma, Lonza, and BASF Corporation. These players are focusing on geographical expansion and product launches to maintain their presence in the market. For instance, in September 2022, Roquette acquired Crest Cellulose, an India-based excipient manufacturer to meet the demand for high-quality plant-based excipient.
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