Excipients are common ingredients used in pharmaceutical formulations. They are added to active pharmaceutical ingredients either to bulk up the formulation, mask the taste, or enhance bioavailability of the formulation. They can be added to all forms of drugs, solid oral or liquid oral, and to formulations through various routes of administration. They can also influence drug delivery mechanisms.
In the current scenario, technological advancement in large-scale downstream bioprocessing systems is an ever-increasing trend in biotechnology. Popularity of single-use bioprocessing instruments, advancements in existing separation & purification techniques are expected to drive growth in the near future.
Advanced gastrointestinal drug eluting stents (DES) were introduced in the market to overcome certain disadvantages such as restenosis and neo-intimal hyperplasia associated with the first generation stents namely, bare metal and plastic stents. In addition, a paradigm shift from conventional invasive procedures to minimally invasive procedures is fueling the demand for GI stents. Thus, DES is widely used since it supports minimally invasive procedures.
Superdisintegrants are added to drug formulation in order to facilitate the dissolution of tablet or capsule content into reduced particles. It is usually used in lesser quantities in the solid dosage form, typically ranging from 1-10% by weight, which is relative to the total weight of the dosage unit. Some of the widely used products include crospovidone, croscarmellose sodium and sodium starch glycolate.
Defibrillation is a treatment for ventricular fibrillation and nonperfusion ventricular tachycardia. These episodes can cause Sudden Cardiac Arrest (SCA). Almost 50.0% of the cardiovascular deaths can be attributed to SCA.Due to imbalance in the electrical system of the heart, the heart rhythm is affected, which leads to arrhythmias. This condition may lead to SCA.
“Regenerative medicine” is an emerging scientific and medical field that offers therapies to treat diseases by regaining and/or restoring structure and function of damaged organs, tissues and cells. These medicines regenerate body’s ability to restore the functions and structure as a part or whole treatment protocol. Strong pipeline of products for the treatment of cardiovascular, neurodegenerative, oncology, and rare genetic disorders exists. Ability to cure the incurable diseases reflects high market potential over the coming years.
2016 witnessed a continued increase in contract manufacturing operations with an objective to cut back on in-house costs and capacity while maintaining the product quality and timelines. With growing pressure of biopharmaceutical demand and R&D costs, CMOs/CROs have significantly grown to gain ground in biopharmaceutical industry.
Plasma-rich platelet (PRP) treatment is being highly touted as one of the most successful procedures for management of orthopedic diseases and sports injuries. Adoption of this therapy is now gaining momentum as it is becoming the preferred choice of treatment for reducing wrinkles, scars, or even dark circles, owing to the treatment’s benefits.
Biomarkers are substances or enzymes present in the body that indicate presence or occurrence of a certain disease. Cancer biomarkers can be a molecule expressed by the body as a response to tumor presence. The biomarkers are majorly genetic, proteomic, epigenetic or phenotypic in nature. Most of the cancer biomarkers can be assayed in noninvasive fluids such as blood & serum and are easily detectable without causing much pain.
Cartilage is a flexible and semi-rigid avascular connective tissue that performs supporting function and prevents friction between the bones due to its shock absorbing nature. There are three types of cartilage such as elastic (yellow), hyaline, and fibrocartilage. Damage to the cartilage obstructs the normal movement of knee, hip, shoulder, finger, elbow, foot and ankle, and can cause pain. If left untreated, the joints may get damaged.
Medical electrodes function by transferring the ionic current energy of the body into electrical current that can be amplified and examined for diagnosis of various cardiac, ocular, nervous, and muscular diseases. Medical electrodes play a vital role in providing ideal electrical contact between the patient and apparatus/device used to record or measure activity. Medical electrodes contain lead, metal, and electrode-conducting paste or gel.
Histology and cytology are studies of chemical composition, microscopic structure, &functioning of tissues and cells respectively through advanced medical devices. Different types of microscopes can be used to study the structure of cells and tissues to determine the cause or nature of a disease. Recent developments in diagnostic testing and healthcare system are expected to improve the pathology landscape across the globe.
Tourniquets are mechanical devices that are used during surgeries for temporary control of blood circulation. Multiple research studies have revealed that commercially available tourniquet systems can be effective in the management of uncontrolled, life-threatening extremity hemorrhage
The microscopes market has been witnessing considerable demand due to rise in funding in emerging applications such as nanotechnology. A major driver for this market includes research and development in the field of nanotechnology in order to commercialize it, since nanotechnology has a variety of niche applications. Additionally, microscopes are used in semiconductors, life sciences and material sciences. Drivers for the market include research and development for advanced microscopes used in life sciences and the growing semiconductor market in the Asian and Latin American regions.
The increasing women population of age 35 to 65 years across the globe engenders a greater demand for anti-aging cosmetic and aesthetic treatments. Owing to the distinctive viscoelastic and moisturizing properties coupled with lower toxicity levels offered by hyaluronic acid-based products, the demand for this polymer in dermal fillers is expected to grow. In addition, its application in the treatment of vesicoureteral reflux is anticipated to grow due to the minimally invasive nature of the involved procedures.
The sports medicine market is inclusive of numerous medical equipment that are routinely utilized to address mild to severe injuries caused due to sports and other physical activity. Chronic diseases and lifestyle-related habits contribute to approximately 75.0% of the health costs.
The brain cells are active all the time and they communicate through electrical impulses. EEG is an electrophysiological and noninvasive monitoring technique that is used to record electrical activity of the brain. EEG records the spontaneous electrical activity of the brain by using multiple, small, flat metal discs (electrodes) that are placed on the scalp.
Orthopedic & related disorders are usually seen amongst the young and geriatric population. Orthopedic diseases related to musculoskeletal system are increasingly contributing to the growth of orthopedic braces and supports market. Incidence of musculoskeletal disorders, such as osteoarthritis and osteoporosis, is rising.
Diabetes mellitus is a chronic disease affecting people of nearly all age groups. Type 1 diabetes, indicating insulin deficiency, is generally found amongst pediatric population and young adults. As per the estimates of the American Diabetes Association, only 5% of the overall diabetic population have type 1 diabetes. On the other hand, type 2 diabetes indicates insulin resistance and is the most common type of diabetes occurring amongst people.
Bone densitometer is a medical device designed to accurately measure bone density. It is primarily use in the detection of metabolic bone diseases, such as osteoporosis, which are characterized by low bone mineral density and high risk of fractures. Osteoporosis is also characterized by gradual loss in calcium and bone structural changes.
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